6269 Results for: "2,4,6-Tris(4-fluorophenyl)boronic"
Anti-ALOX15 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Supplier: Bioss
Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.
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Anti-ALOX15 Rabbit Polyclonal Antibody (Cy5.5®)
Supplier: Bioss
Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.
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PageRuler™ Unstained Low Range Protein Ladder
Supplier: Thermo Scientific
Thermo Scientific PageRuler Unstained Low Range Protein Ladder is a mixture of seven (7) purified proteins and peptides (3.4 to 100kDa) for use as size standards in peptide and small-protein gel electrophoresis.
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Let’s enhance safety by considering personalized protection equipment (PPE) solutions tailored to your team, processes, and products.
Pierce™ Magnetic RNA-Protein Pull-Down Kit, Thermo Scientific
Supplier: Thermo Scientific
The Thermo Scientific Pierce Magnetic RNA-Protein Pull-Down Kit provides researchers with a streamlined, robust method to enrich protein-RNA interactions using end-labeled RNA as the bait.
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Human Recombinant ACTG1 (from E. coli)
Supplier: Prosci
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, α, β and γ have been identified. The α actins are found in muscle tissues and are a major constituent of the contractile apparatus. The β and γ actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, γ 1, encoded by this gene, is a cytoplasmic actin found in nonmuscle cells.
FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
SUBUNIT: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
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Mouse Recombinant ATG7 (from E. coli)
Supplier: Prosci
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1 (3). Another member of the autophagy family of proteins is APG7 which was identified in yeast as a ubiquitin-E1-like enzyme; this function is conserved in the mammalian homolog (4). In mammalian cells, APG7 is essential for autophagy conjugation systems, autophagosome formation, starvation-induced bulk degradation of proteins and organelles (5). It has been suggested that caspase-8 may alter APG7 levels and thus the APG7 program of autophagic cell death (6).
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Nucleofector® P3 Primary Cell 96-well Kit
Supplier: LONZA PHARMA - BIOSCIENCE CA
The P3 Primary Cell 96-well Nucleofector® kit is one of our five kits suited for medium-throughput transfection of primary cells when working with the 4D-Nucleofector® 96-well unit.
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Whatman™ Grade 4V Qualitative Filter Papers, Whatman products (Cytiva)
Supplier: Cytiva
Whatman Grade 4V filter paper is well suited for qualitative analysis or general filtration of coarse particles. The fluted filter design increases filtration speed, flow rate, and loading capacity.
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Anti-ALOX15 Rabbit Polyclonal Antibody (Cy7®)
Supplier: Bioss
Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.
Expand 1 Items
Anti-ALOX15 Rabbit Polyclonal Antibody (Cy5®)
Supplier: Bioss
Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.
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2-D Quant Kit, Cytiva
Supplier: Cytiva
2-D Quant Kit is designed for the accurate determination of protein concentration in samples prepared for electrophoresis techniques such as 2-D electrophoresis, SDS-PAGE, or IEF.
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PureCube DIBMA Glycerol, Screening Kit, HEPES
Supplier: CUBE BIOTECH
DIBMA stands for diisobutylene maleic acid copolymer, and is an extensively researched polymer. The fundamental properties of DIBMA include the absence of light absorption at a wavelength >250 nm, a crucial factor for protein detection via absorbance, and a high resistance to divalent cations.
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PageRuler™ Unstained Broad Range Protein Ladder
Supplier: Thermo Scientific
Thermo Scientific PageRuler Unstained Broad Range Protein Ladder is a mixture of 11 proteins (5kDa to 250kDa) for use as size standards in protein electrophoresis (SDS-PAGE) and Western blotting.
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Nucleofector® AD2 4D-Y Kit
Supplier: LONZA PHARMA - BIOSCIENCE CA
Electroporation-based methods have so far required cells to be in suspension for transfection. However, the 4D-Nucleofector® Y Unit allows direct Nucleofection of cells in adherence. Cells which typically grow in adherence in cell culture, can be kept and transfected by Nucleofection in their physiological state.
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Anti-ALOX15 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Supplier: Bioss
Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.
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Anti-ALOX15 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Supplier: Bioss
Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.
