28362 Results for: "4,7,10-trioxatetracyclo[5.2.1.0(2,6).0(810)]undecan-3-one"

Supplier: Prosci

This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TECK displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. TECK binds to chemokine receptor CCR9. Two alternatively spliced variants encoding two different isoforms have been identified.

Supplier: Bel-Art Products, a Part of SP

Made from optical quality polycarbonate plastic material, these plain form hydrometers are durable and shatterproof making them ideal in situations where rough handling or contamination could be an issue, such as in the food or beverage industries.

Supplier: Therapak, LLC

The Therapak® range of insulated shippers features five popular cooler sizes that are inventoried at two locations in the United States in order to provide a maximum three day ground or truck shipment turnaround to any point in the Continental U.S. The two facility approach offers freight economies to Eastern, Central, and Western region shipping points. Warehouses are located in Buford, Georgia and Claremont, California.

Supplier: United Product & Instrument

Wards® Visible Spectrophotometers are perfect for your classroom or laboratory. The easy-to-use 1208 and 1204 are ideal for any standard application, while staying within a conservative budget. They have a high quality silicon photodiode detector and 1200 lines/mm diffraction grating that assures high performance, as well as a large digital display and built-in, automatic filters for easy operation. These spectrophotometers feature Absorbance, Transmittance, Factor and Concentration modes, as well as automatic zeroing and blanking with the touch of a single button. The 1208 and 1204 visible spectrophotometers feature both USB and RS-232C ports for data transfer and you can select optional Windows® based software for easy data collection and application expansion to standard curve and kinetics, Abs. and %T. Data can be easily exported to Microsoft Excel® for further processing, analysis and storage. Software can be used with Windows® 2000, ME, and XP. Bulb changes are quick and easy when needed and require no tools, or alignment. The large sample compartment can accept cuvettes up to 50 mm path length and can accept a variety of optional accessories.

Supplier: Rockland Immunochemical

Humanized Recombinant Anti-VEGFA ScFV fragment Antibody has been tested for use in Flow Cytometry, Western Blot, and ELISA. This antibody recognizes structured VEGF-A and will work in western blot when the protein has not been denatured with DTT or bMe. Although not tested, this antibody could be useful in in IHC and in in-vivo and other cellular assays. Specific conditions for reactivity should be optimized by the end user

Supplier: Prosci

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity.

Supplier: Prosci

IL-9 is a cytokine preferentially produced by T helper type 2 lymphocytes and active on various cell types such as T and B lymphocytes, mast cells and haemopoietic progenitors; but no effect of this cytokine has been reported so far on mononuclear phagocytes. IL-9 stimulates cell proliferation and prevents apoptosis. The IL-9 receptor (IL 9R) belongs to the haemopoietic receptor superfamily and its signal transduction involves mainly the (JAK/STAT) pathway. Some studies have implicated IL-9 as an important cytokine in a number of Th2 cytokine mediated pathologies, in particular asthma

Supplier: Prosci

Interleukin 6 (IL-6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL-6 has also been implicated in regulating adipose mass.

Supplier: Prosci

PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type palsminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder.

Supplier: VWR International

VWR® Advanced Mini Dry Block Heaters and Mini Dry Block Heaters with Heated Lid are ideal for a variety of applications that require accurate and repeatable results such as LAMP assays, immunoassays, enzyme reactions, and denaturations.

Supplier: Mettler Toledo

METTLER TOLEDO® MS-TS series balances are reliable and robust balances designed for everyday weighing.

Supplier: Labconco

Provides a non-ventilated, circulation-free work area designed to reduce cross-contamination during polymerase chain reaction (PCR) experiments. The unit is constructed of UV-resistant, glacier white, dry powder epoxy-coated aluminum and steel with 0.6cm (¹/₄") tempered safety glass sash and sides. Angled, hinged sash features a 19.8cm (7¹³/₁₆") high opening for closer, more comfortable viewing than vertical sashes, and an interlocked UV protection panel that must be in place to turn on UV light but can be removed when the light is off for full access to enclosure opening.

