28362 Results for: "4,7,10-Trioxatetracyclo[5.2.1.0(2,6).0(8,10)]undecan-3-one"

Supplier: Sonoco Thermosafe

Medical transporter totes for on-site collection, storage, and transportation of temperature-sensitive specimens, organs, medications, and medical devices.

Supplier: Prosci

This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TECK displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. TECK binds to chemokine receptor CCR9. Two alternatively spliced variants encoding two different isoforms have been identified.

Supplier: Cytiva

Cytiva's Whatman PM2.5 PTFE membrane filters are designed for PM 2.5 ambient air monitoring. These high-purity, thin filters are sequentially numbered and come with chemically resistant polypropylene support rings.

Supplier: SPEX CERTIPREP LLC

Mobile phase modifiers are conveniently packaged for error-free use. Our ampules contain precisely measured aliquots of high purity modifiers which are designed to be directly added to mobile phase reservoirs for easy use.

Supplier: Electron Microscopy Sciences

The new improved Kimball Physics Model ES-423E (Extended Life) LaB6 Cathode is a high performance, resistively heated, thermionic electron source. The improvement stability of the LaB6 crystal, results in less exposure of LaB6, which reduces Wehnelt aperture contamination. It is for use in Scanning Electron Microscopes, Transmission Electron Microscopes, Electronlithography Systems, and X-Ray Sources.

Supplier: Prosci

NAP2 is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.

Supplier: Thermo Scientific

Thermo Scientific Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits.

Supplier: Avantor

The NASA’s Beginning Engineering, Science and Technology (BEST) Students Kit was designed to accompany the NASA BEST Students Educator guides, an afterschool engineering club curriculum for students in grade K to 2, 3 to 5 and 6 to 8 (www.nasa.gov/audience/foreducators/best/index.html).

Supplier: VWR International

Fast-reading, easy-to-use thermometer switches from °C to °F at the touch of a button.

Supplier: VWR

The VWR® PCR thermal cycler XT⁹⁶ combines industry-inspired innovation with the reliable quality of German manufacturing – housing both in a compact, low noise ventilation design that fits on virtually any bench top. For optimising PCR's, the XT⁹⁶ is also available with a gradient function.
The VWR® PCR thermal cycler XT⁹⁶ offers a powerful, yet easy to use software interface, as well as a host of other innovative features.

Supplier: Bioss

The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].

Supplier: SENSEANYWHERE BV

The Hermetically Sealed Pt100 Probe, with a digital SenseAnywhere Bus and PFA seal, specializes in extreme temperature measurements in liquids, from –90 to +250 ˚C. Chemical-resistant and waterproof, it's perfect for harsh environments. It requires calibration only for the probe, with easy monitoring via the SenseAnywhere Portal.

Supplier: Biotium

P53, Monoclonal antibody, Clone: BP53-12, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, Conjugate: CF405S, Immunogen: Recombinant human TP53 protein, Synonyms: Antigen NY-CO-13, BCC7, Cellular Tumor Antigen p53, Application: IF, IHC (formalin), Western, Size: 500uL

Supplier: Thermo Scientific

Thermo Scientific Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits.

Supplier: Thermo Scientific

Thermo Scientific Heavy and Light Amino Acids are used to specifically analyze protein expression by mass spectrometry using stable isotope labeling with amino acids in cell culture (SILAC) quantification kits.

Supplier: Cytiva

MBS I is an excellent system for optimal microbiological control using membranes. The overall procedure time is reduced to a minimum. The design of the system, which consists of an electrical membrane dispenser, a funnel dispenser, and a vacuum manifold, leads to more reproducible results. All components are sold separately. The modular system provides flexibility to select the hardware and accessories that best suit the unique and varied workflows of the user.
The special sealing technique ensures easy handling and high integrity of the funnel and membrane during filtration. This keeps any cross-contamination to a minimum.

Supplier: NABERTHERM INC.

Due to their solid construction and compact stand-alone design, these high-temperature furnaces are perfect for processes in the laboratory where the highest precision is needed.

Supplier: Prosci

Flt3-Ligand is a growth factor important for the proliferation of hematopoietic cells. Flt3-Ligand binds to, and transmits signals through, the receptor tyrosine kinase known as FMS-like Tyrosine Kinase-3 (FLT-3). Flt3-Ligand promotes long-term expansion and differentiation of human pro-B-cells in the presence of IL-7 or in combination of IL-7 and IL-3. Human Flt3-Ligand can stimulate the proliferation of cells expressing murine FLT-3 receptors.