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Nucleofector® Cell Line Optimization 4D-X Kit
Supplier: LONZA PHARMA - BIOSCIENCE CA
The cell line optimization 4D-Nucleofector® X kit is the ideal tool to conveniently and rapidly determine Nucleofection conditions for cell lines lacking an optimized protocol for the 4D-Nucleofector® X unit.
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Anti-B2M Mouse Monoclonal Antibody [clone: B2M-01]
Supplier: Genetex
PE-conjugated Mouse Monoclonal antibody [B2M-01] to beta2-microglobulin
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ALDetect™ (MDA-Specific) Lipid Peroxidation Assay Kit, Enzo Life Sciences
Supplier: Enzo Life Sciences
Lipid peroxidation is a well-established mechanism of cellular injury in both plants and animals, and is used as an indicator of oxidative stress in cells and tissues. Lipid peroxides, derived from polyunsaturated fatty acids, are unstable and decompose to form a complex series of compounds. These include reactive aldehydes, of which the most abundant is malondialdehyde (MDA). Therefore, measurement of malondialdehyde is widely used as an indicator of lipid peroxidation. Increased levels of lipid peroxidation products have been associated with a variety of chronic diseases in both humans and model systems.
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Shimpo Data-Logging Contact/Non-Contact Handheld Tachometer, SEALS USA INC
Supplier: Nidec Shimpo America
The Series DT-2100 Data-Logging Tachometer is the most highly advanced tachometer ever developed by NIDEC-SHIMPO.
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Anti-PSEN1 Rabbit Polyclonal Antibody
Supplier: Biosensis
Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot).
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Pierce™ Immunoprecipitation, Classic IP Kit, Thermo Scientific
Supplier: Thermo Scientific
The Thermo Scientific Pierce™ classic IP kit uses high-quality Protein A/G agarose beads, microcentrifuge spin columns and buffers to perform traditional immunoprecipitation assays with ease.
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Nucleofector® Human Stem Cell Kit 1
Supplier: LONZA PHARMA - BIOSCIENCE CA
The Nucleofector® 2b device (or older generations I or II) works with cell type specific kits, each of them dedicated to an individual primary cell. The Human Stem Cell Nucleofector® kit 1 is one of our two kits suited for efficient transfection of human stem cells.
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Pierce™ Glutathione Spin Columns, Thermo Scientific
Supplier: Thermo Scientific
These Glutathione spin columns provide a fast, easy-to-use format to purify GST-fusion proteins from cellular lysates.
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8270 Calibration Kit, Restek
Supplier: Restek
Contains 1 ml each of the followig mixtures, 8270 calibration mix #1, 8270 calibration mix #2, 8270 calibration mix #3, 8270 calibration mix #4, 8270 calibration mix #5 revised and 3-methylcholanthrene standard.
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Anti-Nicastrin, C-terminal domain Rabbit Polyclonal Antibody
Supplier: Biosensis
Nicastrin, a type 1 membrane glycoprotein, is an essential component of the gamma secretase complex which is critical for the cleavage of the amyloid precursor protein and other membrane proteins. Nicastrin is widely expressed in different tissue types. This antibody detects all processed forms of Nicastrin.
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Anti-Nicastrin, N-terminal domain Rabbit Polyclonal Antibody
Supplier: Biosensis
Nicastrin, a type 1 membrane glycoprotein, is an essential component of the gamma secretase complex which is critical for the cleavage of the amyloid precursor protein and other membrane proteins. Nicastrin is widely expressed in different tissue types. This antibody detects all processed forms of Nicastrin.
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Anti-ALOX15 Rabbit Polyclonal Antibody (Cy3®)
Supplier: Bioss
Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.
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RT-PCR beads, illustra™ Ready-To-Go™
Supplier: Cytiva
Pre-dispensed, freeze-dried beads that include the reagents necessary for one-step reverse transcription-PCR with high sensitivity and reproducibility.
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AccuStart™ II Taq DNA Polymerase, QuantaBio
Supplier: Quantabio
AccuStart™ II Taq DNA Polymerase is a high purity, recombinant Taq DNA polymerase preparation with high avidity monoclonal antibodies that bind the polymerase and keep it inactive prior to the initial PCR denaturation step