68333 Results for: "L-Pyroglutamic acid pentachlorobiphenyl ester"

Supplier: Bachem Americas

Sequence: Pyr-OPcp

Supplier: Prosci

Pyroglutamic acid truncated amyloid beta 11-40/42 may have a greater propensity to aggregate under physiological conditions. In addition, this pyrE modification has been implicated as the molecular species responsible for seeding larger oligomers of amyloid-beta. Pyroglutamic acid truncated amyloid beta 11-40/42’s exact involvement in the pathophysiology of Alzheimer’s disease has not been established

Supplier: Prosci

QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. It also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. QPCT may be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: Bachem Americas

Sequence: Z-Pyr-OH

Supplier: TCI America

CAS Number: 53100-44-0
MDL Number: MFCD00672316
Molecular Formula: C10H15NO5
Molecular Weight: 229.23
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 119
Specific rotation [a]20/D: -34 deg (C=1, CHCl3)
Storage Temperature: 0-10°C

Supplier: Bachem Americas

Sequence: Boc-Pyr-OH

Supplier: TCI America

CAS Number: 149-87-1
MDL Number: MFCD00064322
Molecular Formula: C5H7NO3
Molecular Weight: 129.12
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Melting point (°C): 184

Supplier: TCI America

CAS Number: 98-79-3
MDL Number: MFCD00005272
Molecular Formula: C5H7NO3
Molecular Weight: 129.12
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Melting point (°C): 160
Specific rotation [a]20/D: -10 deg (C=5, H2O)

Supplier: Bachem Americas

Sequence: Pyr-OH

Supplier: Bachem Americas

Sequence: Pyr-AMC

Supplier: Thermo Scientific Chemicals

Fieser: 1,977

Supplier: Thermo Scientific

GGCT (EC 2. 3. 2. 4) catalyzes the formation of 5-oxoproline (pyroglutamic acid) from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis.

Supplier: Thermo Scientific Chemicals

(±)-2-Pyrrolidinone-5-carboxylic acid 99%

Supplier: Restek

Standard 2,3',4,4',5-Pentachlorobiphenyl, CAS Number:31508-00-6, Concentration in Solvent: 10 ug/mL in isooctane, Min Shelf Life: 6 months, Volume: 1 mL/ampul

Supplier: Restek

Contains eight components, those are 2-chlorobiphenyl, 2,3-dichlorobiphenyl, 2,4,5-trichlorobiphenyl, 2,2',4,4'-tetrachlorobiphenyl, 2,2',3',4,6-pentachlorobiphenyl, 2,2',4,4',5,6'-hexachlorobiphenyl, 2,2',3,3',4,4',6-heptachlorobiphenyl and 2,2',3,3',4,5',6,6'-octachlorobiphenyl.

Supplier: Restek

Contains 19 components, those are 2-chlorobiphenyl , 2,3-dichlorobiphenyl , 2,2',5-trichlorobiphenyl , 2,4',5-trichlorobiphenyl, 2,2',3,5'-tetrachlorobiphenyl, 2,2',5,5'-tetrachlorobiphenyl, 2,3',4,4'-tetrachlorobiphenyl, 2,2',3,4,5'-pentachlorobiphenyl, 2,2',4,5,5'-pentachlorobiphenyl, 2,3,3',4',6-pentachlorobiphenyl, 2,2',3,4,4',5'-hexachlorobiphenyl, 2,2',3,4,5,5'-hexachlorobiphenyl, 2,2',3,5,5',6-hexachlorobiphenyl, 2,2',4,4',5,5'-hexachlorobiphenyl, 2,2',3,3',4,4',5-heptachlorobiphenyl, 2,2',3,4,4',5,5'-heptachlorobiphenyl, 2,2',3,4,4',5',6-heptachlorobiphenyl, 2,2',3,4',5,5',6-heptachlorobiphenyl and 2,2',3,3',4,4',5,5',6-nonachlorobiphenyl.

Supplier: Restek

Contains: 2,4,4'-trichlorobiphenyl (BZ #28), 2,2',5,5'-tetrachlorobiphenyl (BZ #52), 2,2',4,5,5'-pentachlorobiphenyl (BZ #101), 2,3',4,4',5-pentachlorobiphenyl (BZ #118), 2,2',3,4,4',5'-hexachlorobiphenyl (BZ #138), 2,2',4,4',5,5'-hexachlorobiphenyl (BZ #153), 2,2',3,4,4',5,5'-heptachlorobiphenyl (BZ #180).

Supplier: Bachem Americas

The pyroglutamate-modified amyloid-β peptides derived from Aβ40 (H-7422) and Aβ42 (H-4796) have gained considerable attention as potential key participants in the pathology of Alzheimer's disease (AD) due to their abundance in AD brain, high aggregation propensity, stability, and cellular toxicity. Aβ40 and 42 can be N-terminally truncated by action of cathepsin B. The cyclization of Glu³ is catalyzed by glutaminyl cyclase. Hence, inhibition of these enzymes could be a therapeutic approach to AD.

Supplier: Bachem Americas

pEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV, the N-terminally truncated isoform of the amyloid β-protein (Aβ) beginning with a pyroglutamate (Pyr) residue at position 11 was used in experiments studying the generality of fibrillogenesis-related helix formation. Comparing the fibrillogenesis kinetics of many of the most important clinically relevant amyloid β-protein alloforms it could be observed that among these peptides (Pyr¹¹)-amyloid β-protein (11-40) exhibited the greatest retardation of fibrillization rate.

Supplier: HARDY DIAGNOSTICS CA

For use in conjunction with PYR testing for the detection of pyroglutamate aminopeptidase found in group A streptococci Streptococcus pyogenes) and group D enterococci

Supplier: VWR International

Meets ACS Specifications for General Use

Supplier: VWR International

Supplier: Avantor

Synthesize a Variety of Esters by Reactions of Organic Acids and Alcohols

Supplier: Ward's Science

Identify the Chemical by its SMELL!

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Ethyl Acetate, AR® (ACS)

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Methylparaben, NF - GenAR®

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Amyl acetate. CAS RN 628-63-7. Formula Weight: 130.19. Density: 0.88 kg/L. Mixed isomers, purified grade. Subject to postal/shipping restrictions. 50mL.

Supplier: Ward's Science

CAS Number: 8001-31-8
Formula: Glycerin ester of C₆-C₁₆ fatty acids
Density (g/mL): 0.922-0.926
Boiling Point (°C): >232
Freezing Point (°C): 21-25
Solubility: Many Organic Solvents, Not Miscible with Water
Synonyms: Copra Oil
Shelf Life (months): 36
Storage: Green

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

White powder.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

For high performance liquid chromatography. Packaged under nitrogen. UV cutoff 255nm. Lot analysis on label.