19626 Results for: "small b30.2"

Supplier: ABCAM INC CA

Highly potent, selective, competitive, non-peptide CCK1 receptor antagonist (Ki = 0.2 nM). Increases plasma leptin levels. Shows central effects. Stimulates food intake *in vivo.* Orally active.

Supplier: ABCAM INC CA

Potent, selective sphingosine-1-phosphate (S1P1) agonist (EC50 =13 nM). Does not activate S1P2, S1P3, S1P4 or S1P5 receptors. Cell-permeable and active in vivo.

Supplier: ABCAM INC CA

Selective cell-permeable inhibitor of casein kinase 1 (CK1). (IC₅₀ values are 0.3 (CK1), 0.5 (ALK5), 9.1 (PKd1) and 5.8 μM (p38αMAPK)). Displays selectivity over many other protein kinases.

Supplier: ABCAM INC CA

Cell-permeable definitive endoderm formation inducer (EC₅₀ = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1. Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo.

Supplier: ABCAM INC CA

Endogenous sleep-inducing lipid. Increases cytosolic free Ca²+ concentration (EC₅₀ = 20 μM). Centrally active. Crosses the blood-brain barrier. Inhibits cholesterol-induced atherosclerosis in vivo. Orally active.

Supplier: ABCAM INC CA

pH indicator (pH 9.4 - 14.0). Achieve your results faster with highly validated, pure and trusted compounds.

Supplier: ABCAM INC CA

Diacetate derivative of rose bengal with greatly improved membrane permeability, allowing it to accumulate intracellularly where esterase activity releases the active rose bengal photosensitizer. Activation with UV light at 561 nm causes singlet oxygen production and photosensitization.

Supplier: ABCAM INC CA

Ribonucleoside (Uridine ab143255) analog. Antisense agent. RNA synthesis inhibitor. Modifies oligos slated for RNA. Induces p53 and inhibits proliferation. Metabolically labels RNA for stability studies.

Supplier: ABCAM INC CA

Pyrimidine nucleoside triphosphate. Precursor in the enzymatic biosynthesis of RNA. P2Y receptor agonist, used to study ion transport functions of P2Y2 receptors on rat basolateral membranes.

Supplier: ABCAM INC CA

Ultrasensitive fluorogenic β-glucosidase substrate. Releases fluorescent dye fluorescein (Ex/Em =490/514 nm) in direct correlation with enzyme activity in vivo or in vitro. Used for quantification of enzyme activity and cell viability determination.

Supplier: ABCAM INC CA

Thymidine analogue, readily incorporated following phosphorylation, into newly synthesized DNA in place of thymidine. Used to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors.

Supplier: ABCAM INC CA

Potent α-glycosidase inhibitor (IC₅₀ = 30 nM). Antihyperglycemic agent. Downregulates SGLT1, Na⁺/K+-ATP and GLUT2 expression. Decreases MCP-1 and TNF-α levels. Shows antidiabetic, antiviral, antiobesity and anti-inflammatory effects in vivo. Orally active.

Supplier: ABCAM INC CA

Endogenous signaling sphingolipid and agonist of S1P receptors (EDG-GPCRs). Mobilises Ca²⁺ from intracellular stores via IP3 receptor independent pathways. Activates MAPK pathways. Regulates a variety of cellular responses and promotes angiogenesis.

Supplier: ABCAM INC CA

Potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC₅₀ values are 220 and 150 nM, respectively). Binds with high affinity to serum albumin.

Supplier: Abcam

Topoisomerase I and II inhibitor (IC₅₀ = 100 μM). Potent DNA gyrase inhibitor. Antibiotic agent. Inhibits topoisomerase II without inducing DNA strands breaks. Shows antiproliferative effects against cancer cell lines (IC₅₀ values are 75-125 μM for NSCLC cells).

Supplier: ABCAM INC CA

Highly sensitive lactosidase, yellow coloured probe that releases the product 2-chloro-4-nitrophenol (CNP). Can be monitored spectrophotometrically at 405 nm. The rate of formation of 2-chloro-4-nitrophenol is directly proportional to the lactosidase activity in the sample. The pKa of CNP is approximately 5.5.

Supplier: ABCAM INC CA

Long chain polyunsaturated fatty acid. Used in fatty acid studies and as internal standard.

Supplier: Genetex

Rabbit Polyclonal antibody to DUSP12 (dual specificity phosphatase 12)

Supplier: Edvotek

For AP Biology Classes

Supplier: Thermo Fisher Scientific

These durable pumps easily and quickly attain and hold vacuum of 635Torr (25" Hg)

Supplier: Antibodies.com

Mouse monoclonal [SN3] antibody to CD24 (APC-Cyanine 7) for Flow Cytometry with samples derived from Human.

Supplier: General Glass Blowing

The apparatus incorporates aeration-oxidation (Vacuum aspiration) method, in which a stream of air is passed through an acidified wine sample carrying released SO₂ through a condenser into a hydrogen peroxide trapping solution containing acid/base indicator. Precision of the analysis is dependent largely upon thorough consistent aeration and subsequent efficient trapping in the H₂O₂ solution.

Supplier: Lakeside

Stainless steel carts features fully welded construction, exterior push handles for better control, and more interior space

Supplier: Sklar

Econo™ Sterile Hartmann Mosquito Forceps are used as both a hemostat and for fine tissue dissection in shallow wounds and procedures

Supplier: VWR International

VWR® Maximum Protection Non-Skid Shoe Covers are the cleanest and most durable within the entire VWR Protection line of apparel

Supplier: VWR International

Pump system automatically adjusts speed to maintain set pressure.

Supplier: Thermo Fisher Scientific

Measure dissolved oxygen as percent saturation, concentration in mg/L or concentration in ppm simultaneously with temperature using the Orion™ Lab Star DO113 DO bench meter.

Supplier: DENIOS INC

SPILL PALLET K22 15012 DRUM SPILL CON

Supplier: Skywill Far East Industries

Give your students the hands-on experience of working with these wooden shapes to explore geometric principles.

Supplier: Proteintech

Anti-TMEM41A Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Fusion Protein, 1-80 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, Recommended Storage: - 20 C or lower