"1,6-diaminopurine"

Supplier: Fujifilm Irvine Scientific

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

Supplier: Thermo Scientific Chemicals

1-Hexyl-3-methylimidazolium trifluoromethanesulfonate 95%

Supplier: Prosci

TMEM135 Antibody: The transmembrane protein 135 (TMEM135), also known as peroxisomal membrane protein 52 (PMP52), was initially identified as a protein that might be critical for adipogenesis and osteoblastogenesis. Further studies have indicated that TMEM135 may be part of a regulatory circuit that plays an important role in fat metabolism and energy expenditure in both C. elegans as well as mammalian organisms. Finally, recent experiments has suggested that TMEM135 may be an additional driver of breast cancer.

Supplier: Eppendorf

Various adapters, rotors, and other accessories for centrifuges 5804 and/or 5804R and/or 5810 and/or 5810R. Eppendorf Rotors for Centrifuges 5804(R) and 5810(R) precision meets power. Customize your centrifugation with varied capacities and speeds. Accessorize with versatile buckets and adaptors for efficient sample processing. Ideal for high-performance applications, ensuring accuracy and reproducibility.

Supplier: TCI America

CAS Number: 75460-28-5
MDL Number: MFCD00143200
Molecular Formula: C16H23BrO6
Molecular Weight: 391.26
Purity/Analysis Method: >95.0% (GC)
Form: Crystal
Melting point (°C): 80

Supplier: LGC Standards

TRC (S)-(+)-Methoprene

Supplier: Prosci

BMP15 Antibody: BMP15, or GDF9B is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily that are involved in embryonic development and adult tissue homeostasis. BMP15 is expressed exclusively in the oocyte. It is an oocyte-specific growth/differentiation factor that may be involved in oocyte maturation and follicular development. Defects in BMP15 are the cause of ovarian dysgenesis type 2. BMP15 could be used as an oogenesis marker to track human amniotic fluid stem cells differentiation into the oocyte-like cells.

Supplier: Prosci

RIM2 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. RIM1 and RIM2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release; synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like RIM1, RIM2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.

Supplier: Prosci

OCC-1 Antibody: OCC-1 (Overexpressed in colon carcinoma-1) was initially identified as a novel human cDNA overexpressed in a colon carcinoma cell line. Elevated levels of OCC-1 mRNA were observed in three of eight colon carcinomas, suggesting that OCC-1 may be a hallmark of only a subset of colon carcinomas. It is highly expressed in skeletal muscle, kidney, placenta, and pancreas tissues, with low to no expression in heart, brain, lung and liver tissues. At least two different OCC-1 mRNA species are known to exist.

Supplier: Prosci

TLX1 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.

Supplier: Prosci

UBD, also designated ubiquitin D or diubiquitin, plays a role in antigen presentation, cytokine response and apoptosis. It is a 165 amino acid protein encoded in the major histocompatibility complex (MHC) that consists of two domains which share significant homology with ubiquitin. UBD is inducible by interferon gamma and TNF-alpha and regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. It may also regulate cell growth during dendritic cell or B cell activation and development.

Supplier: Thermo Scientific Chemicals

Benzofuran-2-carboxaldehyde 99%

Supplier: Thermo Scientific Chemicals

4-[(Trifluoromethyl)thio]aniline 98%

Supplier: LGC Standards

CDN Isotopes Diphenhydramine-d5 HCl (phenyl-d5)

Supplier: TCI America

Cesium(I) bis(trifluoromethanesulfonyl)imide ≥98.0% (by titrimetric analysis)

Supplier: LGC Standards

TRC Dolutegravir