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Spécifications
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.01 mg
- Biological activity:The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC - 5 chondrogenic cells in the range of 2.0 - .0 μg/mL.
- Protein synonyms:SGM1|CDMP2|KFS1|MCOP4|SCDO4|MCOPCB6|LCA17|BMP13|GDF16GDF-6|KFSL|KFM|KFS
- Protein/peptide name:Cdmp-2
- Purity:>95%
- Formulation:Lyophilized
- Cat. no.:10072-752
- Supplier No.:40-202
Spécifications
A propos de cet article
BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant human BMP-13/CDMP-2 is a 27.0kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.
Store in working aliquots at -20°C. Avoid freeze/thaw cycles.