To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Spécifications
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.01 mg
- Biological activity:Biological activity was determined by its ability to neutralize BMP - 6 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is < 2.0 μg/mL of TSG.
- Protein synonyms:TSG|PSEC0250|Twisted gastrulation protein homolog 1
- Protein/peptide name:TSG
- Purity:>98%
- Formulation:Lyophilized
- Cat. no.:10072-756
- Supplier No.:40-205
Spécifications
A propos de cet article
Twisted Gastrulation Protein (TSG) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex. Recombinant human TSG is a 199 amino acid 22.2 kDa protein containing the BMP/TGFβ binding portion of the full length TSG protein.
Store in working aliquots at -20°C. Avoid freeze/thaw cycles.