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Spécifications
- Antibody type:Primary
- Antigen name:angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- Clonality:Polyclonal
- Gene ID:Q9BYF1
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:ACE2
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:ACE2
- Storage buffer:ACE2 Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 89 kDa Observed: 95 kDa
- Storage temperature:ACE2 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:ACE2 antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of human ACE2. The immunogen is located within the last 50 amino acids of ACE2.
- Tested applications:E, WB, IHC, IF
- Purification:ACE2 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:89415-632
- Supplier No.:3217
Spécifications
A propos de cet article
ACE2 Antibody: Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
Type: Primary
Antigen: ACE2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human