beta-Amyloid (10-20)
Catalog # H-1388.0001BA
Supplier: Bachem Americas
CAS Number:
Specifications
- CAS No.:152286-31-2
- Size:1 mg
- Protein/peptide name:beta-Amyloid (10-20)
- MDL No.:MFCD00467025
- Sequence:H-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-OH
- Molecular weight:1446.67
- Molecular formula:C₇₁H₉₉N₁₇O₁₆
- Storage conditions:–20 ± 5 °C
- Cat. no.:H-1388.0001BA
- Supplier No.:H-1388.0001
Specifications
About this item
The amyloid precursor protein (APP) is cleaved within the amyloid β-protein region by a putative APP secretase to release its extracellular portion. Gelatinase A, the matrix metalloproteinase MMP-2, possesses such APP secretase-like activity, effectively hydrolyzing also the synthetic amyloid β-protein fragment (10-20) YEVHHQKLVFF at the normal processing site, the Lys¹⁶-Leu¹⁷ bond (Km approx. 0.13 mM).
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