14239 Results for: "trans-1,4-dichlorocyclohexa"

Supplier: Prosci

TIP47 Antibody: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.

Supplier: Restek

Contains: Benzene (71-43-2); Bromobenzene (108-86-1); Bromochloromethane (74-97-5); Bromodichloromethane (75-27-4); Bromoform (75-25-2); n-Butylbenzene (104-51-8); sec-Butylbenzene (135-98-8); tert-Butylbenzene (98-06-6); Carbon tetrachloride (56-23-5); Chlorobenzene (108-90-7); Chloroform (67-66-3); 2-Chlorotoluene (95-49-8); 4-Chlorotoluene (106-43-4); Dibromochloromethane (124-48-1); 1,2-Dibromo-3-chloropropane (DBCP) (96-12-8); 1,2-Dibromoethane (EDB) (106-93-4); Dibromomethane (74-95-3); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); 1,1-Dichloroethane (75-34-3); 1,2-Dichloroethane (107-06-2); 1,1-Dichloroethene (75-35-4); cis-1,2-Dichloroethene (156-59-2); trans-1,2-Dichloroethene (156-60-5); 1,2-Dichloropropane (78-87-5); 1,3-Dichloropropane (142-28-9); 2,2-Dichloropropane (594-20-7); 1,1-Dichloropropene (563-58-6); cis-1,3-Dichloropropene (10061-01-5); trans-1,3-Dichloropropene (10061-02-6); Ethylbenzene (100-41-4); Hexachloro-1,3-butadiene (hexachlorobutadiene) (87-68-3); Isopropylbenzene (cumene) (98-82-8); 4-Isopropyltoluene (p-cymene) (99-87-6); Methylene chloride (dichloromethane) (75-09-2); Naphthalene (91-20-3); n-Propylbenzene (103-65-1); Styrene (100-42-5); 1,1,1,2-Tetrachloroethane (630-20-6); 1,1,2,2-Tetrachloroethane (79-34-5); Tetrachloroethene (127-18-4); Toluene (108-88-3); 1,2,3-Trichlorobenzene (87-61-6); 1,2,4-Trichlorobenzene (120-82-1); 1,1,1-Trichloroethane (71-55-6); 1,1,2-Trichloroethane (79-00-5); Trichloroethene (79-01-6); 1,2,3-Trichloropropane (96-18-4); 1,2,4-Trimethylbenzene (95-63-6); 1,3,5-Trimethylbenzene (108-67-8); m-Xylene (108-38-3); o-Xylene (95-47-6); p-Xylene (106-42-3)

Supplier: Prosci

TIP47 Antibody: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.

Supplier: Thermo Scientific Chemicals

1,2-Diphenylcyclopropane cis- and trans- mixture 97%

Supplier: Restek

Contains: 30042: 502.2 Calibration Mix #1 (gases); Bromomethane (methyl bromide) (74-83-9); Chloroethane (ethyl chloride) (75-00-3); Chloromethane (methyl chloride) (74-87-3); Dichlorodifluoromethane (CFC-12) (75-71-8); Trichlorofluoromethane (CFC-11) (75-69-4); Vinyl chloride (75-01-4);30431: 502.2 MegaMix Standard; Benzene (71-43-2); Bromobenzene (108-86-1); Bromochloromethane (74-97-5); Bromodichloromethane (75-27-4); Bromoform (75-25-2); n-Butylbenzene (104-51-8); sec-Butylbenzene (135-98-8); tert-Butylbenzene (98-06-6); Carbon tetrachloride (56-23-5); Chlorobenzene (108-90-7); Chloroform (67-66-3); 2-Chlorotoluene (95-49-8); 4-Chlorotoluene (106-43-4); Dibromochloromethane (124-48-1); 1,2-Dibromo-3-chloropropane (DBCP) (96-12-8); 1,2-Dibromoethane (EDB) (106-93-4); Dibromomethane (74-95-3); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); 1,1-Dichloroethane (75-34-3); 1,2-Dichloroethane (107-06-2); 1,1-Dichloroethene (75-35-4); cis-1,2-Dichloroethene (156-59-2); trans-1,2-Dichloroethene (156-60-5); 1,2-Dichloropropane (78-87-5); 1,3-Dichloropropane (142-28-9); 2,2-Dichloropropane (594-20-7); 1,1-Dichloropropene (563-58-6); cis-1,3-Dichloropropene (10061-01-5); trans-1,3-Dichloropropene (10061-02-6); Ethylbenzene (100-41-4); Hexachloro-1,3-butadiene (hexachlorobutadiene) (87-68-3); Isopropylbenzene (cumene) (98-82-8); 4-Isopropyltoluene (p-cymene) (99-87-6); Methylene chloride (dichloromethane) (75-09-2); Naphthalene (91-20-3); n-Propylbenzene (103-65-1); Styrene (100-42-5); 1,1,1,2-Tetrachloroethane (630-20-6); 1,1,2,2-Tetrachloroethane (79-34-5); Tetrachloroethene (127-18-4); Toluene (108-88-3); 1,2,3-Trichlorobenzene (87-61-6); 1,2,4-Trichlorobenzene (120-82-1); 1,1,1-Trichloroethane (71-55-6); 1,1,2-Trichloroethane (79-00-5); Trichloroethene (79-01-6); 1,2,3-Trichloropropane (96-18-4); 1,2,4-Trimethylbenzene (95-63-6); 1,3,5-Trimethylbenzene (108-67-8); m-Xylene (108-38-3); o-Xylene (95-47-6); p-Xylene (106-42-3)

