TransIT®-Lenti for High Titer Lentivirus Production
Lentivirus has become a central gene delivery tool capable of infecting both dividing and non-dividing cells for robust and stable transgene expression.
HEK 293T cells are commonly used for lentivirus production due to high transfection efficiencies and protein expression levels; however, the lentivirus platform is often limited by insufficient viral titers requiring concentration before use.
To address this limitation, Mirus Bio developed the TransIT® -Lenti Transfection Reagent for enhanced delivery of the essential vectors required for higher-titer lentivirus production.
TransIT®-Lenti Transfection Reagent is designed to enhance delivery of packaging and transfer vectors to adherent HEK 293T cell types and increase recombinant lentivirus production. Features and benefits of TransIT®-Lenti include the following:
- High Performance – Provide up to eight-fold higher functional titers
- Simple Protocol – No media change required, single harvest
- Animal Origin Free – Regulatory friendly