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 Guide to Selecting Tubing for Pumps and Fluid Handling Systems | Avantor

Guide to Selecting Tubing for Pumps and Fluid Handling Systems

The right pump tubing is crucial when building your fluid processing pump system. Before you choose, consider all aspects of your application: chemical compatibility, operating temperature, pressure, necessary regulatory approvals, gas permeability of the tubing, and cleaning/sterilization requirements.

Use the "Tubing Selection Guide" below to help you select the appropriate tubing for your application. The Chemical Compatibility guide and the chemical resistance summary in the table below are only guidelines. Chemical resistance and tubing wear may vary according to use always test the tubing you select under the actual conditions.

We are here to help you determine just the right tubing for your pump and fluid handling needs. Learn more about chemical classifications and formulations below.

Chemical Resistance Classifications

A — No damage after 30 days of constant exposure.
B — Little or no damage after 30 days of constant exposure.
C — Some effect after 7 days of constant exposure. Effects may include: cracking, crazing, loss of strength, discoloration, softening, or swelling. Softening and swelling are reversible in some cases.
D — Not recommended for continuous use. Immediate damage may occur.
"_" — Test data unavailable or not applicable.

FormulationOperating
temperature
Resin
certification(s)
DurometerChemical resistance summaryPermeability (approx)†
Units: {cc-mmsec-cm2-cm Hg } x 10-10
Acids,
weak
Acids,
strong
Bases,
weak
Bases,
strong
OzoneUV
light
CO2H2O2N2
Bev-A-Line® IV-60 to 160°F
(-51 to 71°C)
FDA, USP, USDA,80 (D)BDBBD     
Bev-A-Line® V-60 to 200°F
(-51 to 93°C)*
National Formulary80 (D)BBBBD     
Bev-A-Line® XX-60 to 160°F
(-51 to 71°C)
FDA*, NSF*55 (D)CDCDCA    
C-FLEX®-100 to 275°F
(-73 to 135°C)
FDA, USP, USDA, GMP50 (A)AAAA B  150 
Chemfluor® 367-400 to 450°F
(-240 to 260°C)
FDA58 (A)AAAAA     
Copper-60 to 400°F
(-53 to 204°C)
None DDCCAA    
EPDM food-grade;
PTFE-lined;
wire-reinforced
-40 to 300°F
(-40 to 148°C)
FDA, USDA, 3A ABAA      
ETFE-150 to 302°F
(-101 to 150°C)
GMP75 (D)AAAAAA    
FEP-454 to 400°F
(-270 to 205°C)
FDA, USP, GMP55 (D)AAAAAA5.91.3142.0
Gum rubber-15 to 158°F
(-26 to 70°C)
GMP35 (A)ADABCD1311492307118
Hypalon®40 to 220°F
(4 to 104°C)
None70 (D) A        
Kynar®-40 to 260°F
(-40 to 127°C)
FDA, USP, USDA80 (D)AAAAAA    
MFA-103 to 482°F
(-75 to 250°C)
USP59 (D)AAAAAA    
Norprene®-75 to 275°F
(-60 to 135°C)
GMP61 (A)ABACAB1200 80200
Norprene® food-grade-60 to 275°F
(-51 to 135°C)
FDA, NSF, GMP61 (A)ABACAB1200 80200
Norprene® pressure-60 to 275°F
(-51 to 135°C)
FDA, 3A, NSF61 (A)ABACAB1200 80200
Nylon-60 to 200°F
(-51 to 93°C)
None ADACCD20195.41.1
PEEKUp to 212°F
(Up to 100°C)
None AAAAAA    
PFA-320 to 500°F
(-195 to 260°C)
FDA, USP, GMP60 (D)AAAAAA    
PFA-450 high-purity-320 to 500°F
(-195 to 260°C)
FDA, GMP60 (D)AAAAAA    
PharMed®-75 to 275°F
(-59 to 135°C)
FDA, USP, NSF, GMP64 (A)ABACAB1200 80200
Polyethylene-100 to 175°F
(-73 to 80°C)
FDA, USDA50 (D)ADBBBA280 6020
Polyethylene,
FEP-lined
-100 to 175°F
(-73 to 80°C)
FDA, GMP AAAAAA5.9*1.3*14*2.0*
Polyimide-418 to 896°F
(-250 to 480°C)
USP, NEMA AAAAAA    
Polypropylene32 to 250°F
(0 to 121°C)
