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Ac-Trp-Glu-His-Asp-AMC
Ac-Trp-Glu-His-Asp-AMC
# de catalogue I-1715.0005BA
Fournisseur:  Bachem Americas
Numéro CAS:  
Ac-Trp-Glu-His-Asp-AMC
# de catalogue I-1715.0005BA
Fournisseur:  Bachem Americas
Numéro CAS:  

Spécifications

  • CAS No.:
    189275-74-9
  • Size:
    5 mg
  • Storage conditions:
    –20 ± 5 °C
  • MDL No.:
    MFCD01318829
  • Protein/peptide name:
    Ac-Trp-Glu-His-Asp-AMC
  • Molecular weight:
    784.78
  • Sequence:
    Ac-Trp-Glu-His-Asp-AMC
  • Molecular formula:
    C₃₈H₄₀N₈O₁₁
  • Cat. no.:
    I-1715.0005BA
  • Supplier No.:
    I-1715.0005

Spécifications

A propos de cet article

With a kcat/Km of 3.3 · 10⁶ M⁻¹s⁻¹ the fluorogenic caspase-1 substrate Ac-WEHD-AMC is cleaved 50-fold more efficiently than I-1630. This result indicates that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.

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