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1375 results for "purpura (1,2,4-Trihydroxy-9,10-anthraquinone)"

1375 Results for: "purpura (1,2,4-Trihydroxy-9,10-anthraquinone)"

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Elite ESD Chairs

Elite ESD Chairs

Supplier: BioFit

Elite Series chairs boast a number of ergonomic features and benefits that make them a popular choice for laboratory, healthcare, education, and technical workspaces. The ergonomic design enhances user comfort and productivity when sitting for prolonged periods.

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Flotation Work Stations™, Low Profile, TBS®

Flotation Work Stations™, Low Profile, TBS®

Supplier: General Data Healthcare

Equip your lab with a TBS® Flotation Bath and make your tissue preparation easier, safer and more efficient

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SP Bel-Art Secador® 1.0, 2.0, 3.0, 4.0 Vertical Desiccator Cabinets, Bel-Art Products, a part of SP

SP Bel-Art Secador® 1.0, 2.0, 3.0, 4.0 Vertical Desiccator Cabinets, Bel-Art Products, a part of SP

Supplier: Bel-Art Products, a Part of SP

The attractive design and sturdy construction of the Secador® line of desiccator cabinets assures easy and reliable storage of moisture- and light-sensitive products.

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Micro/Mini-Lab Kit, Deluxe Kits, Ace Glass Incorporated

Micro/Mini-Lab Kit, Deluxe Kits, Ace Glass Incorporated

Supplier: Ace Glass

This is a Deluxe Micro/Mini-Lab Kit for performing all of the experiments in Organic Laboratory Techniques.

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Digital Orbital Shaker

Digital Orbital Shaker

Supplier: Heathrow Scientific

Versatile shaker for a vast range of protocols. Create own matrix for vessels of all shapes and sizes with Hi-Lo platform and bungee cords.

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AlphaTec™ 56-100 Heavy-Duty PVC Aprons, Ansell

Supplier: Ansell Healthcare

These heavy-duty PVC aprons feature 18-millimeter die-cut PVC and offer users a combination of chemical splash protection and flexible comfort.

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Tygon S3™ B-44-3 Beverage Tubing, Saint-Gobain Life Sciences

Tygon S3™ B-44-3 Beverage Tubing, Saint-Gobain Life Sciences

Supplier: Saint Gobain Life Sciences

Tygon S3™ B-44-3 Beverage Tubing from Saint-Gobain Performance Plastics is now phthalate-free.

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UVP Compact and Handheld Lamps, Analytik Jena

UVP Compact and Handheld Lamps, Analytik Jena

Supplier: Analytik Jena US

UVP Compact and Handheld Ultraviolet Lamps use UV wavelengths which are an essential multipurpose tools for laboratory applications. The lamps are lightweight and ergonomically designed for handheld use.

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Biotix Disposable Reagent Reservoirs, Biotix

Biotix Disposable Reagent Reservoirs, Biotix

Supplier: Biotix

Biotix disposable reagent reservoirs are designed for use in multi-channel pipetting applications and can accommodate up to 12-channel pipettors. Angled sides and a V-shaped bottom allow for maximum recovery of reagents. All reservoirs feature internal graduated volume lines and pour-spouts on the corners. Choose from opaque white polyvinyl chloride (PVC) or high clarity polystyrene (PS) in several packaging configurations.

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Anti-LRDD Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Supplier: Bioss

The death domain (DD) containing protein PIDD is a p53 target gene in an erythroleukemia cell line that undergoes G1 phase arrest and subsequent apoptosis after p53 expression. Independently, PIDD was also described as a DD-containing protein with unknown function. The N-terminal region of PIDD contains seven leucine-rich repeats (LRRs), a protein interaction motif found in various proteins with diverse functions, followed by two ZU-5 domains and a C-terminal DD. PIDD forms a complex with caspase-2 and the adaptor protein RAIDD. Increased PIDD expression results in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli, via interaction with caspase-2 and CRADD/RAIDD. PIDD also promotes apoptosis downstream of p53 as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. PIDD has also been shown to interact with NEMO/IKBKG and RIP1 and enhance sumoylation and ubiquitination of NEMO/IKBKG, an important component for activation of the transcription factor NF-kappa-B.

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BioFit Bridgeport Cleanroom Swivel Chairs, ISO 5

BioFit Bridgeport Cleanroom Swivel Chairs, ISO 5

Supplier: BioFit

Bridgeport Series chairs boast a number of features and benefits that make them a popular choice for laboratory, healthcare, education, technical, industrial and office workspaces. The ergonomic design enhances user comfort and productivity when sitting for prolonged periods.