Supplier: Prosci

GOLPH3 Antibody: GOLPH3 was initially identified as a peripheral membrane protein localized to the trans-Golgi network, but others reported it to be primarily a mitochondrial protein that regulated the mitochondrial mass through the regulation of the mitochondria-specific phospholipid cardiolipin. GOLPH3 has since been implicated in the target of rapamycin (TOR) signalling pathway. Its overexpression in transfected cells led to and increase in anchorage-independent growth and cell proliferation in vitro. Furthermore, GOLPH3-transfected cells enhanced S6 Kinase activity in response to growth factor stimulation by EGF. Simultaneously, AKT phosphorylation increased in these cells, while these events were abrogated in GOLPH3 siRNA treated cells compared to control cells, indicating the GOLPH3 can enhance signalling through TOR-associated complexes. These results suggest that GOLPH3 is a bona fide oncogene and may be a useful target for therapeutic strategies.

Supplier: Thermo Scientific Chemicals

Triethyl-4-phosphonocrotonate cis- and trans- mixture 94%

Supplier: Restek

Contains: 30439: 502.2 Calibration Mix #1 (gases); Bromomethane (methyl bromide) (74-83-9); Chloroethane (ethyl chloride) (75-00-3); Chloromethane (methyl chloride) (74-87-3); Dichlorodifluoromethane (CFC-12) (75-71-8); Trichlorofluoromethane (CFC-11) (75-69-4); Vinyl chloride (75-01-4);30432: 502.2 MegaMix Standard; Benzene (71-43-2); Bromobenzene (108-86-1); Bromochloromethane (74-97-5); Bromodichloromethane (75-27-4); Bromoform (75-25-2); n-Butylbenzene (104-51-8); sec-Butylbenzene (135-98-8); tert-Butylbenzene (98-06-6); Carbon tetrachloride (56-23-5); Chlorobenzene (108-90-7); Chloroform (67-66-3); 2-Chlorotoluene (95-49-8); 4-Chlorotoluene (106-43-4); Dibromochloromethane (124-48-1); 1,2-Dibromo-3-chloropropane (DBCP) (96-12-8); 1,2-Dibromoethane (EDB) (106-93-4); Dibromomethane (74-95-3); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); 1,1-Dichloroethane (75-34-3); 1,2-Dichloroethane (107-06-2); 1,1-Dichloroethene (75-35-4); cis-1,2-Dichloroethene (156-59-2); trans-1,2-Dichloroethene (156-60-5); 1,2-Dichloropropane (78-87-5); 1,3-Dichloropropane (142-28-9); 2,2-Dichloropropane (594-20-7); 1,1-Dichloropropene (563-58-6); cis-1,3-Dichloropropene (10061-01-5); trans-1,3-Dichloropropene (10061-02-6); Ethylbenzene (100-41-4); Hexachloro-1,3-butadiene (hexachlorobutadiene) (87-68-3); Isopropylbenzene (cumene) (98-82-8); 4-Isopropyltoluene (p-cymene) (99-87-6); Methylene chloride (dichloromethane) (75-09-2); Naphthalene (91-20-3); n-Propylbenzene (103-65-1); Styrene (100-42-5); 1,1,1,2-Tetrachloroethane (630-20-6); 1,1,2,2-Tetrachloroethane (79-34-5); Tetrachloroethene (127-18-4); Toluene (108-88-3); 1,2,3-Trichlorobenzene (87-61-6); 1,2,4-Trichlorobenzene (120-82-1); 1,1,1-Trichloroethane (71-55-6); 1,1,2-Trichloroethane (79-00-5); Trichloroethene (79-01-6); 1,2,3-Trichloropropane (96-18-4); 1,2,4-Trimethylbenzene (95-63-6); 1,3,5-Trimethylbenzene (108-67-8); m-Xylene (108-38-3); o-Xylene (95-47-6); p-Xylene (106-42-3)

Supplier: Prosci

GOLPH3 Antibody: GOLPH3 was initially identified as a peripheral membrane protein localized to the trans-Golgi network, but others reported it to be primarily a mitochondrial protein that regulated the mitochondrial mass through the regulation of the mitochondria-specific phospholipid cardiolipin. GOLPH3 has since been implicated in the target of rapamycin (TOR) signalling pathway. Its overexpression in transfected cells led to and increase in anchorage-independent growth and cell proliferation in vitro. Furthermore, GOLPH3-transfected cells enhanced S6 Kinase activity in response to growth factor stimulation by EGF. Simultaneously, AKT phosphorylation increased in these cells, while these events were abrogated in GOLPH3 siRNA treated cells compared to control cells, indicating the GOLPH3 can enhance signalling through TOR-associated complexes. These results suggest that GOLPH3 is a bona fide oncogene and may be a useful target for therapeutic strategies.

