19811 Results for: "1,2-Bis(phenylsulfonyl)ethane"
Blue Sepharose™ 6 Fast Flow Affinity Chromatography Media, Cytiva
Supplier: Cytiva
Blue Sepharose™ 6 Fast Flow is cibacron blue 3G coupled to Sepharose™ 6 Fast Flow. It is well established as an adsorbent for albumin and interferon at both laboratory and process scale. The blue dye binds many proteins, such as albumin, interferon, lipoproteins and blood coagulation factors. It also binds several enzymes including kinases, dehydrogenases, and most enzymes requiring adenyl-containing cofactors e.g. NAD+.
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Long-Handled Scraper With Safety Blade, Slice®
Supplier: SLICE, INC.
The Slice® Long-Handled Scraper extends your reach with a sturdy aluminum handle. This scraper has a weight that’s balanced to feel solid without being too heavy to use comfortably.
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Anti-COLEC12 Rabbit Polyclonal Antibody
Supplier: Prosci
COLEC12 is a member of the C-lectin family,¡¡proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.
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FOCUS: SAFETY - OUT NOW!
Let’s enhance safety by considering personalized protection equipment (PPE) solutions tailored to your team, processes, and products.
Anti-MGAT2 Rabbit Polyclonal Antibody
Supplier: Prosci
MGAT2 is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in its gene may lead to carbohydrate-deficient glycoprotein syndrome, type II.The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. Two transcript variants encoding the same protein have been identified for this gene.
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Ultra-Low Temperature Freezers, TSX Universal -86 °C ULT
Supplier: Thermo Fisher Scientific
TSX Universal series ULT freezers are the pinnacle of reliability, sustainability, and innovation incorporating insights from over 80 years of experience to enhance every aspect of the system. Updates to the variable speed compressors has made the TSX Universal adaptable across all workflows. Available in four capacities, they are ENERGY STAR® certified with a 33% energy efficiency improvement, ACT labeled and produced in a Zero-Waste to Landfill certified facility.
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XPert™ Filtered Balance Stations, Labconco®
Supplier: Labconco
These stations provide user protection by keeping powders and particulates contained during weighing procedures
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Socorex™ Acura® electro Variable Volume Pipettes, DWK Life Sciences
Supplier: DWK Life Sciences (KIMBLE)
The Acura® electro pipettes are the latest upgrade of a successful line that makes electronic pipetting more versatile, simpler, and safer than ever.
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Anti-ADAM12 Rabbit Polyclonal Antibody
Supplier: Proteintech
ADAM12, also named as MLTN and Meltrin-alpha, is involved in skeletal muscle regeneration, specifically at the onset of cell fusion. It is also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. ADAM12 is expressed in human malignant tumors. It is involved in the regulation of growth factor activities and integrin functions, leading to promotion of cell growth and invasion, although the precise mechanisms of these are not clear at the present time. ADAM12’s ability to degrade extracellular matrix components likely allows it to detach cancer cells from the basement membrane and assist them on their route to metastasis. But the protein’s role not just as a biomarker of breast cancer but as a gateway to cancer cell migration is only now being understood. This antibody can recognize all isoforms of ADAM12. ADAM12 has 4 forms: 120kd full-length form, 90kd mature(processed form that lack the prodomain);50-68kd degradation product and 27kd prodomain.
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AiroSensor Temperature Sensor, with Module for Open Door Monitoring in Refrigerators and Freezers
Supplier: SENSEANYWHERE BV
The SenseAnywhere AiroSensor 20-20-41 with Magnetic Door Contact Set is the ultimate solution to your refrigeration and freezer challenges. We all know the frustration of discovering that your fridge or freezer has failed due to an open door. With this efficient duo, you can say goodbye to this common problem.
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PRP-h1 Polymeric Reversed Phase HPLC Columns, Hamilton Company
Supplier: Hamilton
Hamilton Company offers one of the most comprehensive selections of chromatography columns in the industry.
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MaxQ™ 8000 Stackable Orbital Shakers, 240 V
Supplier: Thermo Fisher Scientific
Stackable orbital shakers provide an ideal solution for both sensitive cultures and traditional 'hard shake' applications in incubated and refrigerated configurations.
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General Purpose Unstirred Digital Water Bath Range, Grant Instruments
Supplier: GRANT USA INC.
General Purpose Water Baths with stable temperature control, simple interface and fast heat-up. Choose from four models each with base tray and lid included as standard.
The JB Nova general purpose unstirred water bath range benefits from key features such as the newly incorporated Set and Forget™ technology with advanced dry start and run dry protection. These are in addition to the standard features including an element free tank, user calibration, front panel lock and drain tap on sizes 12L and above
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TSX Series Ultra-Low Temperature Freezers, Thermo Scientific
Supplier: Thermo Fisher Scientific
Thermo Scientific™ TSX Series ultra-low freezers are designed to meet the highest standards for –80 °C and –70 °C storage in reliability, sustainability and temperature management.
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FilterMax™ F3 and F5 Multimode Microplate Readers, Molecular Devices
Supplier: MOLECULAR DEVICES LLC. CA
The FilterMax™ F3 features absorbance (visible), fluorescence intensity - FI (top reading), and glow luminescence for 96- to 384-well plates.
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Advanced Spectroscopy Lab System
Supplier: SPECTRUM TECHNIQUES, LLC
The ADVANCED Spectrometer System is capable for conducting a wide selection of spectroscopy experiments.
