28362 Results for: "4,7,10-trioxatetracyclo[5.2.1.0(2,6).0(810)]undecan-3-one"

Supplier: Labconco

Enclosures provide a controlled environment in which to perform polymerase chain reaction (PCR) procedures

Supplier: Prosci

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.

Supplier: Labconco

These enclosures provide practical, economical protection of operator and environment for applications involving biohazardous material and toxic particulates

Supplier: Analytik Jena CA

The UVP GelStudio touch and non-touch are gel documentation systems which use a 12 MP camera for high sensitivity imaging for DNA gels, protein gels, Coomassie Blue, GelGreen, SYBR Green and a wide range of genomic applications.

Supplier: Prosci

Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Human IL10 is a non glycosylated polypeptide consisting of 178 amino acids. There is 73% homology between the human and mouse IL10 proteins, however, the human IL10 acts on both human and mouse target cells, while the mouse IL10 has species specific activity. The cellular sources of IL10 are CD4+ T cells and T cell clones, thymocytes, B cells and B cell lymphomas, macrophages, mast cell lines and keratinocytes. IL10 will stimulate the growth of stem cells, mast cells and thymocytes. IL10 enhances cytotoxic T cell development, and costimulates B cell differentiation and immunoglobulin secretion. IL10 inhibits cytokine production by macrophages and suppresses macrophage class II MHC expression. The human IL10 gene is on human chromosome

Supplier: Zymo Research

RNA from any sample (cells, tissues, biological fluids and more).

Supplier: Omega Bio-Tek

Magnetic separation device-A consists of 24 powerful magnetic rods that fit between the wells of commercially-available 96-well microplates

Supplier: G-Biosciences

G-Biosciences' OmniTemplate™ is specifically designed for the rapid isolation of a DNA template for polymerase chain reaction (PCR) analysis from mammalian tissue samples, blood and cell cultures

Supplier: Labconco

These enclosures provide practical, economical protection of operator and environment for applications that generate fine dusts or aerosols but do not provide product protection

Supplier: Corning

The AxyPrep Mag Plant genomic DNA kit is a magnetic beads based purification system that allows rapid and reliable isolation of high quality gDNA from multiple plant samples

Supplier: Beckman Coulter

If you need an approachable instrument for sorting multiple populations to generate high quality material for downstream assays, the CytoFLEX SRT benchtop cell sorter is quick to learn and easy to operate. This extension of the CytoFLEX platform is built on the same optical features as the flow cytometer, but equally important, it continues to adhere to the principles that made multicolor applications accessible to many biomedical research, core research, pharma and biotechs.

Supplier: Eco Lab

The Bioquell Qube is a configurable isolator integrated with Bioquell’s Hydrogen Peroxide Vapor technology. From its unique design to customizable features, the Bioquell Qube helps ensure your aseptic workspace needs are met for a productive working environment.

Supplier: Celestron International

StarSense Explorer is ideal for beginners thanks to the app’s user-friendly interface and detailed tutorials.

Supplier: Labconco

Portable exhausters for use with XPert™ balance enclosures and weigh boxes, Precise™ HEPA-filtered glove boxes, and Protector™ XVS ventilation stations, demonstration hoods, and workstations. Exhausters use carbon and/or HEPA filters to remove hazardous powders, particulates, or vapors from the exhaust air stream, returning filtered air to the environment. No ducting to the outside is required.

Supplier: Omega Bio-Tek

Isolate plasmid DNA from up to 5 ml culture in 9 minutes utilizing an innovative lysate clearance column.

Supplier: Orflo

Moxi GO II™ combines two instruments to deliver amazingly affordable, easy to use, maintenance-free, gold standard cell count accuracy and precision through the Coulter Principle and integrating 2 channels of flow cytometry. This unique combination covers a large number of routine cell assays (cell count, cell volume, viability, cell proliferation, transfection checks, apoptosis, phenotyping, cellular response) with quantitative single cell data output.

