9604 Results for: "4-(1,1-dioxidothiomorpholino)benzaldehyde"

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Mettler Toledo

METTLER TOLEDO ME-TE balances are reliable balances for every lab that combine essential weighing functions with ease of use to deliver accurate results day after day.

Supplier: Eppendorf

The eppendorf vacufuge plus facilitates fast and efficient, gentle vacuum concentration of DNA, RNA, nucleotides, proteins and other liquid or wet samples with its advanced heating technology. Its coated lid provides superior chemical resistance against many acids and organic solvents.

Supplier: Prosci

Fat Free Antibody: Fat Free, also known as ANG2, was identified though a yeast two-hybrid screen using VP53. It is thought to be a structural and functional homolog of the yeast protein VPS51, a protein that together with VPS52, VPS53, and VPS54 form the Golgi-associated retrograde protein (GARP) complex that mediates the tethering and fusion of endosome-derived transport carriers to the trans-Golgi network (TGN). Similar to depletion of any of the VPS52, VPS53, or VPS54, depletion of Fat Free using RNAi impairs protein retrieval to the TGN indicating that Fat Free is missing component of the GARP complex in most eukaryotes.

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Proteintech

Rab11a, Rab11b and Rab25 comprise a subfamily of Rab proteins that belong to the Ras-related small GTPase protein superfamily . Rab11 proteins are involved in endocytosis and plasma membrane recycling in non-polarized and polarized cells ( PMID: 8638719, PMID: 8922376). Rab11a and Rab11b are ubiquitously expressed in most tissues, while Rab25 is only expressed in epithelial cells. Rab11a is known to regulate the recycling of internalized cell surface proteins and receptors from the early endosome through the trans-Golgi network . The antibody is specific to RAB11A, and has no cross reaction to RAB11B.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

J.T.Baker® Cell Lysis Solution Biotech Reagent is a cGMP pre-formulated and ready to use detergent optimized for the extraction and recovery of AAV particles from producer cell lines (HEK293 parental and suspension lines, SF9). J.T.Baker® Cell Lysis Solution is a proprietary blend of nonionic surfactants, free of octyl phenol ethoxylate, which demonstrates comparable performance industry standard detergents while addressing environmental concerns associated with REACH and downstream clearance concerns. Designed for Gene Therapy workflows, this formulation is easy to use and handle as it is ready-to-use, has low viscosity, does not require cold temperature shipping or storage, and is available in sizes to support processes from development to large scale commercial batches. Detail description provided in technical literature.

Supplier: Contec

PROSAT® Sterile Polypropylene wipes are presaturated with 70% denatured ethanol and 30% deionized water. The meltblown polypropylene wipes provide a consistent release of solvent to thoroughly remove surface contaminants in critical environments. These wipes are exceptionally clean and also free from additives of any kind. This particular meltblown polypropylene contains very low levels of sodium and other ions.

Supplier: Bel-Art Products, a Part of SP

Lab-Aire® II Electric Drying Racks accelerate drying of labware with warm, circulating air while their compact footprint uses minimal benchtop space.

Supplier: G-Biosciences

G-Biosciences' Streptavidin Resin is designed for the single step small and large scale affinity purification of proteins and antibodies with a biotin tag

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Prosci

FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin.FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).

Supplier: Genetex

Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM]

Supplier: Justrite

This Double Cylinder Hand Truck with Firewall provides safety when moving and storing of gas cylinders.

Supplier: Sartorius

The arium® mini Essential Ultrapure Water benchtop system is designed for direct connection to a pre-treated water supply.

Supplier: Prosci

ZIP11 Antibody: ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist.

Supplier: Prosci

Homeobox proteins are transcription factors notable for their ability to regulate embryogenesis. The reproductive homeobox proteins (Rhox) are expressed in a cell type-specific manner; several are hormonally regulated, and their expression pattern during postnatal testis development corresponds to their chromosomal position. Most of the Rhox proteins are expressed in Sertoli cells, the nurse cells in direct contact with developing male germ cells, suggesting that they regulate the expression of somatic-cell gene products critical for germ cell development.

Supplier: Thermo Scientific

This antibody is predicted to react with bovine, canine and mouse based on sequence homology. The protein encoded by this gene belongs to the membrane-associated guanylate kinase family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain . This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Supplier: ONSET COMPUTER CORPORATION

InTemp CX402-Txxx (with glycol bottle) data loggers monitor temperatures in refrigerators, freezers and other temperature-controlled environments to comply with global GDP requirements.

Supplier: Eco Lab

The Bioquell L-4 is a mobile Hydrogen Peroxide Vapor bio-decontamination generator that can be connected to enclosures, equipment, isolators and more in your facility or, with additional accessories, be used for room/zone bio-decontamination.

Supplier: Prosci

CARMA1 Antibody: CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. Both CARMA1 and CARMA3 associate with NEMO, the regulatory subunit of the Ikappa K complex, thereby regulating activation of the NF-kappa B transcription factor. Also, gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS, indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems.

Supplier: Genscript

GenScript MonoRab™ Rabbit Anti-Camelid VHH Antibody [HRP], mAb is specific for Camelid sdAb (Alpaca, Llama and Camel). The monoclonal antibody has no cross-reactivity with mouse, rat, rabbit, chicken, goat or human immunoglobulins.

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx) is a peptide chain about 110 amino acids long comprising one variable domain of a heavy-chain antibody (VHH fragment). Like a whole antibody, a single-domain antibody is able to bind selectively to a specific antigen. Such antibodies allow a broad range of applications in biotechnical as well as therapeutic fields due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and cause anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: VWR International

VWR® Series –80 °C ultra-low temperature (ULT) freezers, powered by the H-Drive refrigeration system, are designed for efficiency. The units enable the same excellent experience as upright ULT freezers, with an additional benefit of enhanced performance. As a result, the series delivers a foundational ULT experience with the reliability and performance needed to protect your work—and the sustainability to meet global compliance.

Supplier: ONSET COMPUTER CORPORATION

InTemp CX402-xxM (with probe only) data loggers monitor temperatures in refrigerators, freezers, and other temperature-controlled environments to comply with global GDP requirements.

Supplier: PERKINELMER SCIENTIFIC CANADA ULC

A single software platform incorporates all of the functions required for infrared analyses, complete with instrument control, data manipulation and analysis, and flexible report utilities.

Supplier: SLICE, INC.

This sleek, portable tool brings safety to the Everyday Carry community. It features the Slice® patent-pending grinding process, which creates a finger-friendly® edge that is safe to the touch and effective at cutting a wide variety of materials. The handle has a textured surface for a comfortable grip.

Supplier: Prosci

RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T-cell proliferation in a mixed lymphocyte reaction, to promote the survival of RANK + T cells, and to regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG. Binding of soluble OPG to sRANKL inhibits osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, thereby leading to excess accumulation of bone and cartilage. Recombinant rat sRANKL is a 19.4 kDa polypeptide comprising the TNF homologous region of RANKL (174 amino acid residues).

Supplier: Genscript

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Supplier: Eppendorf

For any application that requires sample/reaction mixing and heating the Eppendorf® ThermoMixer F family is what you need. Whether you work with 0.5/1.5/2.0 ml tubes or plates (MTP and DWP) the dedicated fixed blocks offer a perfect solution for your special application.