12523 Results for: "1,4-butane14diylbis(3-aminocrotonate)"
Corrected to: 1,4-but2yne14diylbis(3-aminocrotonate)
Anti-PI14 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Supplier: Bioss
SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
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Anti-PI14 Rabbit Polyclonal Antibody (Cy3®)
Supplier: Bioss
SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
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Anti-MCP1 Mouse Monoclonal Antibody [clone: S14]
Supplier: Genetex
This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
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Anti-MAPK14 Rabbit Polyclonal Antibody
Supplier: Prosci
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
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Human Recombinant Hvem-Fc (from Hi-5 Insect cells)
Supplier: Prosci
HVEM belongs to the TNF Receptor superfamily of transmembrane proteins and plays a role in the activation of T-cells and other lymphocytes. It is expressed in various cells and tissues including spleen, thymus, lung, macrophages, and T-cells. HVEM activation induces a signaling cascade which results in induction of transcription factors NF-kappaB and AP-1. LIGHT (TNFSF14) and TNF-beta (TNFSF1) function as the ligands for HVEM, which can also bind specifically to herpes simplex virus glycoprotein D. Soluble HVEM can act as a "receptor decoy” resulting in inhibition of the activity of the HVEM ligands, LIGHT and TNF-beta. Recombinant human HVEM-Fc Chimera is a 376 amino acid fusion protein containing an N-terminal domain corresponding to the extracellular region of HVEM and a C-terminal domain corresponding to residues 102 to 330 of human IgG1.
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Anti-MAPK14 Rabbit Polyclonal Antibody
Supplier: Prosci
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
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SingleQuots® hMSC Human Mesenchymal Stem Cell Chondrogenic Differentiation Kit
Supplier: LONZA PHARMA - BIOSCIENCE CA
Stem cells possess the unique ability to differentiate into multiple lineages of cells including chondrocytes.
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Anti-PI14 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Supplier: Bioss
SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
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Anti-GALNT14 Rabbit Polyclonal Antibody
Supplier: Prosci
GALNT14 (EC 2.4.1.41) belongs to a large subfamily of glycosyltransferases residing in the Golgi apparatus. GALNT enzymes catalyze the first step in the O-glycosylation of mammalian proteins by transferring N-acetyl-D-galactosamine (GalNAc) to peptide substrates. GALNT14 (EC 2.4.1.41) belongs to a large subfamily of glycosyltransferases residing in the Golgi apparatus. GALNT enzymes catalyze the first step in the O-glycosylation of mammalian proteins by transferring N-acetyl-D-galactosamine (GalNAc) to peptide substrates.
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Anti-CXCL14 Rabbit Polyclonal Antibody
Supplier: Prosci
CXCL14 belongs to the cytokine family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.
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Anti-MAPK14 Rabbit Polyclonal Antibody
Supplier: Prosci
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
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Anti-PHF14 Rabbit Polyclonal Antibody
Supplier: Prosci
PHF14, a novel plant homology domain (PHD) transcription factor, controls the proliferation of mesenchymal cells by regulating PDGFR alpha expression in embryonic development. PHD finger transcription factors are concerned with transcriptional regulation by interacting with modified histones (2), and dysregulation of several genes encoding PHD finger transcription factors, such as ING1 and RBP2, has been found in human cancer diseases suggesting these factors have an important role for cancer cell proliferation. PHF14 is a potential target for new treatments of lung fibrosis (1, 3).
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NPS® Height Adjustable Heavy Duty Vinyl Padded Swivel Steel Stool With Backrest, National Public Seating
Supplier: National Public Seating
High-quality Height Adjustable Heavy Duty Vinyl Padded Swivel Steel Stool With Backrest is a great value.
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Cole-Parmer® HG-600 Geno/Grinder® 2010 Tissue Homogenizers and Cell Lysers
Supplier: SPEX
The Geno/Grinder® is an automated high-throughput plant and animal tissue homogenizer and cell lyser.
