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Spécifications
- Antibody type:Primary
- Antigen name:Interleukin 6
- Clonality:Polyclonal
- Gene ID:3569
- Host:Chicken
- Isotype:IgY
- Reactivity:Human
- Antigen symbol:IL6
- Conjugation:Unconjugated
- ELISA:Yes
- Size:50 μg
- Western blot:Yes
- Antigen synonyms:HSF|HGF|IFNB2|interferon beta 2|BSF2|IL-6
- Storage buffer:PBS, pH 7.2, containing 0.02% sodium azide
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Immunogen:The immunogen corresponding to a region within amino acids 30 and 212 of human IL-6.
- Tested applications:ELISA, WB
- Purification:Affinity purified with antigen
- Cat. no.:89367-246
- Supplier No.:GTX14038
Spécifications
A propos de cet article
Interleukin 6 (IL6) is a multifunctional 24 kD protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass. IL6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL6 appears to interact with IL2 in the proliferation of T lymphocytes. IL6 potentiates the proliferative effect of IL3 on multipotential hematopoietic progenitors.
ELISA: Use at an assay dependent dilution. WB: Use at a dilution of 1/1000. Predicted molecular weight: 26 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: IL6
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Chicken
Isotype: IgY
Reactivity: Human