Supplier: Prosci

Macrophage Inflammatory Protein 1 alpha and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation.

Supplier: Electron Microscopy Sciences

The system includes four Blocklock modules which can be fixed to mounting panels for 3-ring binders or can be stored into Blocklock storage boxes.

Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA

AdvanceBio N-Glycanase (PNGase F), ≥2.5 U/mL (formerly ProZyme). A recombinant form of PNGase F, releases intact N-glycans by cleaving between the innermost GlcNAc and Asn. Includes 5x N-glycanase reaction buffer, denaturation solution, detergent solution, 5x N-glycanase Tris reaction buffer (MS applications). Supplied at a concentration of ≥ 2.5 U/mL. For a more concentrated formulation of ≥ 10 U/mL, which may be useful for native digestions, see GKE-5010B or GKE-5020B (EDTA-free).

Supplier: CUBE BIOTECH

The Ultrasolute family evolved from the first amphipol A8-35 is used for highly efficient solubilization and stabilization of membrane proteins without the use of detergents while preserving their activity. They demonstrate tolerance to moderate concentrations of divalent cations and exhibit no absorption at wavelengths >250 nm.

Supplier: Enzo Life Sciences

It is a complete assay system designed to screen inhibitors of neutrophil elastase, providing enough material to perform at least 96 assays. Neutrophil elastase, also known as leukocyte elastase (LE), is a serine protease found in polymorphonuclear neutrophils (PMNs) that functions in inflammation. It can cleave a variety of proteins, including fibrous elastin, collagen, clotting factors, TNF-α, and α1-antichymotrypsin. It has been shown to be taken up by tumor cells and accelerate tumor growth through its degradation of insulin receptor substrate-1 (IRS-1). Because of its potential roles in cancer and inflammatory diseases such as emphysema, cystic fibrosis, and atherosclerosis, it is a target for drug discovery. The kit uses the chromogenic substrate MeOSuc-Ala-Ala-Pro-Val-pNA; cleavage of p-nitroaniline (pNA) from the substrate increases absorbance at 405nm. A neutrophil elastase inhibitor, elastatinal, is included for use as a control.

Supplier: TrippNT

Workstations and organizers for storage of commonly used laboratory items.

Supplier: Prosci

Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation. Thus synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 9 is the site on synapsin I that is phosphorylated by cAMP-dependent protein kinase and by calcium calmodulin kinase I. Phosphorylation of this site is thought to regulate synaptic vesicle function.

Supplier: Prosci

Iterleukin 7 is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells. IL-7 was previously known as pre-B cell growth factor and lymphopoietin 1. IL-7 supports the growth of early B cells from long-term lymphoid bone marrow cultures. It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA). IL-7 stimulates the proliferation of CD4+/CD8+ cells.

Supplier: Bel-Art Products, a Part of SP

Made from optical quality polycarbonate plastic material, these plain form hydrometers are durable and shatterproof, and perfect for field work where breakage could be a concern.

Supplier: Wards

The Quantitative Centripetal Force Apparatus' simple concept and robust construction guarantee reliable lab success.

Supplier: Prosci

There is accumulating evidence to suggest that progesterone plays an essential role in the regulation of growth and differentiation of mammary glands and thus may play a key role in breast cancer. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (A and B forms). In most cell contexts, the B form functions as a transcriptional activator, whereas the A form functions as a transcriptional inhibitor of steroid hormones. Recently it has been demonstrated that there is differential hormone dependent regulation of the phosphorylation of the A and B forms of the receptor. Treatment of T47D breast cancer cells with progestin agonist increases the phosphorylation of Ser190 and Ser294 with different kinetics. These phosphorylation events may differentially affect the transcriptional activity of the receptor.

Supplier: Prosci

IL-9 is a cytokine preferentially produced by T helper type 2 lymphocytes and active on various cell types such as T and B lymphocytes, mast cells and haemopoietic progenitors; but no effect of this cytokine has been reported so far on mononuclear phagocytes. IL-9 stimulates cell proliferation and prevents apoptosis. The IL-9 receptor (IL 9R) belongs to the haemopoietic receptor superfamily and its signal transduction involves mainly the (JAK/STAT) pathway. Some studies have implicated IL-9 as an important cytokine in a number of Th2 cytokine mediated pathologies, in particular asthma