Supplier: Prosci

ADAM10 Antibody: Proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha ) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-alpha , notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-alpha , notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.

Supplier: Cytiva

The Amersham™ QuickStain Kit contains a Cy™5 fluorophore and labeling buffer for easy detection of proteins in SDSPAGE gels and on Western blotting membranes. The ready to use Cy5 N-hydroxysuccinimide (NHS) ester and Tris labeling buffer ensure robust and consistent labeling for detection of proteins in diverse samples.

Supplier: G-Biosciences

G-Biosciences' FOCUS™ Protein Alkylation Kit contains an ultra pure, proteomic grade iodoacetamide reagent for blocking thiols by alkylation in order to prevent the reoxidation of proteins

Supplier: Cytiva

903 sample collection card with four sample spots.

Supplier: Prosci

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by beta-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct subunits GluR1-4 and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR1 subunit is widely expressed throughout the nervous system. GluR1 is also potentiated by phosphorylation at Ser831. In addition, phosphorylation of this site has been linked to synaptic plasticity as well and learning and memory.

Supplier: Prosci

TNFRII (TNF Receptor II) is a member of the TNFR family of transmembrane proteins, and is expressed in immune cells and certain endothelial cells. It is a high affinity receptor for TNF alpha but manifests a lower affinity to TNF beta. Signaling through this receptor regulates various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNFRII consists of a 240 amino acid residue extracellular ligand binding portion, a 27 amino acid residue transmembrane segment and a 173 amino acid residue cytoplasmic domain.

Supplier: Thermo Fisher Scientific

Get premium performance and ultimate flexibility with the Orion™ Versa Star Pro™ Benchtop Multiparameter Meter with pH/ISE Module for pH, ion concentration, and temperature.

Supplier: Heidolph NA, LLC

Pump drives are suitable for use with applications requiring the highest standards involving corrosive solvents or sterilized media

Supplier: Thermo Fisher Scientific

The MaxQ™ 6000 orbital shakers have been designed for plasmid purification, protein expression, genetic research, solubility studies, bacteria and yeast growth, metabolism studies, and hybridization applications

Supplier: Thermo Fisher Scientific

The Barnstead GenPure xCAD Plus water purification systems provides up to 200L/day of Type 1, ultrapure (18.2 megohm) water from pre-treated feed water

Supplier: Eppendorf

Shake more. Shake faster. The temperature-controlled (refrigerated or non-refrigerated) Eppendorf Innova S44i shaker can fit up to twice as many flasks as other shakers and is ready to reliably support high-yield expression protocols at high speeds. The Eppendorf X-Drive maintains smooth shaking for more reproducible results.

Supplier: Nidec Shimpo America

FG-3000 Series Data logging, Compact Digital Force Gauge, Loaded with functionality to simplify compression and tension testing needs. Menu programming for easy selection and set-up of the instrument to desired requirements with three unique modes of operation.

Supplier: Quantabio

A faster, smaller, better way to qPCR

Supplier: NABERTHERM INC.

Due to their maximum temperature of 1650 °C and their large chamber, these high-temperature bottom loading furnaces are perfectly suited for sintering translucent zirconia. The motor-driven lifting table significantly simplifies the charging of the high-temperature furnace. The all-around heating of the cylindrical furnace chamber ensures a very even temperature uniformity.

Supplier: Celestron International

The NexYZ DX Kit is a great first step into the world of astroimaging or digiscoping.

Supplier: Upchurch Scientific

It is good practice to filter solvents to prevent pump and other system component damage.

Supplier: SENSEANYWHERE BV

The SenseAnywhere 0 - 10 V input module digitizes analogue products with a 0 - 10 V output, ensuring high-precision measurements for variables like CO₂ and dust particles. Integrated electronics with a SAB interface allow individual module calibration. Its hot-swappable feature ensures continuous, accurate monitoring without data loss.

Supplier: Prosci

Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF).