Order Entry
Canada
ContactUsLinkComponent
2714 results for "Shenandoah Biotechnology"

2714 Results for: "Shenandoah Biotechnology"

Sort By
Human Recombinant IL-16 (from E. coli)

Human Recombinant IL-16 (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interleukin 16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophils, dendritic cells, and Langerhans cells. Additionally, IL-16 upregulates the expression of the interleukin 2 receptor (CD25), modulates T lymphocyte growth, and suppresses the replication of the human immunodeficiency virus (HIV) and simian immunodeficiency viruses (SIV).

Expand 4 Items
Loading...
Mouse Recombinant IP-10  (from E. coli)

Mouse Recombinant IP-10 (from E. coli)

Supplier: Fujifilm Irvine Scientific

Macrophage inflammatory protein-1 alpha (MIP-1 α), also known as CCL3, is a cytokine produced by macrophages. MIP-1 α binds the chemokine receptors CCR1, CCR4, and CCR5 to induce inflammatory responses, including the recruitment of granulocytes and neutrophil superoxide production. The MIP-1 α and MIP-1 β heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).

Expand 5 Items
Loading...
Mouse Recombinant IGF-I (from E. coli)

Mouse Recombinant IGF-I (from E. coli)

Supplier: Fujifilm Irvine Scientific

Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a critical role in the maintenance, survival, and differentiation of hematopoietic stem cells. While human SCF shows no activity on murine cells, murine and rat SCF are active on human cells.

Expand 5 Items
Loading...
Mouse Recombinant SDF-1 A  (from E. coli)

Mouse Recombinant SDF-1 A (from E. coli)

Supplier: Fujifilm Irvine Scientific

Macrophage inflammatory protein-3 alpha (MIP-3 α), also called CCL20, is expressed in the liver, lungs, lymph nodes, and peripheral blood lymphocytes. MIP-3 α expression is strongly induced by inflammatory signals, and downregulated by the anti-inflammatory cytokine interleukin 10 (IL-10). MIP-3 α signals through the G protein-coupled receptor CCR6 to function as a chemoattractant to lymphocytes and dendritic cells.

Expand 4 Items
Loading...
Rat Recombinant IL-6 (from E. coli)

Rat Recombinant IL-6 (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains.

Expand 4 Items
Loading...

N,N-Dimethylformamide ≥99.9% (by GC), Supelco®

Supplier: MilliporeSigma

Flammable.

Expand 2 Items
Loading...
Human Recombinant Leptin (from E. coli)

Human Recombinant Leptin (from E. coli)

Supplier: Fujifilm Irvine Scientific

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

Expand 1 Items
Loading...
Human Recombinant EBI3 (from E. coli)

Human Recombinant EBI3 (from E. coli)

Supplier: Fujifilm Irvine Scientific

Epstein-Barr virus induced gene-3 (EBI3) is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). EBI3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infection. EBI3 forms heterodimers with p28 to form interleukin 27 (IL-27), and with p35 to form interleukin 35 (IL-35). Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.

Expand 5 Items
Loading...
Human Recombinant EBI3 (Animal free) (from E. coli)

Human Recombinant EBI3 (Animal free) (from E. coli)

Supplier: Fujifilm Irvine Scientific

Epstein-Barr virus induced gene-3 (EBI3) is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). EBI3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infection. EBI3 forms heterodimers with p28 to form interleukin 27 (IL-27), and with p35 to form interleukin 35 (IL-35). Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.

Expand 4 Items
Loading...
Human Recombinant IL-5 (from E. coli)

Human Recombinant IL-5 (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interleukin 5 (IL-5) is a hematopoietic growth factor that is expressed in type 2 T helper (Th2) cells, mast cells, and eosinophils. It acts through the IL-5 receptor (IL-5R), stimulates B cell growth, and mediates eosinophil activation. Human and mouse IL-5 show cross-reactivity.

Expand 2 Items
Loading...
Human Recombinant I-TAC (from E. coli)

Human Recombinant I-TAC (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interferon-inducible T cell alpha chemoattractant (I-TAC), or CXCL11, is expressed at high levels in leukocytes, pancreas, and liver cells. I-TAC gene expression is induced by interferons alpha (IFN-α), beta (IFN-β), and gamma (IFN-ɣ). I-TAC is the dominant ligand known to bind the chemokine receptor CXCR3, thus acting as a stronge agonist. I-TAC functions as a chemoattractant for interleukin 2 (IL-2)-activated T cells.

Expand 5 Items
Loading...

Human Recombinant CTGrade GMP rh IL-7 (from E. coli)

Supplier: Fujifilm Irvine Scientific

CTGrade GMP rh IL-7 is a recombinant human protein that is produced from E. coli and is designed to support basic, translational, and clinical research, as well as commercial applications.

Expand 3 Items
Loading...
Antifoam C Medical Emulsion, Biotech Reagent, J.T.Baker®

Antifoam C Medical Emulsion, Biotech Reagent, J.T.Baker®

Supplier: VWR International

Antifoam C Medical Emulsion, Biotech Reagent, J.T.Baker®

Expand 1 Items
Loading...

Human Recombinant rh GM-CSF (GMP) (from E. coli)

Supplier: Fujifilm Irvine Scientific

CTGrade GMP rh GM-CSF is a recombinant human protein that is produced from E. coli and is designed to support preclinical and clinical research, as well as commercial applications.

Expand 3 Items
Loading...
Mouse Recombinant IL-17AF  (from E. coli)

Mouse Recombinant IL-17AF (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling.

