5969 Results for: "3,5-dichlorobenzenesulfonamido"

Supplier: Prosci

The Galectin family of proteins (with specificity for Nacetyllactosamine containing glycoproteins) consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). At least 14 mammalian galectins family members that share structural similarities in their carbohydrate recognition domains (CRD) have been identified to date. Unlike the selectin family of proteins, the carbohydrate binding specificity of galectins is calcium-independent. A common function of galectins is to cross-link structures containing N-acetyl-lactosamine located at the cell surface and within the extracellular matrix. They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. They have diverse effects on many cellular functions including adhesion, migration, polarity, chemotaxis, proliferation, apoptosis, and differentiation. Galectins may therefore play a key role in many pathological states, including autoimmune diseases, allergic reactions, inflammation, tumor cell metastasis, atherosclerosis, and diabetic complications. The galectins have been classified into the prototype galectins (1, 2, 5, 7, 10, 11, 13, 14), which contain one CRD and exist either as a monomer or a noncovalent homodimer. The chimera galectins (Galectin3) containing one CRD linked to a nonlectin domain, and the tandem repeat Galectins (4, 6, 8, 9, 12) consisting of two CRDs joined by a linker peptide. Galectins lack a classical signal peptide and can be localized to the cytosolic compartments where they have intracellular functions. However, via one or more as yet unidentified nonclassical secretory pathways, galectins can also be secreted to function extracellularly. Individual members of the galectin family have different tissue distribution profiles and exhibit subtle differences in their carbohydrate-binding specificities. Each family member may preferentially bind to a unique subset of cell surface glycoproteins.

Supplier: Desco

Statshield® Smock Lab Coat with Knitted Cuffs are a groundable static control garment system.

Supplier: Electron Microscopy Sciences

A new series of sterile, optical quality, glass bottom dishes which provide exceptional imaging quality for many applications requiring the use of inverted microscopes.

Supplier: BLICKMAN INDUSTRIES

Warming cabinets are constructed with quality 304 stainless steel, #4 polish and have a seamless welded face preventing dirt collection while providing long lasting durability through unparalleled strength and corrosion resistance. This line of warming cabinets includes single chamber, dual chamber, tabletop, under-counter, and recessed models (including a pass-through version with doors on the front and back).

Supplier: Eco Lab

The Bioquell L-4 is a mobile Hydrogen Peroxide Vapor bio-decontamination generator that can be connected to enclosures, equipment, isolators and more in your facility or, with additional accessories, be used for room/zone bio-decontamination.

Supplier: Caron Products

With full visible and UVA ICH Q1B exposures in as little as 42 hours, the 7450 series provides results fast. Many competing chambers take 2 to 3 times as long. Fast photoexposure allows users to test more samples, reducing drug development time, and saving money.

Supplier: Genetex

Mouse monoclonal [61016.11] to Eotaxin 2

Supplier: Desco

Statshield® Smock Jacket with Snaps are a groundable static control garment system.

Supplier: Biotium

TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF568, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 100uL

Supplier: Argos Technologies

Variable speed mixer designed for reliability and durability.

Supplier: Prosci

TRIM35 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM35 may play a role as a tumor suppressor, and is implicated in the cell death mechanism.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified.

Supplier: Justrite

This Double Cylinder Hand Truck with Firewall and Hoist Ring provides safety when moving and storing of gas cylinders.

Supplier: Biotium

MHC II (HLA-DQ), Monoclonal antibody, Clone: SPV-L3, Host: Mouse, Species reactivity: Human, Pig, Isotype: IgG2a, kappa, Conjugate: CF405S, Immunogen: T4-positive CTL clone HG-38, Application: Immunofluorescence, Flow cytometry, Size: 500uL

Supplier: Desco

Statshield® Smock Lab Coat with Snaps are a groundable static control garment system.

Supplier: National Public Seating

High-quality premium vinyl upholstered stack chairs available in choice of institutional grade fabrics or thick 0.80 mm vinyl.

Supplier: Prosci

SLC35D3 Antibody: The solute carrier family SLC35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The novel protein SLC35D3 is highly homologous to SLC35D1 and SLC35D2, both of which transport UDP-glucuronic acid and UDP-N-acetylgalactosamine, suggesting that SLC35D3 is also involved in the transport of nucleotide sugars. It has been suggested that SLC35D3 regulates platelet dense granules, lysosome-related organelles which contain high concentrations of several biologically important low molecular weight molecules necessary for normal blood homeostasis.

Supplier: Biotium

CD74 Monoclonal antibody, Clone: CLIP/1133, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recombinant full-length human CD74 protein, Application: IF, Western, FC, Size: 100uL

Supplier: Biotium

TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF488A, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 500uL

Supplier: Biotium

TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF594, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 100uL

Supplier: Thermo Scientific

Thermo Scientific SulfoLink Coupling Resin is porous, crosslinked, 6% beaded agarose that has been activated with iodoacetyl groups for covalent immobilization of cysteine-peptides and other sulfhydryl molecules.

Supplier: Prosci

IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN- gamma ) and tumor necrosis factor-alpha (TNF- alpha) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN- gamma . T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.

Supplier: Biotium

TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF647, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 500uL

Supplier: Biotium

TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF640R, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 500uL

Supplier: ROEMER INDUSTRIES, INC.

PlasmaRoam 20 is a portable plasma freezer for field collections of temperature sensitive biological items, units have optional accessories such as wheels and data management. This unit can be secured with a padlock can be stacked with stacking corners, it has handles on the side but is too heavy for a single person to carry. Most customers purchase units together with casters or dolly trolley. Excellent for disaster preparedness to store temperature sensitive products when the electrical power supply is not reliable or dependable.

Supplier: VWR International

Storage and Content all in one!

Supplier: Biotium

TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF405S, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 100uL

Supplier: Desco

Statshield® Smock Jacket with Knitted Cuffs is a groundable static control garment system.

Supplier: AEROLITE METEORITES INC SE

Bundle and save on these cosmic wonders.

Supplier: Thermo Scientific

The Epredia™ HM 525 NX series of Cryostats offer exceptional sectioning quality and reliability, an intuitive user interface, and enhanced ergonomics for simple, efficient operation.

Supplier: Prosci

Slc35D1 Antibody: The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.