722 Results for: "1-Aza-15-crown-5 (1,4,7,10-Tetraoxa-13-azacyclopentadecane)"

Supplier: TCI America

CAS Number: 944251-24-5
Molecular Formula: C15H24N4O8
Molecular Weight: 388.38
Form: Clear Liquid
Color: Colorless
Storage Temperature: <0°C

Supplier: Prosci

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Supplier: Proteintech

AMY2B(alpha-amylase 2B) belongs to the glycosyl hydrolase 13 family. This protein is involved in the endohydrolysis of 1,4-alpha-glucosidic linkages in oligosaccharides and polysaccharides. The full length 58 kDa protein has a signal peptide with 15 amino acids. Human amylases (Amy1, Amy2A, and Amy2B) commonly have two potential N-glycosylation sites (N427 and N476) in their C-terminal region (S Takashima, J Amano, 2012).

Supplier: Bioss

Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

Supplier: Bioss

Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

Supplier: DWK Life Sciences (KIMBLE)

Open-top compression cap and connectors consist of glass-filled nylon.

Supplier: Bioss

Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

Supplier: Lauda-Brinkmann

Safe, durable water baths feature an integrated digital controller keypad with an LED that displays the temperature to 0.1°C

Supplier: Argos Technologies

Argos Technologies® PolarSafe™ Metal Freezer Storage Racks are constructed of high-quality, corrosion resistant stainless steel

Supplier: Prosci

Probably involved in the control of the cell cycle. Interacts with D-type G1 cyclins.

Supplier: Chemglass

Adapters permit the connection of standard laboratory dram sample vials directly to the vapor tube or a bump trap of a rotary evaporator.

Supplier: Boster Biological Technology

Polyclonal antibody for 15 LIPOXYGENASE 1/ALOX15 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. 15 LIPOXYGENASE 1/ALOX15 information: Molecular Weight: 74804 MW; Subcellular Localization: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Lipid droplet. Predominantly cytosolic; becomes enriched at membranes upon calcium binding. Translocates from the cytosol to the plasma membrane when stimulated by IL13/interleukin-13 and in macrophages binding apoptotic cells; Tissue Specificity: Detected in monocytes and eosinophils (at protein level). Expressed in airway epithelial cells.

Supplier: VWR

Vials manufactured from 51 expansion borosilicate amber glass conforming to USP Type I, with attached black phenolic caps and PTFE-faced white rubber liners.

Supplier: Glas-Col

The new cartridge design of the Multi Pulse Vortexer allows the user to switch the size of tubes to be mixed by simply changing the cartridge size, thus eliminating the need for extra racks.

Supplier: Prosci

The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Supplier: Bioss

Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

Supplier: Micro Essential

Hydrion Insta-Chek^® pH paper, the ultimate in wide range, general purpose pH papers has a distinct color match at each full pH unit.

Supplier: DWK Life Sciences (KIMBLE)

Amber, screw thread vials with attached black phenolic caps and cone-shaped polyethylene liners.

Supplier: MilliporeSigma

Cas Number 56-86-0, For Synthesis

Supplier: Chemglass

Adapters permit the connection of standard laboratory dram vials directly to the vapor tube or bump trap of a rotary evaporator.

Supplier: TCI America

CAS Number: 5256-79-1
MDL Number: MFCD00308870
Molecular Formula: C48H40O12Si8
Molecular Weight: 1033.52
Form: Crystal
Color: White
Melting point (°C): 500

Supplier: Restek

Contains: Benzene (71-43-2); Bromodichloromethane (75-27-4); Bromoform (75-25-2); Carbon disulfide (75-15-0); Carbon tetrachloride (56-23-5); Chlorobenzene (108-90-7); Chloroform (67-66-3); Cyclohexane (110-82-7); Dibromochloromethane (124-48-1); 1,2-Dibromo-3-chloropropane (DBCP) (96-12-8); 1,2-Dibromoethane (EDB) (106-93-4); 1,2-Dichlorobenzene (95-50-1); 1,3-Dichlorobenzene (541-73-1); 1,4-Dichlorobenzene (106-46-7); 1,1-Dichloroethane (75-34-3); 1,2-Dichloroethane (107-06-2); 1,1-Dichloroethene (75-35-4); cis-1,2-Dichloroethene (156-59-2); trans-1,2-Dichloroethene (156-60-5); 1,2-Dichloropropane (78-87-5); cis-1,3-Dichloropropene (10061-01-5); trans-1,3-Dichloropropene (10061-02-6); Ethylbenzene (100-41-4); Isopropylbenzene (cumene) (98-82-8); Methyl acetate (79-20-9); Methyl tert-butyl ether (MTBE) (1634-04-4); Methylcyclohexane (108-87-2); Methylene chloride (dichloromethane) (75-09-2); Styrene (100-42-5); 1,1,2,2-Tetrachloroethane (79-34-5); Tetrachloroethene (127-18-4); Toluene (108-88-3); 1,2,4-Trichlorobenzene (120-82-1); 1,1,1-Trichloroethane (71-55-6); 1,1,2-Trichloroethane (79-00-5); Trichloroethene (79-01-6); 1,1,2-Trichloro-1,2,2-trifluoroethane (CFC-113) (76-13-1); m-Xylene (108-38-3); o-Xylene (95-47-6); p-Xylene (106-42-3).

Supplier: DWK Life Sciences (KIMBLE)

These sample vials have closed top black phenolic closure with white rubber liners, attached.

Supplier: Prosci

IL-15 Antibody: Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.

Supplier: Prosci

Caspase-13 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.

Supplier: Thermo Scientific

These storage screw thread vials are manufactured from superior quality 33 expansion borosilicate clear Type 1, Class A or 51A amber Type 1, Class B glass.

Supplier: DWK Life Sciences (KIMBLE)

Screw thread sample vials with attached closures manufactured from clear 33 expansion borosilicate glass.

Supplier: Restek

Contains: Chain, Compound (CAS#), % by Weight; C16:00 Methyl palmitate (112-39-0), 3%; C16:01 Methyl palmitoleate (1120-25-8), 1%; C18:00 Methyl stearate (112-61-8), 2%; C18:01 Methyl oleate (112-62-9), 20%; C18:02 Methyl linoleate (112-63-0), 15%; C18:03 Methyl linolenate (301-00-8), 10%; C20:00 Methyl arachidate (1120-28-1), 1%; C20:01 Methyl eicosenoate (20839-34-3), 10%; C20:02 Methyl eicosadienoate (2463-02-7), 2%; C22:00 Methyl behenate (929-77-1), 1%; C22:01 Methyl erucate (1120-34-9), 30%; C22:02 Methyl docosadienoate (61012-47-3), 2%; C24:00:00 Methyl lignocerate (2442-49-1), 1%; C24:01:00 Methyl nervonate (2733-88-2), 2%

Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA

Vials with 2 ml wide opening are constructed from type 33 and type 51 COE borosilicate glass, with low metal content, to protect your sample from destabilizing or leaching.

Supplier: TCI America

CAS Number: 635-46-1
MDL Number: MFCD00006693
Molecular Formula: C9H11N
Molecular Weight: 133.19
Purity/Analysis Method: >95.0% (GC)
Form: Clear Liquid
Color: Colorless
Boiling point (°C): 251
Flash Point (°C): 113
Freezing point (°C): 13
Specific Gravity (20/20): 1.06
Storage Temperature: 0-10°C