Supplier: Prosci

IFN gamma receptor beta is part of the receptor for interferon gamma. This class II cytokine receptor pairs with CDw119 to form the IFN gamma receptor and is an integral part of the IFN gamma signal transduction pathway. CDw119 serves as the IFN gamma binding chain and associates with the IFN gamma beta chain which is required for receptor signaling. The extracellular portion of both the IFN gamma receptor alpha and beta chains must be species matched. The IFN gamma receptor beta chain is expressed on T and B cells, NK cells, monocytes/ macrophages, and fibroblasts. Binding of IFN gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. It is also likely to interact with GAF. IFN gamma initiates and regulates a variety of immune responses and is required for signal transduction. Contains 2 fibronectin type III domains. Defects in IFN gamma Receptor beta are a cause of mendelian susceptibility to mycobacterial disease (MSMD), a rare condition that confers predisposition to illness caused by several mycobacteria strains

Supplier: Labconco

FreeZone® Triad® Benchtop Freeze Dryers are designed for multiple types of lyophilization: flask, bulk and stoppering vials. With the ability to freeze dry samples in so many different forms, the Triad’s versatility and compact design make it perfect for busy labs. Now with Lyo-Works™ OS the Triad is smarter than ever, making freeze drying even challenging samples easy.

Supplier: Zymo Research

Zymo-Seq™ ATAC library kit provides a simple and streamlined workflow for assay for transposase accessible chromatin with high throughput sequencing (ATAC-Seq) library preparation from mammalian cell and tissue input.

Supplier: New England Biolabs (NEB)

The NEBNext Poly(A) mRNA Magnetic Isolation Module is designed to isolate intact poly(A)+ RNA from previously isolated total RNA.

Supplier: Omega Bio-Tek

Isolate DNA from soil and water samples using magnetic beads.

Supplier: G-Biosciences

G-Biosciences' Rapid DNA Template Prep™ kit is suitable for the preparation of DNA templates from blood, cells, animal tissues and plant samples.

Supplier: Labconco

These low-profile enclosures provide user protection by keeping powders, particulates, and fumes contained during weighing procedures

Supplier: Prosci

Interleukins (ILs) are a large group of cytokines that are produced mainly by leukocytes, although some are produced by certain phagocytes and auxiliary cells. ILs have a variety of functions, but most function to direct other immune cells to divide and differentiate. Each IL acts on a specific, limited group of cells through a receptor specific for that IL. Human IL10 is a non glycosylated polypeptide consisting of 178 amino acids. There is 73% homology between the human and mouse IL10 proteins, however, the human IL10 acts on both human and mouse target cells, while the mouse IL10 has species specific activity. The cellular sources of IL10 are CD4+ T cells and T cell clones, thymocytes, B cells and B cell lymphomas, macrophages, mast cell lines and keratinocytes. IL10 will stimulate the growth of stem cells, mast cells and thymocytes. IL10 enhances cytotoxic T cell development, and costimulates B cell differentiation and immunoglobulin secretion. IL10 inhibits cytokine production by macrophages and suppresses macrophage class II MHC expression. The human IL10 gene is on human chromosome 1.

Supplier: Prosci

IFN gamma receptor beta is part of the receptor for interferon gamma. This class II cytokine receptor pairs with CDw119 to form the IFN gamma receptor and is an integral part of the IFN gamma signal transduction pathway. CDw119 serves as the IFN gamma binding chain and associates with the IFN gamma beta chain which is required for receptor signaling. The extracellular portion of both the IFN gamma receptor alpha and beta chains must be species matched. The IFN gamma receptor beta chain is expressed on T and B cells, NK cells, monocytes/ macrophages, and fibroblasts. Binding of IFN gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. It is also likely to interact with GAF. IFN gamma initiates and regulates a variety of immune responses and is required for signal transduction. Contains 2 fibronectin type III domains. Defects in IFN gamma Receptor beta are a cause of mendelian susceptibility to mycobacterial disease (MSMD), a rare condition that confers predisposition to illness caused by several mycobacteria strains

Supplier: Cytiva

Sephadex™ G-100 DNA Grade is ideal for use in preparing spin columns for DNA purification.

Supplier: New England Biolabs (NEB)

The New England Biolabs Magnetic mRNA Isolation Kit is designed to isolate intact poly(A)+ RNA from cells and tissue without requiring phenol or other organic solvents.

Supplier: Zymo Research

The OneStep™ PCR Inhibitor Removal Kit allows for the efficient removal of contaminants that can inhibit downstream enzymatic reactions from DNA and RNA preparations.

Supplier: Cytiva

Sera-Xtracta Cell-Free DNA Kit for the efficient extraction and purification of cell-free DNA (cfDNA) from plasma.

Supplier: Thermo Scientific

Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits. Store at 2 - 8˚C.