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SP Bel-Art Touch Free™ Automatic Waste Cans, Bel-Art Products, a part of SP
Supplier: Bel-Art Products, a Part of SP
The Touch Free™ Automatic Waste Can’s motion-sensitive lid opens automatically to accept waste, and then closes into a fitted well that helps to reduce odor and airborne contamination.
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TRU-STIR Stirrer Shaft Couplings, Compact 3" Long, Chemglass
Supplier: Chemglass
The unique design of our Tru-Stir™ stirrer shaft coupling eliminates the need to use rubber hose or universal adapters to attach your stirrer shafts to overhead stir motors. Coupling incorporates a unique helical S.S. spring permitting up to ¹/₈" of offset misalignment. Coupling is rated for 21 in-lbs of torque without the backlash normally associated with common coil springs.
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VWR® Disposable Spatulas, PP
Supplier: VWR International
Economical, disposable tools for transferring, collecting, and handling chemical and biological materials.
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VWR® Advanced 5000 Orbital Shakers, 230 V (Export Only)
Supplier: VWR International
Digital orbital shakers are designed for a wide range of applications including solubility studies, extraction procedures, and cell cultures that require accurate and reproducible results.
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Anti-ST14 Rabbit Polyclonal Antibody
Supplier: Prosci
ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
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Masterflex® Ismatec® Reglo Digital Multichannel Pumps, Avantor®
Supplier: Avantor Fluid Handling
Versatile multichannel pumps for accurate low-flow fluid delivery – with an intuitive touch-screen interface.
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VWR® Advanced 15000 Orbital Shakers, 230 V
Supplier: VWR International
Digital orbital shakers are designed for a wide range of applications such as solubility studies, extraction procedures, and cell cultures that require accurate and reproducible results.
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VWR® Advanced 10000 Orbital Shakers
Supplier: VWR International
Digital orbital shakers are designed for a wide range of applications including solubility studies, extraction procedures, and cell cultures that require accurate and reproducible results.
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VWR® Advanced 3750 Reciprocating Shakers
Supplier: VWR International
Digital reciprocating shakers are designed for a wide range of applications including solubility studies, extraction procedures, and cell cultures that require accurate and reproducible results.
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Anti-TNFRSF14 Rabbit Polyclonal Antibody
Supplier: Prosci
TNFRSF14 Antibody: Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-kappa B and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.
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Anti-CARD14 Rabbit Polyclonal Antibody (Cy5.5®)
Supplier: Bioss
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
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Anti-MAP3K14 Rabbit Polyclonal Antibody
Supplier: Prosci
NIK Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha , LPS and mitogens. A serine/threonine protein kinase which mediates NF-kappa B activation by IL-1, TNFalpha and CD95 was identified recently and designated NIK (for NF-kappa B inducing kinase). NIK is an activator of Ikappa B kinase alpha and beta (IKKalpha and IKKbeta ;). Therefore, NIK is a key molecule in the NF-kappa B signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.
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Cubis® II Premium High Capacity Laboratory Balances, Sartorius
Supplier: Sartorius
These Cubis® II premium high capacity laboratory balances are ideal for high-performance portfolio of both labs weighing hardware and software.
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Hardness (Total), Titrets Titration Cells, CHEMetrics
Supplier: Chemetrics
The test kits utilize CHEMetrics Titrets® ampoules. Titrets ampoules use a reverse titration technique to measure analyte concentration levels (titrant volume inside the ampoule is fixed while the sample volume is varied).
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Celestron EclipSmart Solar Filter for PS 127EQ/SSE DX 130/130SLT
Supplier: Celestron International
Turn a Celestron telescope into a solar scope.
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Axygen® Gel Documentation Systems, Corning
Supplier: Corning
Axygen® gel documentation systems easily capture publication quality, 16 bit TIFF images. The systems are quick to set up and have an intuitive user interface for image capture, annotation, and contrast adjustment. Images are easily saved and opened in common gel analysis software for more detailed analysis.