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Anti-TEM5 Rabbit Polyclonal Antibody

Anti-TEM5 Rabbit Polyclonal Antibody

Supplier: Prosci

TEM5 Antibody: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.

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AlphaTec™ 56-101 Heavy-Duty PVC Aprons, Ansell

Supplier: Ansell Healthcare

These heavy-duty PVC aprons feature 18-millimeter die-cut PVC and offer users a combination of chemical splash protection and flexible comfort.

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Anti-GPR124 Rabbit Polyclonal Antibody

Anti-GPR124 Rabbit Polyclonal Antibody

Supplier: Prosci

TEM5 Antibody: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.

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Anti-GPR124 Rabbit Polyclonal Antibody

Anti-GPR124 Rabbit Polyclonal Antibody

Supplier: Prosci

TEM5 Antibody: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.

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Anti-TEM5 Rabbit Polyclonal Antibody

Anti-TEM5 Rabbit Polyclonal Antibody

Supplier: Prosci

TEM5 Antibody: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.

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Anti-LRDD Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Supplier: Bioss

The death domain (DD) containing protein PIDD is a p53 target gene in an erythroleukemia cell line that undergoes G1 phase arrest and subsequent apoptosis after p53 expression. Independently, PIDD was also described as a DD-containing protein with unknown function. The N-terminal region of PIDD contains seven leucine-rich repeats (LRRs), a protein interaction motif found in various proteins with diverse functions, followed by two ZU-5 domains and a C-terminal DD. PIDD forms a complex with caspase-2 and the adaptor protein RAIDD. Increased PIDD expression results in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli, via interaction with caspase-2 and CRADD/RAIDD. PIDD also promotes apoptosis downstream of p53 as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. PIDD has also been shown to interact with NEMO/IKBKG and RIP1 and enhance sumoylation and ubiquitination of NEMO/IKBKG, an important component for activation of the transcription factor NF-kappa-B.

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Cubis® II Advanced Analytical Laboratory Balances, MCA Series, Standard Version, Sartorius

Cubis® II Advanced Analytical Laboratory Balances, MCA Series, Standard Version, Sartorius

Supplier: Sartorius

These Cubis® II laboratory balances are ideal for high-performance portfolio of both lab weighing hardware and software.

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Protector® Workstations, Labconco®

Protector® Workstations, Labconco®

Supplier: Labconco

Designed for the needs of histologists and pathologists, these workstations rid the lab of dangerous organic solvent fumes, such as formaldehyde and xylene, and restore clean air

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Semivolatile Calibration Kit #3 (with Benzidine), Restek

Semivolatile Calibration Kit #3 (with Benzidine), Restek

Supplier: Restek

Contains 1 ml each of the following mixtures, SV calibration mix #1 (anilines), SV calibration mix #2 (phenols), SV calibration mix #3 (base neutrals), SV calibration mix #4 (base neutrals), SV calibration mix #5 (PAHs), SV calibration mix #7 (dichlorobenzenes) and 605 benzidines calibration mix (benzidine and 3,3'-dichlorobenzidine).

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Masterflex® Ismatec® Reglo Gear Pump Systems with MasterflexLive®, Avantor®

Masterflex® Ismatec® Reglo Gear Pump Systems with MasterflexLive®, Avantor®

Supplier: Avantor Fluid Handling

Achieve high pressure and accurate, pulseless flow - with a secure, cloud-enabled platform for monitoring.

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8270 Calibration Kit, Restek

8270 Calibration Kit, Restek

Supplier: Restek

Contains 1 ml each of the followig mixtures, 8270 calibration mix #1, 8270 calibration mix #2, 8270 calibration mix #3, 8270 calibration mix #4, 8270 calibration mix #5 revised and 3-methylcholanthrene standard.

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Anti-MSH6 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Supplier: Bioss

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.

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Anti-MSH6 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Supplier: Bioss

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.

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GFX 96 PCR Purification Kit, Cytiva

GFX 96 PCR Purification Kit, Cytiva

Supplier: Cytiva

The illustra™ GFX™ 96 Purification Kit utilises glass fibre matrix technology in a 96-well format for highly efficient purification of PCR products. Fragments from PCR are captured by the matrix in the presence of a chaotropic salt, and contaminants are conveniently removed by washing the matrix with a buffered ethanol solution.

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