Supplier: Prosci

EVER1 Antibody: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes, EVER1 and EVER2, located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family. EVER1 possesses eight trans-membrane domains and two leucine zipper motifs. EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1), suggesting that EVER1 and EVER2 act to regulate cellular zinc balance.

Supplier: Prosci

Serine/threonine-protein kinase that converts transient diacylglycerol
(DAG) signals into prolonged physiological effects downstream of PKC, and is involved in
the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and
trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation
by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling,
and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced
apoptosis and flagellin-stimulated inflammatory response. Phosphorylates the epidermal
growth factor receptor (EGFR) on dual threonine residues, which leads to the
suppression of epidermal growth factor (EGF)-induced MAPK8/JNK1 activation and
subsequent JUN phosphorylation. Phosphorylates RIN1, inducing RIN1 binding to 14-3-3
proteins YWHAB, YWHAE and YWHAZ and increased competition with RAF1 for binding
to GTP-bound form of Ras proteins (NRAS, HRAS and KRAS). Acts downstream of the
heterotrimeric G-protein beta/gamma-subunit complex to maintain the structural
integrity of the Golgi membranes, and is required for protein transport along the
secretory pathway. In the trans-Golgi network (TGN), regulates the fission of transport
vesicles that are on their way to the plasma membrane. May act by activating the lipid
kinase phosphatidylinositol 4-kinase beta (PI4KB) at the TGN for the local synthesis of
phosphorylated inositol lipids, which induces a sequential production of DAG,
phosphatidic acid (PA) and lyso-PA (LPA) that are necessary for membrane fission and
generation of specific transport carriers to the cell surface. Under oxidative stress, is
phosphorylated at Tyr-463 via SRC-ABL1 and contributes to cell survival by activating IKK
complex and subsequent nuclear translocation and activation of NFKB1. Involved in cell
migration by regulating integrin alpha-5/beta-3 recycling and promoting its recruitment
in newly forming focal adhesion.

Supplier: Thermo Scientific Chemicals

Diethyl fumarate 98%

Supplier: Thermo Scientific Chemicals

MDL: MFCD00064438 Beilstein Registry No.: 774590

Supplier: VWR International

Application specific highly polar phase, ideal for detailed cis/trans FAMEs separation.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

For Laboratory,Research,or Manufacturing Use

Supplier: VWR International

VWR® static-shielding reclosable bags provide total Faraday Cage protection and visibility for highly sensitive electronic components.

Supplier: TCI America

CAS Number: 155041-85-3
MDL Number: MFCD12911573
Molecular Formula: C21H30
Molecular Weight: 282.47
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 66

Supplier: Thermo Scientific Chemicals

trans,trans-Dibenzylideneacetone 98+%

Supplier: Thermo Scientific Chemicals

trans-3-Cyanocyclohexylamine hydrochloride, 97%

Supplier: MilliporeSigma

Trans-Stilbene, CAS Number: 103-30-0, Synonyms: trans-1,2-Diphenylethylene, Chemical formula: C6H5CH=CHC6H5, for synthesis.

Supplier: TCI America

CAS Number: 501-98-4
MDL Number: MFCD00004399
Molecular Formula: C9H8O3
Molecular Weight: 164.16
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 213

Supplier: TCI America

CAS Number: 103-30-0
MDL Number: MFCD00064300
Molecular Formula: C14H12
Molecular Weight: 180.25
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Color: White
Boiling point (°C): 307
Melting point (°C): 123

Supplier: Thermo Scientific Chemicals

Trans-2-(Benzyloxycarbonylamino)cyclohexanecarboxylic acid, Purity: 97%, CAS Number: 61935-48-6, Molecular Formula: C15H19NO4, Synonym: Z-1, 2-trans-ACHC-OH, Z-trans-2-aminocyclohexanecarboxylic acid, Size: 5G

Supplier: TCI America

CAS Number: 2566-97-4
MDL Number: MFCD00069997
Molecular Formula: C19H34O2
Molecular Weight: 294.48
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 152
Specific Gravity (20/20): 0.88
Storage Temperature: <0°C

Supplier: Thermo Scientific Chemicals

(±)-trans-1,2-Diaminocyclohexane 99%

Supplier: TCI America

CAS Number: 1694-20-8
MDL Number: MFCD00053614
Molecular Formula: C14H11NO2
Molecular Weight: 225.25
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 157

Supplier: Thermo Scientific Chemicals

trans-4-Cyanocyclohexylamine hydrochloride, 97%

Supplier: TCI America

CAS Number: 25152-84-5
MDL Number: MFCD00007007
Molecular Formula: C10H16O
Molecular Weight: 152.24
Purity/Analysis Method: >90.0% (GC)
Form: Clear Liquid
Boiling point (°C): 116
Flash Point (°C): 100
Specific Gravity (20/20): 0.87

Supplier: Thermo Scientific Chemicals

trans-2-Aminocyclohexanol hydrochloride 98+%

Supplier: Thermo Scientific Chemicals

trans,trans-2,4-Hexadienal predominantly trans 95%