1615 Results for: "11-bromoundecanol acid"
Corrected to: 11-bromoundecane acid
Anti-PTPN11 Rabbit Polyclonal Antibody
Supplier: Prosci
SHP2 Antibody: Src homology-2 domain containing protein (SHP2) is a member of the protein tyrosine phosphatase (PTP) family, a protein family that contains signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. SHP2 contains two tandem Src homology-2 (SH2) domains, which function as phosphotyrosine binding domains either directly or through scaffolding intermediates such as the insulin-receptor substrate 1 (IRS-1). These SH2 domains mediate the interaction of SHP2 with its substrates, allowing SHP2 to dephosphorylate proteins that inhibit signaling kinases such as ERK1 and AKT. SHP2 is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Recent experiments have shown SHP2 plays a significant role in hepatoprotection and liver regeneration.
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Whatman™ TurboBlotter Kits and Refills, Whatman products (Cytiva)
Supplier: Cytiva
The TurboBlotter™ system is a rapid, downward blotting device for high-resolution transfer of DNA and RNA. The conventional Northern/Southern transfer stack has been turned upside down in order to take advantage of gravity.
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Anti-ADAM11 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Supplier: Bioss
ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries, in search of brain-specific proteins. Two splice variants with different carboxyterminal ends were described. The message was found only in the brain in this publication. Another group identified ADAM11 in the human brain, where ADAM11 was thought to be involved in cell migration and spatial patterning. ADAM11 was mapped to 17q21.3, a region of interest for breast cancer, and mutations in ADAM11 are associated with some breast cancers. Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, a human embryonic carcinoma cell line. ADAM11 null mutant mice have deficits in spatial learning and motor coordination, although they did have normal cell migration and differentiation during development. ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full-length ADAM11 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a spacer region, then the transmembrane domain and a short cytoplasmic domain.
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Anti-ADAM11 Rabbit Polyclonal Antibody (Cy7®)
Supplier: Bioss
ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries, in search of brain-specific proteins. Two splice variants with different carboxyterminal ends were described. The message was found only in the brain in this publication. Another group identified ADAM11 in the human brain, where ADAM11 was thought to be involved in cell migration and spatial patterning. ADAM11 was mapped to 17q21.3, a region of interest for breast cancer, and mutations in ADAM11 are associated with some breast cancers. Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, a human embryonic carcinoma cell line. ADAM11 null mutant mice have deficits in spatial learning and motor coordination, although they did have normal cell migration and differentiation during development. ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full-length ADAM11 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a spacer region, then the transmembrane domain and a short cytoplasmic domain.
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Anti-ADAM11 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Supplier: Bioss
ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries, in search of brain-specific proteins. Two splice variants with different carboxyterminal ends were described. The message was found only in the brain in this publication. Another group identified ADAM11 in the human brain, where ADAM11 was thought to be involved in cell migration and spatial patterning. ADAM11 was mapped to 17q21.3, a region of interest for breast cancer, and mutations in ADAM11 are associated with some breast cancers. Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, a human embryonic carcinoma cell line. ADAM11 null mutant mice have deficits in spatial learning and motor coordination, although they did have normal cell migration and differentiation during development. ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full-length ADAM11 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a spacer region, then the transmembrane domain and a short cytoplasmic domain.
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Anti-ADAM11 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Supplier: Bioss
ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries, in search of brain-specific proteins. Two splice variants with different carboxyterminal ends were described. The message was found only in the brain in this publication. Another group identified ADAM11 in the human brain, where ADAM11 was thought to be involved in cell migration and spatial patterning. ADAM11 was mapped to 17q21.3, a region of interest for breast cancer, and mutations in ADAM11 are associated with some breast cancers. Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, a human embryonic carcinoma cell line. ADAM11 null mutant mice have deficits in spatial learning and motor coordination, although they did have normal cell migration and differentiation during development. ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full-length ADAM11 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a spacer region, then the transmembrane domain and a short cytoplasmic domain.
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Anti-ADAM11 Rabbit Polyclonal Antibody
Supplier: Bioss
ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries, in search of brain-specific proteins. Two splice variants with different carboxyterminal ends were described. The message was found only in the brain in this publication. Another group identified ADAM11 in the human brain, where ADAM11 was thought to be involved in cell migration and spatial patterning. ADAM11 was mapped to 17q21.3, a region of interest for breast cancer, and mutations in ADAM11 are associated with some breast cancers. Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, a human embryonic carcinoma cell line. ADAM11 null mutant mice have deficits in spatial learning and motor coordination, although they did have normal cell migration and differentiation during development. ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full-length ADAM11 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a spacer region, then the transmembrane domain and a short cytoplasmic domain.
Expand 1 Items
Anti-PTPN11 Rabbit Polyclonal Antibody
Supplier: Prosci
SHP2 Antibody: Src homology-2 domain containing protein (SHP2) is a member of the protein tyrosine phosphatase (PTP) family, a protein family that contains signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. SHP2 contains two tandem Src homology-2 (SH2) domains, which function as phosphotyrosine binding domains either directly or through scaffolding intermediates such as the insulin-receptor substrate 1 (IRS-1). These SH2 domains mediate the interaction of SHP2 with its substrates, allowing SHP2 to dephosphorylate proteins that inhibit signaling kinases such as ERK1 and AKT. SHP2 is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Recent experiments have shown SHP2 plays a significant role in hepatoprotection and liver regeneration.
