576 Results for: "trans-4-phenylcyclohexanecarboxylic acid"

Supplier: Bioss

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Supplier: Thermo Scientific Chemicals

Methyl crotonate all trans 98% (by GC), liquid

Supplier: Bioss

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Supplier: TCI America

CAS Number: 27829-72-7
MDL Number: MFCD00036541
Molecular Formula: C8H14O2
Molecular Weight: 142.20
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Boiling point (°C): 85
Flash Point (°C): 62
Specific Gravity (20/20): 0.90

Supplier: Enzo Life Sciences

Fatty acid synthase inhibitor

Supplier: MilliporeSigma

Sorbic acid, Cas number: 110-44-1, Synonyms: 2,4-Hexadienic acid, suitable for use as excipient EMPROVE* exp Ph Eur,BP,NF,FCC,E 200, 5 kg

Supplier: MilliporeSigma

A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity

Supplier: Prosci

HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.

Supplier: TCI America

CAS Number: 10236-16-5
Molecular Formula: C22H42O2
Molecular Weight: 338.58
Purity/Analysis Method: >88.0% (GC)
Form: Clear Liquid
Color: Colorless
Flash Point (°C): 184
Specific Gravity (20/20): 0.87

Supplier: TCI America

CAS Number: 118-56-9
Molecular Formula: C16H22O3
Molecular Weight: 262.35
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Color: Colorless
Boiling point (°C): 165
Specific Gravity (20/20): 1.05

Supplier: TCI America

CAS Number: 185855-30-5
Molecular Formula: C12H18O6
Molecular Weight: 258.27
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Color: Colorless
Specific Gravity (20/20): 1.20
Storage Temperature: 0-10°C

Supplier: TCI America

CAS Number: 7367-82-0
MDL Number: MFCD00015287
Molecular Formula: C10H18O2
Molecular Weight: 170.25
Purity/Analysis Method: >96.0% (GC)
Form: Clear Liquid
Boiling point (°C): 69
Flash Point (°C): 89
Specific Gravity (20/20): 0.89

Supplier: Thermo Scientific Chemicals

3-[4-(Acetylamino)phenyl]acrylic acid predominantly trans 98%

Supplier: Bioss

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Supplier: Enzo Life Sciences

Ultra-pure

Supplier: TCI America

CAS Number: 29275-88-5
MDL Number: MFCD00797465
Molecular Formula: C9H17NO2
Molecular Weight: 207.70
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal

Supplier: TCI America

CAS Number: 926905-71-7
Molecular Formula: C7H11NO4
Molecular Weight: 173.17
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Melting point (°C): 131
Specific rotation [a]20/D: -117 deg (C=4, H2O)

Supplier: TCI America

CAS Number: 4534-68-3
MDL Number: MFCD00070496
Molecular Formula: C8H10O8
Molecular Weight: 234.16
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal

Supplier: TCI America

CAS Number: 203866-14-2
MDL Number: MFCD06796085
Molecular Formula: C10H16FNO4
Molecular Weight: 233.24
Purity/Analysis Method: >96.0% (GC,T)
Form: Crystal
Melting point (°C): 116
Specific rotation [a]20/D: -69 deg (C=1, MeOH)

Supplier: MilliporeSigma

A natural dietary compound reported to have anticarcinogenic and anti-inflammatory properties. A selective, non-competitive inhibitor of 5-lipoxygenase (ID50=3.7µM). Inhibits Ca2+-induced LDL oxidation in the initiation phase but acts as a prooxidant in the propagation phase. An irreversible inhibitor of glutathione S-transferases and a non-competitive inhibitor of xanthine oxidase.

Supplier: Prosci

HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluidsHistidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.

Supplier: TCI America

CAS Number: 13726-69-7
MDL Number: MFCD00053370
Molecular Formula: C10H17NO5
Molecular Weight: 231.25
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Melting point (°C): 122
Specific rotation [a]20/D: -68 deg (C=1, MeOH)

Supplier: Bioss

This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011]

Supplier: Prosci

Cyclophilin C is an enzyme (EC 5.2.1.8) found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline. Proline has an unusually conformationally restrained peptide bond due to its cyclic structure with its side chain bonded to its secondary amine nitrogen. Most amino acids have a strong energetic preference for the trans peptide bond conformation due to steric hindrance, but prolines unusual structure stabilizes the cis form so that both isomers are populated under biologically relevant conditions. Proteins with prolyl isomerase activity include cyclophilin, FKBPs, and parvulin, although larger proteins can also contain prolyl isomerase domains.

Supplier: Prosci

Nectin-3 is a type I transmembrane glycoprotein that belongs to the nectin family. Its precursor is 549 amino acids in length and contains an extended signal sequence of 57 amino acids, an extracellular domain (ECD) of 347 amino acids, a transmembrane segment of 21 amino acids, and a cytoplasmic region of 124 amino acids. It is predominantly expressed in testis and placenta as well as in various cell lines, including epithelial cell lines. Nectin-3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/Nectin-2 at Sertoli-spermatid junctions. Nectin-3 is also involved in the formation of cell-cell junctions, including adherens junctions and synapses.

Supplier: MilliporeSigma

Potassium sorbate 99.0-101.0% (by acidimetry), EMPROVE® ESSENTIAL Ph. Eur., BP, NF, FCC, E202, SAFC®

Supplier: MilliporeSigma

(Vitamin A acid; tretinoin). Yellow-orange solid. PROTECT FROM LIGHT. HYGROSCOPIC. PACKAGED UNDER INERT GAS. PROTECT FROM AIR. Potent modulator of growth and differentiation.

Supplier: TCI America

CAS Number: 17351-22-3
Molecular Formula: C12H20O4
Molecular Weight: 228.29
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 104
Specific Gravity (20/20): 1.04

Supplier: Prosci

Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway.

Supplier: MilliporeSigma