9693 Results for: "Proteintech"

Supplier: Proteintech

The GTF2H3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GTF2H3. This antibody recognizes human antigen. The GTF2H3 antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The RCOR3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human RCOR3. This antibody recognizes human, mouse, rat antigen. The RCOR3 antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The C2orf3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human C2orf3. This antibody recognizes human antigen. The C2orf3 antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The BHMT2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human BHMT2. This antibody recognizes human,mouse,rat antigen. The BHMT2 antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The CCL17 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CCL17. This antibody recognizes human antigen. The CCL17 antibody has been validated for the following applications: ELISA, IHC, WB analysis.

Supplier: Proteintech

The PLS3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PLS3. This antibody recognizes human,mouse,rat antigen. The PLS3 antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

MAGED1 (also known as NRAGE or Dlxin-1) is a member of the type II melanoma antigen (MAGE) family of protein. MAGED1 can interact with the nerve growth factor receptor p75NTR, antagonize the association of p75NTR with TrkA, inhibit cell cycle progression, and facilitate p75NTR-mediated apoptosis . It has been reported that MAGED1 binds Dlx5 and regulates its transcriptional function. In vivo, MAGED1 binds not only Dlx5 but also Dlx7 and Msx2 and forms homomultimers . MAGED1 knockout mice show depressive behavior and impairments of circadian rhythm . Three transcript variants encoding two different isoforms (86kDa and 92 kDa) have been found for the gene of MAGED1.

Supplier: Proteintech

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP is a widely expressed, secreted galectin. It has been found elevated in the serum of patients with various types of breast, lung, colorectal, ovary, and endometrial cancer, and in those infected by the human immunodeficiency virus (HIV). High expression levels of LGALS3BP are associated with a shorter survival, the occurrence of metastasis or a reduced response to chemotherapy. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Immunoblotting showed that LGALS3BP is likely contained in breast milk, serum, semen, saliva, urine, and tears.

Supplier: Proteintech

Anti-BETA ADDUCIN Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 1-331 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, Recommended Storage: - 20 C or lower

Supplier: Proteintech

UBQLN3(Ubiquilin-3) may interact with the testis-specific cyclin A1 and regulate cell cycle progression during spermatogenesis, as does frog Xdrp1, with which UBQLN3 shares sequence similarity.UBQLN3 expression is not observed in mouse eye, thyroid, pancreas,smooth muscle, ovary, submaxillary gland, uterus, and epididymis by northern blot.

Supplier: Proteintech

The Cytokeratin 18 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human Cytokeratin 18. This antibody recognizes human antigen. The Cytokeratin 18 antibody has been validated for the following applications: ELISA, WB, FC, IF, IHC analysis.

Supplier: Proteintech

Anti-HIKESHI(Polyclonal) Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 1-193 amino acid, Format:Antigen affinity purification, Application: ELISA, IHC, WB, Recommended Storage: - 20 C or lower

Supplier: Proteintech

Aldehyde dehydrogenases (ALDHs) belong to a superfamily of NAD(P)+-dependent enzymes, which catalyze the oxidation of endogenous and exogenous aldehydes to their corresponding acids. ALDH1B1 is a mitochondrial ALDH that it is dramatically upregulated in human colonic adenocarcinoma, making it a potential biomarker for human colon cancer.. ALDH1B1 is a homotetramer expressed in various adult and fetal human tissues including liver, testis, kidney, skeletal muscle, heart, placenta, brain and lung.

Supplier: Proteintech

ACTA2 (also known as α-smooth muscle actin or α-SMA) belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 is primarily expressed in vascular smooth muscle and anti-ACTA2 is commonly used to marker smooth muscle cells. This antibody is specific to the ACTA2. It selectively stains the vascular smooth muscle but not cardiac or skeletal muscle.

Supplier: Proteintech

HPSE(Heparanase) is also named as HEP, HPA, HPA1, HPR1, HPSE1, HSE1 and belongs to the glycosyl hydrolase 79 family. It is a endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. HPSE is essential in the disassembly of the extracellular matrix (ECM) by invading cells. It has 3 isoforms produced by alternative splicing with the molecular weight of 61 kDa, 55 kDa and 53 kDa. The full length protein has six glycosylation sites. The cleavage of the 65 kDa form leads to the generation of a linker peptide, and 8 kDa and 50 kDa products. The active form, the 8/50 kDa heterodimer, is resistant to degradation and glycosylation of the 50 kDa subunit appears to be essential for its solubility.

