11791 Results for: "4,4-Di-n-octylthieno[3,2-b"
Corrected to: 4,4-Di-n-octylpheno[3,2-b
Anti-ANP32A Rabbit Polyclonal Antibody
Supplier: Prosci
PHAP I Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
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Anti-LRRC32 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: GARP5]
Supplier: Tonbo Biosciences
The GARP5 antibody reacts with human GARP, also known as LRRC32 or Garpin, an 80 kDa transmembrane protein which acts as a receptor for the latent form of TGF-beta 1 (pro-TGF-beta), preventing its secretion. Specifically, GARP is reported to associate with the pro-domain of TGF-beta 1, known as latency-associated peptide (LAP), which must be cleaved to release the biologically active cytokine. The putative role of GARP in sequestering the TGF-beta is important for regulating its activity, as TGF-beta signaling is involved in development and function of Th17, Treg and many other immune cell types. GARP expression has been shown on platelets and at high levels on Foxp3+ Treg cells, where it is proposed to be a phenotypic identifier for activated human Treg cells.
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Ranger® Industrial Bench Scale
Supplier: Ohaus
Top-of-the-line compact scales for even the most complex industrial applications. Simplify complex applications and minimize the need for manual calculations with ten advanced application modes, peripheral device control and an optional kit for a second scale platform.
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Anti-ANP32A Rabbit Polyclonal Antibody
Supplier: Prosci
PHAP Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
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Anti-DHX32 Rabbit Polyclonal Antibody (Cy7®)
Supplier: Bioss
DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX32 is a 743 amino acid nuclear protein that localizes to the mitochondria and is a member of the DEAD box helicase family. Expressed in various tissues, DDX32 is up-regulated by ionomycin in T lymphocytes and down-regulated in acute lymphoblastic leukemia. Considered a novel RNA helicase, DDX32 may play an important role in the development of colorectal cancer and may be involved in regulating T-cell response to certain apoptotic stimuli.
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MS Series High Capacity Balances, Mettler-Toledo
Supplier: Mettler Toledo
The NewClassic MS series top-loading, high-capacity balances offer quality in an economical package.
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Anti-ANP32A Rabbit Polyclonal Antibody
Supplier: Prosci
PHAP I Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
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Ward's® AP Biology Investigation 5: Cell Processes: Photosynthesis
Supplier: Avantor
Meets AP Science Practices 1, 2, 3, 6, and 7
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Ward's® AP Biology Investigation 8: Genetics and Information Transfer: Transformation
Supplier: Avantor
Meets AP Science Practices 1, 3, 5, 6, and 7, and Big Idea 3.
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Ultra-Low Temperature Freezers, TSX Universal -86 °C ULT
Supplier: Thermo Fisher Scientific
TSX Universal series ULT freezers are the pinnacle of reliability, sustainability, and innovation incorporating insights from over 80 years of experience to enhance every aspect of the system. Updates to the variable speed compressors has made the TSX Universal adaptable across all workflows. Available in four capacities, they are ENERGY STAR® certified with a 33% energy efficiency improvement, ACT labeled and produced in a Zero-Waste to Landfill certified facility.
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Moxi™ Z Mini Automated Cell Counter
Supplier: Orflo
The Moxi™ Z automated cell counter combines the the “gold-standard” Coulter Principle typically used in high-end instruments with a patented thin-film sensor technology to provide highly accurate and repeatable direct cell/particle size and count over a broad dynamic range (2-34 microns), with single cell resolution
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XPert™ Weigh Box, Labconco®
Supplier: Labconco
Weigh box features inlet and outlet HEPA filters that help provide a leak-tight physical barrier to protect the operator from hazardous airborne particulates and powders (99.99% efficiency on 0.3µm particulates)
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Anti-LEP Mouse Monoclonal Antibody [clone: G1_4B6.3]
Supplier: Prosci
Leptin plays a critical role in the regulation of body weight by inhibiting food intake and stimulating energy expenditure. Defects in Leptin production cause severe hereditary obesity in rodents and humans. In addition to its effects on body weight, leptin has a variety of other functions, including the regulation of hematopoiesis, angiogenesis, wound healing, and the immune and inflammatory response. The Leptin gene is the human homolog of the gene (ob) mutant in the mouse 'obese' phenotype.
Was product number XP-5712-M
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Adventurer® AX Analytical Balances, Ohaus®
Supplier: Ohaus
The Adventurer® AX Analytical balance series strike the ideal mix between inventive features, long-lasting durability, and uncomplicated weighing capabilities.
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Ward's® AP Biology Investigation 4: Cell Processes: Diffusion and Osmosis
Supplier: Avantor
Meets AP Science Practices 2, 4, and 5, and Big Idea 2.
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Model SU105UE Ultra-Low Temperature Undercounter Freezer, Stirling Ultracold, Global Cooling
Supplier: Stirling Ultracold
The SU105UE is a compact ultra-low temperature freezer that is ideal for personal storage and situations where larger volume ULT freezers might otherwise remain half empty.
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Anti-RNF32 Rabbit Polyclonal Antibody
Supplier: Prosci
RNF32 contains two RING ring finger motifs. RING finger motifs are present in a variety of functionally distinct proteins and are known to be involved in protein-DNA or protein-protein interactions. Its gene was found to be expressed during spermatogenesis, most likely in spermatocytes and/or in spermatids.The protein encoded by this gene contains two RING ring finger motifs. RING finger motifs are present in a variety of functionally distinct proteins and are known to be involved in protein-DNA or protein-protein interactions. This gene was found to be expressed during spermatogenesis, most likely in spermatocytes and/or in spermatids. Several alternatively spliced transcript variants exist, but their full length natures are not clear.