FDA, USDA75 (D)ADBBCD90 254
Polyurethane
(clear, aqua-tint)
-40 to 180°F
(-40 to 82°C)
None95 (A)BDBBA 3956610.517.1
Polyurethane
(red, green,
blue, black)
-70 to 185°F
(-57 to 85°C)
None95 (A)BDBBA 3956610.517.1
PTFE-400 to 500°F
(-240 to 260°C)
FDA, USP, GMP50 (D)AAAAAA6.8  1.0
PTFE
color-coded
-400 to 500°F
(-240 to 260°C)
None50 (D)AAAAAA6.8  1.0
PVC10 to 140°F
(-12 to 60°C)
None65 (A)AAAAAA6.8  1.0
PVC Bubble®-5 to 180°F
(-21 to 82°C)
None55 (A)ADADBD1305 1345 
PVC food-grade10 to 140°F
(-12 to 60°C)
FDA, 3A, USDA65 (A)AAAAAA6.8  1.0
PVC reinforced-5 to 180°F
(-21 to 82°C)
FDA, USDA, NSF, 3A65 (A)ADAABD36 36 
PVC
wire-reinforced
25 to 150°F
(-4 to 65°C)
FDA, USDA, 3A, NSF70 (A)ADAABD36 36 
Silicone,
peroxide-cured
-60 to 460°F
(-51 to 238°C)
FDA, USP, GMP50 (A)BDAAA 20,132657979612763
Silicone,
platinum-cured
-60 to 460°F
(-51 to 238°C)
FDA, USP, USDA, GMP50 (A)BDAAA 20,132657979612763
Silicone
reinforced,
peroxide
-60 to 400°F
(-51 to 204°C)
FDA, USP, GMP60 (A)BDAAA 20,132657979612763
Stainless steel, 316-65 to 550°F
(-53 to 289°C)
None ABACAA    
Tygon®,
FEP-lined
-40 to 180°F
(-40 to 82°C)
FDA*, USP*, GMP67 (A)AAAABB5.9*1.3*14*2.0*
Tygon®
fuel/lubricant
-35 to 165°F
(-37 to 74°C)
GMP57 (A)BCCDAA100 1222
Tygon®
food/beverage
-49 to 165°F
(-45 to 74°C)
FDA, NSF, 3A63 (A)ABABBD270 3060
Tygon®
high-purity
-94 to 125°F
(-70 to 52°C)
FDA, USP, GMP72 (A)ACAABB745 13545
Tygon®
high-purity reinforced
-94 to 125°F
(-70 to 52°C)
FDA, NSF, GMP72 (A)ACAABB745 13545
Tygon®
lab; vacuum
-58 to 165°F
(-50 to 74°C)
FDA, GMP55 (A)ADADBD360 4080
Tygon®
LFL
-58 to 165°F
(-50 to 74°C)
FDA, USP, GMP56 (A)AAAB      
Tygon®
pressure
-47 to 165°F
(-44 to 74°C)
FDA, 3A, NSF65 (A)AABA  2700 600300
Tygon®
sanitary
silicone pres.
-112 to 320°F
(-51 to 160°C)
FDA, USP, NSF, GMP70 (A)BDAAA     
Tygon®
silicone
-112 to 392°F
(-80 to 200°C)
FDA, USP, NSF, GMP50 (A)ACAABB    
Tygon®
ultra
chemical-resistant
-108 to 125°F
(-78 to 52°C)
GMP72 (A)ACAABB4840 980350
Tygothane®
pressure
-100 to 180°F
(-73 to 82°C)
FDA, NSF82 (A)CCBDA 1680 18060
Vinyl-45 to 180°F
(-43 to 82°C)
GMP67 (A)ADAACD360 4080
Viton®-25 to 400°F
(-32 to 204°C)
GMP75 (A)AACDAA79 154.3

*Based on liner
†At 25°C
Bev-A-Line—Reg TM Thermoplastic Processes, Inc.
Bubble—Reg TM Sherwood Medical Industries Inc.
Chemfluor, Norprene, PharMed, Tygon, Tygothane—Reg TM Norton Performance Plastics Corp.
C-FLEX—Reg TM Consolidated Polymer Technologies, Inc.
Hypalon, Viton—Reg TM DuPont Dow Elastomers L.L.C.
Kynar, Superflex—Reg TM Elf Atochem North America

Pump tubing for a wide range of applications and markets

Pump tubing is used for a variety of applications and in a wide range of markets and industries such as:

  • Life Science Research Solutions, Products, and Resources
  • Chromatography and Mass Spectrometry
  • Analytical Chemistry
  • Biopharma Production
  • Safety
  • Controlled Environment and Cleanroom Solutions

All have trusted Masterflex® pump tubing for their specific needs. Visit our website or contact us for further information.

The tubing guide you need

Need more guidance on selecting peristaltic pump tubing? Our Masterflex® pump tubing selection guides can help: Learn more about matching peristaltic pump tubing to the fluid you plan to use.

We’re here to help you keep your research going. Contact us with any questions you have about pump tubing.