1119 Results for: "Genscript"

Supplier: Genscript

THE™ GST antibody [Biotin], mAb, Mouse recognizes C-terminal, N-terminal and internal tagged GST fusion proteins.

Supplier: Genscript

THE™ V5 Tag antibody [HRP], mAb, Mouse recognizes C-terminal tagged fusion proteins and it slightly recognizes N-terminal V5 tagged fusion proteins.

Supplier: Genscript

The product is specific for Cetuximab. This antibody blocks Cetuximab binding with EGFR (Z03202, EGFR, His, Human) in ELISA. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01939-40, Anti-Cetuximab Antibody (20H1), mAb, Mouse.

Supplier: Genscript

The product is specific for Rituximab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01970-40, Anti-Rituximab Antibody (17B6), mAb, Mouse.

Supplier: Genscript

MonoRab™ HA tag antibody recognizes HA tags placed at N-terminal, C-terminal, and internal regions of fusion proteins.

Supplier: Genscript

GenScript rabbit anti-V5-tag polyclonal antibody specifically recognizes V5 tagged fusion proteins.

Supplier: Genscript

GenScript MonoRab™ Rabbit Anti-Camelid VHH Cocktail [HRP] is specific for Camelid sdAb (Llama and Camel). It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.

Supplier: Genscript

The product is specific for durvalumab.

Supplier: Genscript

The product is specific for Obinutuzumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01947-40, Anti-Obinutuzumab Antibody (16B7) [Biotin], mAb, Mouse.

Supplier: Genscript

GenScript MonoRab™ Rabbit Anti-Camelid VHH Cocktail [Biotin] is specific for Camelid VHH antibody (Llama, Alpaca and Camel). It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.

Supplier: Genscript

The product is specific for human TIGIT.

Supplier: Genscript

GenScript MonoRab Rabbit Anti-Camelid VHH Antibody [Biotin], mAb is specific for Camelid VHH Antibody (Alpaca, Llama and Camel). The monoclonal antibody has no cross-reactivity with mouse, rat, rabbit, chicken, goat or human immunoglobulins.

Supplier: Genscript

THE™ NWSHPQFEK Tag antibody, mAb, Mouse recognizes NWSHPQFEK tags localized at the N-terminal and C-terminal region of Strep II-tagged fusion proteins.

Supplier: Genscript

The product is specific for Pembrolizumab.

Supplier: Genscript

THE™ NWSHPQFEK Tag antibody [Biotin], mAb, Mouse recognizes N-terminal and C-terminal Strep II tagged fusion proteins.

Supplier: Genscript

The product is specific for SARS-CoV-2 Nucleocapsid protein.

Supplier: Genscript

The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A02008-40, MonoRab™ anti-pembrolizumab antibody (94B9), mAb, rabbit.

Supplier: Genscript

CD3 is a member of the immunoglobulin superfamily, expressed on T cells. It is composed of four distinct chains (ε, γ, δ, ζ). CD3 antigen can form a complex with the T cell receptor (TCR) to generate an activation signal in T cells, which plays an important role in TCR signal transduction and both cytotoxic T cell ( CD8 + naïve T cells) and T helper cells (CD4+ naive T cells) activation.

Supplier: Genscript

This antibody recognizes c-Myc tagged fusion proteins.

Supplier: Genscript

The product is specific for Rituximab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01942-40, MonoRab™ Anti-Rituximab Antibody (137C6), mAb, Rabbit.

Supplier: Genscript

GenScript's Bis-Tris gels are high-performing polyacrylamide gels designed to separate a wide range of protein sizes by electrophoresis. The gels are cast in a neutral pH buffer that minimizes polyacrylamide hydrolysis and increases gel stability. Furthermore, the neutral pH which minimizes protein modification when compared to Tris-glycine gels.

Supplier: Genscript

Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5, or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions. Anti-Eculizumab Antibody (4F6), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Eculizumab.

Supplier: Genscript

Rabbit IgG control is suitable for use as control, standard, blocking agent, or coating protein in a variety of assays, including ELISA, western blot, immunoprecipitation, immunodiffusion, and immunoelectrophoresis, flow cytometry and immunofluorescence. GenScript MonoRab™ rabbit IgG control [PE] (whole molecule), mAb is PE conjugated MonoRab™ rabbit IgG control (whole molecule), mAb.

Supplier: Genscript

Etanercept with trade name Enbrel, is an FDA-approved drug to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis. Etanercept is a fusion protein made from the combination of two naturally occurring soluble human 75-kilodalton TNF receptors linked to an Fc portion of an IgG1. Etanercept treats autoimmune diseases by interfering with tumor necrosis factor-alpha (TNF alpha, a soluble inflammatory cytokine) by acting as a TNFalpha inhibitor.Anti-Etanercept Antibody (4H5), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Etanercept.

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Genscript

Adeno-associated virus type 2 (AAV2) is a valuable vector for gene therapy. It is one member of the human parvovirus family which depends on co-infection with helper viruses such as adenovirus or herpes virus for efficient reproduction. The AAV2 capsid (intact particle) comprises three types of subunits, VP1, VP2, and VP3, a total of 60 copies in a ratio of 1:1:8 (VP1:VP2:VP3). For the application of AAV2 vector in gene therapy, the determination of total capsid titer is essential, accurate characterization and quantification of purified AAV2 particle product represent a critical step for clinical application. GenScript Anti-AAV2 (intact particle) Antibody (2C4), mAb, Mouse is produced from cell culture in vitro under conditions free from animal-derived components.

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Genscript

Ustekinumab with trade name Stelara, is an FDA-approved drug to Crohn's disease, Ulcerative Colitis, Plaque Psoriasis and Psoriatic Arthritis, targeting both interleukins (IL)-12 and IL-23. Ustekinumab is a fully human immunoglobulin G1 kappa mAb that binds to IL-12 and IL-23. Ustekinumab binds to the p40 subunit common to IL-12 and IL-23 and prevents their interaction with the IL-12 receptor β1 subunit of the IL-12 and IL-23 receptor complexes, thereby disrupting the proinflammatory pathway. GenScript Anti-Ustekinumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Ustekinumab.

Supplier: Genscript

CD4 (cluster of differentiation 4) is a single glycoprotein with a molecular weight of 59 kDa. CD4 antigen is expressed on the surface of T helper cells, monocytes and macrophages. CD4 recognizes antigens associated with MHC class II molecules, and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4+ T helper cells bind and activate B cells to create immunoglobulins.

Supplier: Genscript

SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). Nucleocapsid Protein is a most abundant structure protein of the coronavirus which is associated with nucleic acid.