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Anti-LRRC32 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: GARP5]
Supplier: Tonbo Biosciences
The GARP5 antibody reacts with human GARP, also known as LRRC32 or Garpin, an 80 kDa transmembrane protein which acts as a receptor for the latent form of TGF-beta 1 (pro-TGF-beta), preventing its secretion. Specifically, GARP is reported to associate with the pro-domain of TGF-beta 1, known as latency-associated peptide (LAP), which must be cleaved to release the biologically active cytokine. The putative role of GARP in sequestering the TGF-beta is important for regulating its activity, as TGF-beta signaling is involved in development and function of Th17, Treg and many other immune cell types. GARP expression has been shown on platelets and at high levels on Foxp3+ Treg cells, where it is proposed to be a phenotypic identifier for activated human Treg cells.
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Anti-LRRC32 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: GARP5]
Supplier: Tonbo Biosciences
The GARP5 antibody reacts with human GARP, also known as LRRC32 or Garpin, an 80 kDa transmembrane protein which acts as a receptor for the latent form of TGF-beta 1 (pro-TGF-beta), preventing its secretion. Specifically, GARP is reported to associate with the pro-domain of TGF-beta 1, known as latency-associated peptide (LAP), which must be cleaved to release the biologically active cytokine. The putative role of GARP in sequestering the TGF-beta is important for regulating its activity, as TGF-beta signaling is involved in development and function of Th17, Treg and many other immune cell types. GARP expression has been shown on platelets and at high levels on Foxp3+ Treg cells, where it is proposed to be a phenotypic identifier for activated human Treg cells.
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MAC Auger Electron Microscopy Standards, Electron Microscopy Sciences
Supplier: Electron Microscopy Sciences
MAC has developed multi-element blocks of reference materials suitable for the compilation of a reference library of Auger sensitivity factors when used with the Auger Electron Microscopy (AES). (Auger electron: one of the electrons ejected from an atom as a result of the internal conversion of its own X-ray in the auger effect. Auger effect: a process in which an atom singly ionized by emitting one electron with energy in the X-ray range instead of emitting the usual X-ray photon on recovery undergoes a transition in which a second electron is emitted).
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Globe Glass™ Media Bottles, Globe Scientific
Supplier: Globe Scientific
Globe Glass™ media bottles are designed with a wide mouth for ease of filling, dispensing, and pipetting. A drip-free pour ring and autoclavable polyethylene (PE) screw cap enable the sterilization of media and reagents. Globe Glass™ media bottles are available in sizes ranging from 50 to 10000 ml.
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Precise™ Controlled Atmosphere Glove Box, Labconco®
Supplier: Labconco
Designed to provide a leak-tight environment for work with contamination-sensitive materials
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Accucold® Vaccine Freezers, ADA Height
Supplier: FELIX STORCH, INC./SUMMIT
Purpose-built all-freezers for vaccine storage in medical, pharmaceutical and life science applications.
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Anti-ANP32E Rabbit Polyclonal Antibody
Supplier: Prosci
PHAP III Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
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Anti-rh BDNF Rabbit Polyclonal Antibody
Supplier: Biosensis
BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. Post Translation Modification (PTM): The propeptide is N-glycosylated and glycosulfated. PTM: Converted into mature BDNF by plasmin (PLG) (By similarity). DISEASE: Defects in BDNF are a cause of congenital central hypoventilation syndrome (CCHS); also known as congenital failure of autonomic control or Ondine curse. CCHS is a rare disorder characterized by abnormal control of respiration in the absence of neuromuscular or lung disease, or an identifiable brain stem lesion. A deficiency in autonomic control of respiration results in inadequate or negligible ventilatory and arousal responses to hypercapnia and hypoxemia. CCHS is frequently complicated with neurocristopathies such as Hirschsprung disease that occurs in about 16% of CCHS cases. SIMILARITY: Belongs to the NGF-beta family.
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VWR® Traceable® Digital Thermometer
Supplier: VWR International
Ideal for measuring temperatures in cuvettes, gas systems, reagents, and chemical solutions, or for routine measurements.
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Roto-Shake Genie™ 6–in–1 Multi-Purpose Rotator Rocker, 230 V
Supplier: Scientific Industries
Space-saving multi-action platform rotator/rocker produces six different mixing motions: rotating, rotating/rocking, rotating/rolling, rolling/rocking, and rocking/shaking, as well as a combination of all of these.
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Ward's® AP Biology Investigation 9: Genetics and Information Transfer: Restriction Enzymes
Supplier: Avantor
Meets AP Science Practices 3 and 6
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XPert™ Bulk Powder Filtered Stations, Labconco®
Supplier: Labconco
Bulk powder stations are designed to protect the user from airborne particulates and fumes generated during powder transfer operations
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Precise™ HEPA-Filtered Glove Box, Labconco®
Supplier: Labconco
Glove box features inlet and outlet HEPA filters (99.99% efficiency on 0.3µm particulates) and provides a leak-tight physical barrier to protect the operator from hazardous airborne particulates and powders