Expand 5 Items
Loading...
Human Recombinant IL-21 (Animal free) (from E. coli)

Human Recombinant IL-21 (Animal free) (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains. Human IL-6 is active on mouse and rat cells.

Expand 4 Items
Loading...
Mouse Recombinant IL-11 (from E. coli)

Mouse Recombinant IL-11 (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling.

Expand 4 Items
Loading...
Rat Recombinant FGF-basic (Animal free) (from E. coli)

Rat Recombinant FGF-basic (Animal free) (from E. coli)

Supplier: Fujifilm Irvine Scientific

Basic fibroblast growth factor (FGF-basic), also known as FGF-2, is expressed by endothelial cells and is a mediator of angiogenesis. FGF-basic also has cardioprotective functions during heart injury. FGF-basic binds heparin in order to signal through fibroblast growth factor (FGF) receptor tyrosine kinases. 

Expand 5 Items
Loading...
Mouse Recombinant SCF (from E. coli)

Mouse Recombinant SCF (from E. coli)

Supplier: Fujifilm Irvine Scientific

Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a critical role in the maintenance, survival, and differentiation of hematopoietic stem cells. While human SCF shows no activity on murine cells, murine and rat SCF are active on human cells.

Expand 4 Items
Loading...
Human Recombinant RANK LIGAND (from E. coli)

Human Recombinant RANK LIGAND (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interleukin-1 receptor antagonist (IL-1RA) binds the interleukin 1 receptor (IL-1R) to antagonize interleukin 1 alpha and beta signaling. IL-1RA is secreted by immune cells, epithelial cells, hepatocytes, and adipocytes to inhibit IL-1-induced inflammation. IL-1RA therapy is used to treat auto-inflammatory diseases such as diabetes and rheumatoid arthritis.

Expand 4 Items
Loading...
Human Recombinant MIP-3 B  (from E. coli)

Human Recombinant MIP-3 B (from E. coli)

Supplier: Fujifilm Irvine Scientific

Macrophage inflammatory protein-3 beta (MIP-3 β), also called CCL19, is a chemokine that is expressed in the thymus, lymph nodes, and activated bone marrow stromal cells. MIP-3 β signals through the G protein-coupled receptor CCR7 to regulate normal lymphocyte recirculation. MIP-3 β also functions during T cell trafficking to the thymus, and in T cell and B cell homing to the lymph nodes and secondary lymphoid organs. Human MIP-3 β shows activity on mouse cells.

Expand 5 Items
Loading...
Mouse Recombinant FOLLISTATIN (from E. coli)

Mouse Recombinant FOLLISTATIN (from E. coli)

Supplier: Fujifilm Irvine Scientific

Resistin-like molecule-alpha (RELM-α) is a member of the RELM family of secreted proteins containing conserved C-terminus cysteines. The RELM family consists of Resistin (FIZZ3), RELM-α (FIZZ1), RELM-β (FIZZ2), and RELM-γ (FIZZ4). RELM-α and Resistin are secreted by adipocytes, unlike RELM-β which is secreted by gastrointestinal epithelial cells, and RELM-γ which is expressed by peripheal blood granulocytes and bone marrow cells.

Expand 5 Items
Loading...
Mouse Recombinant IL-6 (from E. coli)

Mouse Recombinant IL-6 (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains. Human IL-6 is active on mouse and rat cells.

Expand 4 Items
Loading...
Mouse Recombinant IFN-G (from E. coli)

Mouse Recombinant IFN-G (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Mouse IFN-γ is not cross-reactive with human IFN-γ.

Expand 5 Items
Loading...

Human Recombinant PDGF-AA (from E. coli)

Supplier: Fujifilm Irvine Scientific

CTGrade GMP rh PDGF-AA is a recombinant human protein that is produced from E. coli and is designed to support preclinical and clinical research, as well as commercial applications. 50 µg, 100 µg, and 1 mg sizes are available.

Expand 3 Items
Loading...
Rat Recombinant IGF-I (from E. coli)

Rat Recombinant IGF-I (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway.  IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules.

Expand 5 Items
Loading...
Human Recombinant RANK LIGAND (Animal free) (from E. coli)

Human Recombinant RANK LIGAND (Animal free) (from E. coli)

Supplier: Fujifilm Irvine Scientific

Stromal cell-derived factor-1 alpha (SDF-1 α), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1α signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes. Human and mouse SDF-1 α share 99% sequence identity.

Expand 4 Items
Loading...
Mouse Recombinant EXODUS-2/CCL21 (from E. coli)

Mouse Recombinant EXODUS-2/CCL21 (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interferon gamma-induced protein 10 (IP-10), or CXCL10, is a chemokine secreted by monocytes, endothelial cells, and fibroblasts in response to interferon gamma (IFN-γ). IP-10 functions as a chemoattractant for activated T cells, monocytes, dendritic, and natural killer (NK) cells that express the G protein-coupled receptor CXCR3. IP-10 is an important factor in autoimmune diseases such as Hashimoto's thyroiditis, Graves' disease, and Type 1 diabetes mellitus.

Expand 5 Items
Loading...
Human Recombinant IL-11 (from E. coli)

Human Recombinant IL-11 (from E. coli)

Supplier: Fujifilm Irvine Scientific

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. Human IL-11 shows activity on murine cells.

Expand 4 Items
Loading...
Ward's® Basic Electrophoresis Bundles

Ward's® Basic Electrophoresis Bundles

Supplier: Avantor

These bundles are everything you need to perform agarose gel electrophoresis.

Expand 3 Items
Loading...
Sort By
Recommended for You