Supplier: Proteintech

REG1 (Cellular repressor of E1A-stimulated genes 1) shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. The monomers of CREG can associate into dimers and the dimerization is observed not only in the crystal but also in solution.The cellular repressor of E1A-stimulated genes (CREG) is a secreted glycoprotein that inhibits cell proliferation and/or enhances differentiation. CREG is widely expressed in adult tissues such as the brain, heart, lungs, liver, intestines and kidneys in mice.

Supplier: Proteintech

Anti-CPSF2 Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 433-782 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IHC, Recommended Storage: - 20 C or lower

Supplier: Proteintech

CPB2(Carboxypeptidase B2) belongs to the peptidase M14 family. The CPB2 gene encoding TAFI is a candidate gene for blood pressure. Circulating CPB2 and platelets may potentially contribute to regulating the bioactivity of leukocyte chemoattractant chemerin (RARRES2), and further extend the molecular link between blood coagulation/fibrinolysis and CMKLR1-mediated immune responses. This protein has 2 isoforms produced by alternative splicing.

Supplier: Proteintech

Cellular retinoic acid binding protein 2 (CRABP2, synonyms: RBP6, CRABP-II). A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. CRABP2 is important in retinoic acid-mediated regulation of human skin growth and differentiation. It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein.

Supplier: Proteintech

Nuclear pore complex protein Nup133 is a protein that in humans is encoded by the NUP133 gene. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. 

Supplier: Proteintech

Anti-NUDT9 Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 28-350 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IHC, Recommended Storage: - 20 C or lower

Supplier: Proteintech

Anti-NUP53 Antibody, Host Species: Rabbit, Cross Reactivity: Human, Mouse, Rat, Immunogen: Fusion Protein, 1-326 amino acid, Format:Antigen affinity purification, Application: ELISA, Recommended Storage: - 20 C or lower

Supplier: Proteintech

Anti-PCDHGB3 Antibody, Host Species: Rabbit, Cross Reactivity: Human, Immunogen: Fusion Protein, 30-270 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IF, Recommended Storage: - 20 C or lower

Supplier: Proteintech

PEX14 (peroxisomal biogenesis factor 14) is a peroxisomal membrane protein that is essential for protein docking onto the peroxisomes. It is a central component of the peroxisimal matrix protein import machinery and interacts with PEX5 and PEX19. PEX14 is ubiquitously expressed and defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK). This antibody can be used to detect endogenous PEX14 with an apparent molecular weight of 57 kDa and recognize peroxisomal structures in human, monkey and mouse cells.

Supplier: Proteintech

Oncostatin M (OSM) is a member of interleukin-6 family cytokines that modulates proliferation and differentiation in numerous cells . OSM signals via a receptor complex comprising gp130 and the OSMR (also refered to as OSMRβ) . OSMR is a single-pass membrane protein which belongs to the type I cytokine receptor family. OSMR mRNA is expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and a variety of tumor cell lines . It has also been shown that OSMR associates with IL31RA to form the heterodimeric IL31 receptor .

Supplier: Proteintech

Anti-PSG4 Antibody, Host Species: Rabbit, Cross Reactivity: Human, Immunogen: Recombinant Protein, C-term-300 amino acid, Format:Antigen affinity purification, Application: ELISA, IHC, WB, Recommended Storage: - 20 C or lower

Supplier: Proteintech

Anti-FSCN3 Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 142-498 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IHC, Recommended Storage: - 20 C or lower

Supplier: Proteintech

GATA4 is a transcriptional activator. GATA4 binds to the consensus sequence 5'-AGATAG-3'. GATA4 acts as a transcriptional activator of ANF in cooperation with NKX2-5. Mutation of GATA4 will cause the atrial septal defect type 2 (ASD2). The antibody is specific to GATA4.

Supplier: Proteintech

Fibronectin 1 (FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellular matrix (cellular FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.

Supplier: Proteintech

The selective RNA-binding protein FMRP forms a messenger ribonucleoprotein complex that associates with polyribosomes, implicating in regulation of translation. FMR1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to and reperss the mRNA. It also has a role in the transport of mRNA from the nucleus to the cytoplasm.