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Anti-SPG11 Rabbit Polyclonal Antibody
Supplier: Prosci
SPG11 Antibody: Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders. Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia (cHSP) in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration. Mutations of the SPG11 gene encoding the spatacsin protein have been identified as a major cause of HSP-TCC. Spatacsin is a potential transmembrane protein that is phosphorylated upon DNA damage. It is expressed in all structures of the brain, with a high expression in the cerebellum. SPG11 mutations may occur more frequently in familial than sporadic forms of cHSP without TCC. Kjellin syndrome is found to be associated with mutations in not only the SPG15 gene but also SPG11 gene. Recent studies show Parkinsonism may initiate SPG11-linked HSP TCC and that SPG11 may cause juvenile Parkinsonism.
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SP Wilmad-LabGlass Thin Walled Quartz NMR Tubes, 5 mm, SP Industries
Supplier: SP Industries
Wilmad Precision NMR Quartz Tubes have an extremely low thermal expansion rate and high tensile strength which is 14 times more robust during the cooling/heating process than Type 1 Class A glass tubes.
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Variable-Speed Electric Stirrers, Arrow
Supplier: Arrow Engineering
These variable-speed, electronically controlled stirrers are built to handle viscosities ranging from water-like solutions to highly viscous fluids
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NanoPhotometer® N120-TOUCH UV/Visible Spectrophotometer for 12 Sample Multichannel NanoVolume Applications, Implen
Supplier: IMPLEN, INC. CA
Implen has become the leading expert for innovative, high-quality spectroscopy instruments and the NanoPhotometer® is trusted by thousands of researchers worldwide.
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NanoPhotometer® C40-MOBILE UV/Visible Spectrophotometer for Standard Cuvette Applications, Implen
Supplier: IMPLEN, INC. CA
Implen has become the leading expert for innovative, high-quality spectroscopy instruments and the NanoPhotometer® is trusted by thousands of researchers worldwide.
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NanoPhotometer® N120-MOBILE UV/Visible Spectrophotometer for 12 Sample Multichannel NanoVolume Applications, Implen
Supplier: IMPLEN, INC. CA
Implen has become the leading expert for innovative, high-quality spectroscopy instruments and the NanoPhotometer® is trusted by thousands of researchers worldwide.
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NanoPhotometer® C40-TOUCH UV/Visible Spectrophotometer for Standard Cuvette Applications, Implen
Supplier: IMPLEN, INC. CA
Implen has become the leading expert for innovative, high-quality spectroscopy instruments and the NanoPhotometer® is trusted by thousands of researchers worldwide.
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Semivolatile Calibration Kit #3 (with Benzidine), Restek
Supplier: Restek
Contains 1 ml each of the following mixtures, SV calibration mix #1 (anilines), SV calibration mix #2 (phenols), SV calibration mix #3 (base neutrals), SV calibration mix #4 (base neutrals), SV calibration mix #5 (PAHs), SV calibration mix #7 (dichlorobenzenes) and 605 benzidines calibration mix (benzidine and 3,3'-dichlorobenzidine).
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NanoPhotometer® N60-TOUCH UV/Visible Spectrophotometer for NanoVolume Applications, Implen
Supplier: IMPLEN, INC. CA
Implen has become the leading expert for innovative, high-quality spectroscopy instruments and the NanoPhotometer® is trusted by thousands of researchers worldwide.
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NanoPhotometer® NP80-MOBILE UV/Visible Spectrophotometer for NanoVolume and Standard Cuvette Applications, Implen
Supplier: IMPLEN, INC. CA
Implen has become the leading expert for innovative, high-quality spectroscopy instruments and the NanoPhotometer® is trusted by thousands of researchers worldwide.
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XPert™ Filtered Balance Stations, Labconco®
Supplier: Labconco
These stations provide user protection by keeping powders and particulates contained during weighing procedures
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8270 Calibration Kit, Restek
Supplier: Restek
Contains 1 ml each of the followig mixtures, 8270 calibration mix #1, 8270 calibration mix #2, 8270 calibration mix #3, 8270 calibration mix #4, 8270 calibration mix #5 revised and 3-methylcholanthrene standard.
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VICTOR® Nivo™ Plate Readers, Multi-Mode
Supplier: REVVITY HEALTH SCIENCES CANADA CA
The VICTOR® Nivo™ system packs all popular detection modes into the industry’s smallest multimode reader footprint. The perfect microplate reader for everyday biochemical assays, cell-based assays, molecular biology and immunoassays. Its software interface is easy to learn and use, and lets you control the instrument from almost any device – perfect for multiuser labs. The VICTOR Nivo is a high-performance multimode microplate reader that can be equipped with all major detection technologies: Absorbance, Luminescence, Fluorescence, Time-Resolved Fluorescence, TR-FRET, Fluorescence Polarization, and Alpha Technology.
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NanoPhotometer® NP80-TOUCH UV/Visible Spectrophotometer for NanoVolume and Standard Cuvette Applications, Implen
Supplier: IMPLEN, INC. CA
Implen has become the leading expert for innovative, high-quality spectroscopy instruments and the NanoPhotometer® is trusted by thousands of researchers worldwide.
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CENCO® Mechanics System Kits, 1 and 2
Supplier: VWR International
The CENCO® Mechanics System Kits include activities in mechanics and fluid mechanics topics.
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XPert™ Filtered Balance Systems, Labconco®
Supplier: Labconco
These portable systems provide user protection by keeping powders and particulates contained during weighing procedures
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XPert™ Balance Enclosures, Labconco®
Supplier: Labconco
These low-profile enclosures provide user protection by keeping powders, particulates, and fumes contained during weighing procedures