89195 Results for: "each (6-Maleimidohexanoic acid N-hydroxysuccinimide ester)"

Supplier: G-Biosciences

N-(ε-Maleimidocaproyloxy) succinimide ester Heterobifunctional Cross Linker.

Supplier: TCI America

[Cross-linking Reagent]
CAS Number: 55750-63-5
MDL Number: MFCD00043043
Molecular Formula: C14H16N2O6
Molecular Weight: 308.29
Purity/Analysis Method: >98.0% (N)
Form: Crystal
Color: White
Melting point (°C): 71
Storage Temperature: 0-10°C

Supplier: Thermo Scientific

Thermo Scientific Pierce EMCS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length spacer arm (9.4 angstroms).

Supplier: Thermo Scientific

Thermo Scientific Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

Supplier: Thermo Scientific

Thermo Scientific Pierce DSP (Lomant's Reagent) is a water-insoluble, homo-bifunctional N-hydroxysuccimide ester (NHS ester) crosslinker that is thiol-cleavable, primary amine-reactive, and useful for many applications. DSP contains an amine-reactive NHS ester at each end of an 8-carbon spacer arm. NHS esters react with primary amines at pH 7–9 to form stable amide bonds and releasing N-hydroxy-succinimide. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for NHS ester crosslinking reagents. DSP is non-sulfonated and insoluble in water, so it must first be dissolved in an organic solvent and then added to the aqueous reaction mixture. Because DSP does not possess a charged group, it is lipophilic and membrane-permeable and so useful for intracellular and intramembrane conjugation. A sulfonated analog of DSP (DTTSP) is water soluble. DSS, the non-cleavable analog of the DSP crosslinker is also available for applications that require a stable spacer arm that cannot be cleaved in the presence of reducing agents.

Supplier: G-Biosciences

Ethylene glycol bis(succinimidyl succinate) Homobifunctional Cross Linker.

Supplier: Thermo Scientific

Thermo Scientific Pierce DTSSP is a popular water-soluble crosslinker that contains amine-reactive NHS-ester ends around an 8-atom spacer arm, whose central disulfide bond can be cleaved with reducing agents.

Supplier: Thermo Scientific Chemicals

2,2,5,5-Tetramethyl-3-pyrrolin-1-oxyl-3-carboxylic acid-N-hydroxysuccinimide ester ≥98%

Supplier: TCI America

[Cross-linking Reagent]
CAS Number: 58626-38-3
MDL Number: MFCD00005514
Molecular Formula: C15H10N2O6
Molecular Weight: 314.25
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Color: White
Melting point (°C): 181
Storage Temperature: 0-10°C

Supplier: TCI America

CAS Number: 14464-29-0
MDL Number: MFCD00037916
Molecular Formula: C6H7NO4
Molecular Weight: 157.13
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Color: White
Melting point (°C): 134
Storage Temperature: 0-10°C

Supplier: Thermo Scientific

Thermo Scientific Pierce BMPS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (5.9 Å).

Supplier: Thermo Scientific Chemicals

A heterobifunctional coupling reagent useful for forming enzyme immunoconjugates

Supplier: TCI America

CAS Number: 68528-80-3
MDL Number: MFCD00049059
Molecular Formula: C16H20N2O8
Molecular Weight: 368.34
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 171

Supplier: TCI America

[Cross-linking Reagent]
CAS Number: 57757-57-0
MDL Number: MFCD00042045
Molecular Formula: C14H16N2O8S2
Molecular Weight: 404.41
Purity/Analysis Method: >97.0% (N)
Form: Crystal
Melting point (°C): 133
Storage Temperature: 0-10°C

Supplier: Thermo Scientific

Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

Supplier: G-Biosciences

Ideal for hapten-carrier protein, toxin-antibody, enzyme-antibody crosslinking

Supplier: TCI America

CAS Number: 64987-85-5
MDL Number: MFCD00009634
Molecular Formula: C16H18N2O6
Molecular Weight: 334.33
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Color: White
Melting point (°C): 177
Storage Temperature: <0°C

Supplier: TCI America

[Cross-linking Reagent]
CAS Number: 80307-12-6
MDL Number: MFCD00036817
Molecular Formula: C12H12N2O6
Molecular Weight: 280.24
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Color: White
Melting point (°C): 130
Storage Temperature: 0-10°C

Supplier: Thermo Scientific

Thermo Scientific Pierce MBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short aromatic spacer arm (7.3 angstroms).

Supplier: Thermo Scientific Chemicals

Powder

Supplier: TCI America

CAS Number: 92921-24-9
MDL Number: MFCD00054978
Molecular Formula: C16H18N2O9S
Molecular Weight: 436.37
Form: Crystal
Color: White
Storage Temperature: <0°C

Supplier: G-Biosciences

N-γ-Maleimidobutyryloxysuccinimide ester Heterobifunctional Cross Linker

Supplier: G-Biosciences

Ideal for enzyme-antibody crosslinking.

Supplier: Thermo Scientific

Thermo Scientific Pierce BS3 (Sulfo-DSS) is bis(sulfosuccinimidyl)suberate, an amine-to-amine crosslinker that is homobifunctional, water-soluble, non-cleavable and membrane impermeable.

Supplier: Thermo Scientific

Thermo Scientific Pierce Premium Grade Sulfo-SMCC is our highest quality formulation of amine-to-sulfhydryl crosslinker, specially characterized for applications where product integrity and risk minimization are paramount.

Supplier: Thermo Scientific

Thermo Scientific Pierce SIA is a very short (1.5 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.

Supplier: Thermo Scientific

Thermo Scientific Pierce SIAB is a mid-length (10.6 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.

Supplier: Thermo Scientific

Thermo Scientific Pierce Sulfo-SMCC, No-Weigh Format is a water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 angstroms).

Supplier: Thermo Scientific

Thermo Scientific EZ-Link Sulfo-NHS-SS-Biotin is a water-soluble, NHS-ester biotinylation reagent whose spacer arm includes a cleavable disulfide bond for reversible labeling of proteins and cell surface primary amines.

Supplier: Thermo Scientific

Thermo Scientific EZ-Link Sulfo-NHS-LC-Biotin is an intermediate-length, water-soluble biotinylation reagent for labeling antibodies, proteins and other molecules that have primary amines.