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Heidolph® Peristaltic Pump Systems, Hei-FLOW Ultimate
Supplier: Heidolph NA, LLC
Pump drives are suitable for use with applications requiring the highest standards involving corrosive solvents or sterilized media
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Pierce™ PNPP Substrates, Thermo Scientific
Supplier: Thermo Scientific
Thermo Scientific™ Pierce PNPP Substrates are powders, tablets, solutions and complete kits of p-nitrophenyl phosphate, a colorimetric, soluble substrate of alkaline phosphatase for use in ELISA applications
PNPP (p-Nitrophenyl Phosphate, Disodium Sal) is a widely used substrate for detecting alkaline phosphatase in ELISA applications. When alkaline phosphatase and PNPP are reacted, a yellow water-soluble reaction product is formed. This reaction product absorbs light at 405 nm. Pierce PNPP is available in four formats: dry crystalline powder, single-use tablets, a stable substrate solution, and a complete kit containing substrate solution and diethanolamine buffer.
Thermo Scientific Pierce PNPP (p-Nitrophenyl Phosphate, Disodium Salt) is a colorimetric, soluble substrate of alkaline phosphatase for use in ELISA applications. When alkaline phosphatase and PNPP are reacted, a yellow water-soluble reaction product is formed. This reaction product absorbs light at 405 nm.
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Vortex Genie® Mixers, 230/240 V, Scientific Industries
Supplier: Scientific Industries
Vortex Genie® Mixers are available in multiple models and with a vast array of available platforms and accessories.
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Anti-F12 Rabbit Polyclonal Antibody (Cy5.5®)
Supplier: Bioss
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].
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Heidolph® Peristaltic Pump Systems, Hei-FLOW Expert
Supplier: Heidolph NA, LLC
Pump drives are ideal for all standard applications involving corrosive solvents or sterilized media
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Anti-KLF12 Rabbit Polyclonal Antibody
Supplier: Prosci
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1.Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
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GsBP®-5 Non-Polar GC Columns, GS-Tek
Supplier: General Separation Technologies, Inc.
Amines & Phenols, Amphetamines and Precursors - TMS Derivative, Antihistamines, Aroclors 1016-1268 (without 1221), Bacterial Fatty Acid Methyl Esters, Basic Drugs (Underivatized), Benzodiazepines (Basic Drugs - Underivatized), Bergamot Oil, Butter Triglycerides, Cannabinoids (TMS Derivatives), Chlorinated hydrocarbons, CLP Pesticides, Cocaine & Metabolites (TMS Derivatives), Cold Medication, Cold-Pressed Orange Oil, Common Drug Screen, Congeners in DIN Method PCBs, Ethanolamines, Typical Application: Ethyleneamines, European Red List Volatiles, Garlic Oil, Herbicides, Lemon Oil, Marijuana - TMS Derivatives, Major Metabolites - TMS Derivatives, Motor Oil, Narcotics and Adulterants, Opiates (TMS Derivatives), Organic Volatile Impurities, Organochlorine Pesticides, Organomercury Compounds, Organotin Compounds II, Pain Killers - TMS Derivatives, PBDEs, PCBs by EPA Method 8083, Phencyclidine (PCP), Phytosterols (Saw Palmetto), Steroids: Anabolic (Underivatized), Sympathomimetic Amines Derivatives, Ylang Ylang Oil.
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Anti-TCF12 Rabbit Polyclonal Antibody
Supplier: Prosci
TCF12 encodes a protein that is a member of the basic helix-loop-helix (bHLH) E-protein family which recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins.The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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PIG® Grippy® Adhesive-Backed Floor Mats, New Pig
Supplier: New Pig
Hassling with rubber-backed floor mats or rental mats? Make the switch to the mat that sticks — our super-safe, adhesive-backed commercial absorbent runner. Perfect for grocery and retail environments.
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Anti-CDK12 Rabbit Polyclonal Antibody
Supplier: Thermo Scientific
This antibody is predicted to react with rat based on sequence homology. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
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Anti-SNAP25 Mouse Monoclonal Antibody [clone: 3E4B7]
Supplier: Proteintech
The synaptosomal associated protein of 25 kD (SNAP-25) was first identified as a major synaptic protein by Wilson and colleagues. The protein interacts with syntaxin and synaptobrevin through its N-terminal and C-terminal -helical domains. Its palmitoylation domain is located in the middle of the molecule that contains four cysteine residues. Mutation of the cysteines abolishes palmitoylation and membrane binding. Several elegant studies using synaptosome preparations and permeabilized PC12 cells have suggested that SNAP-25 may act in the late post-docking steps of exocytosis. By limited proteolysis and in vitro binding assay, it is proposed that the two helix domains act independently and contribute equally to form the SNARE complex with syntaxin and synaptobrevin. It seems that a major regulatory element is located in the C-terminus of SNAP-25. Removing a 9 amino acid sequence of SNAP-25 inhibited neurosecretion in chromaffin cells. In addition, it has been shown that inhibition of neurosecretion by botulinum toxin E can be rescued by a SNAP-25 C-terminal peptide, probably by initiating the formation of a fusion competent SNARE complex.
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Anti-F12 Rabbit Polyclonal Antibody
Supplier: Bioss
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].
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Protector® ClassMate™ Laboratory Hoods, Labconco®
Supplier: Labconco
ClassMate™ laboratory hoods are designed to meet the needs of instructional laboratories.
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Heracell VIOS 250i CO₂ Incubators, Thermo Scientific
Supplier: Thermo Fisher Scientific
Designed to achieve your next breakthrough. Better solutions for optimal cell growth, VIOS CO₂ incubators provide the ideal in-vitro environment.
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Cubis® II Essential Premium Precision Balances, Manual Leveling, Sartorius
Supplier: Sartorius
These MCE series essential user interface balance was a large, high-contrast touch display with factory-installed essential weighing applications for easy operation.