19811 Results for: "1,2-Bis(phenylsulfonyl)ethane"

Supplier: Greiner Bio-One

The VACUETTE® Safety Blood Collection Set with Blood Culture Holder is used in routine venipuncture procedures.

Supplier: Bioss

May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.

Supplier: Bioss

May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.

Supplier: VWR International

Hi/Lo Alarms and Time/Date Stamps: Unique alarm settings can be programmed for both humidity and temperature parameters

Supplier: Cytiva

Ni Sepharose™ excel is an IMAC medium pre-charged with nickel ions very strongly bound to a chelating ligand. Samples that usually cause stripping of metal ions can, therefore, be loaded to the medium. Ni Sepharose™ excel is designed primarily for capture and purification of histidine-tagged proteins secreted into cell culture supernatants from eukaryotic cells such as insect cells or CHO cells.

Supplier: Thermo Fisher Scientific

Our CryoPlus LN2 storage systems provide precise and accurate control over all parameters without complicated programming.

Supplier: Cytiva

Capto MMC is a multimodal cation exchanger with a different selectivity, compared with traditional ion exchangers.

Supplier: Prosci

TWEAK Antibody: TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.

Supplier: Biotium

Calgranulin B / MRP-8/-14 / MAC 387Monoclonal antibody, Clone: MAC387, Host: Mouse, Species reactivity: Monkey, Goat, Baboon, Pig, Dog, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recognizes L1 molecule, 12kDa alpha/14kDa beta chain, Size: 100ul

Supplier: Biotium

Calgranulin B Monoclonal antibody, Clone: MAC387, Host: Mouse, Species: Monkey, Goat, Baboon, Pig, Dog, Isotype: IgG1, K, Conjugate: CF647, Immunogen: Recognizes the L1 or Calprotectin molecule of a 12kDa and 14kDa, Synonyms: MRP-8/-14, Application: IF, IHC, Fc, Size: 500ul

Supplier: Prosci

PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain; the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.

Supplier: Cytiva

The illustra™ triplePrep Kit is designed for the rapid, simultaneous extraction and isolation of high yield genomic DNA (gDNA), total RNA, and total denatured proteins from undivided animal tissues and mammalian cells. The streamlined workflow reduces the overall number of steps, enabling the preparation of all three analytes in less than one hour.

Supplier: Labconco

Enclosures provide a controlled environment in which to perform polymerase chain reaction (PCR) procedures

Supplier: VWR International

This thermometer’s recorder output jack provides a 1mV signal per degree, which enables it to be used with any chart recorder, strip recorder, or computer that accepts millivolt signals.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Achieve control over laboratory variables -- minimizing variability and maximizing consistency of results -- by relying on salts in a variety of grades - ACS, BAKER, etc. The USP/NF Offical Compendia of Standards contains a section titled, "Reagents, Indicators, and Solutions" that lists the quality requirements of chemicals to be used in compendia testing. PharmaTest reagents are tested according to these requirements, relieving you of the need to do additional testing on your reagents. Products may be reagent or other grade, but are labeled as "Meets reagent specifications for testing USP/NF monographs." Test solutions are labeled as PharmaTest.

Supplier: VWR International

Versatile pumps for accurate fluid delivery – with an intuitive touch-screen interface.

Supplier: VWR International

Easily access collected data between destinations with Bluetooth® data loggers.

Supplier: Prosci

TIGAR Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death; loss of its functions contributes to the development of most cancers. Recent studies have demonstrated the ability of p53 to regulate the expression of several proteins involved in glycolysis and oxidative phosphorylation, such as TIGAR, SCO2, and phosphoglycerate mutase. TIGAR is a recently discovered protein that functions to regulate glycolysis and protect cells against oxidative stress. TIGAR is similar in structure to proteins in the phosphoglycerate mutase family, most notably 6-phosphofructo-2-kinase, suggesting TIGAR may function as a fructose bisphosphatase. Expression of TIGAR in transfected cells correlated with an inhibition of glycolysis and decreased levels of reactive oxygen species and p53-induced apoptosis, indicating that TIGAR may act to modulate the apoptotic response to p53, thereby allowing cells to survive mild or transient stresses.

Supplier: Cytiva

Capto™ adhere ImpRes is a strong anion exchange multimodal BioProcess chromatography medium (resin), designed to meet the demands of modern large-scale manufacturers, for high-resolution polishing of monoclonal antibodies (MAbs) and other biomolecules. Capto™ adhere ImpRes is designed to allow effective MAb polishing in the second or third step of a purification scheme downstream of the protein A capture step. Polishing can be performed in either bind and elute (binding) or flowthrough (non binding) modes.

Supplier: Prosci

ATG101 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG101 is a recently discovered protein that stabilizes ATG13, another autophagy protein that forms a complex with the mammalian homologs of ATG1, ULK1 and ULK2, and with FIP200. This complex is a target of TOR phosphorylation under normal conditions; inhibition of TOR by rapamycin or leucine deprivation leads to dephosphorylation of ATG13, ULK1 and ULK2, which then leads to autophagy. ATG101 also interacts with ULK1 and is essential for autophagy.

Supplier: Biotium

Calgranulin B / MRP-8/-14 Monoclonal antibody, Clone: MAC387, Host: Mouse, Species reactivity: Monkey, Goat, Baboon, Pig, Dog, Cow, Cat, Rat, Human, Isotype: IgG1, K, Conjugate: CF568, Synonyms: MAC 387 / S100A8/A9 / Macrophage Ag, Size: 500 uL

Supplier: Justrite

This Single Cylinder Hand Truck with Hoist Ring provides safety when moving and storing of gas cylinders.

Supplier: Huber

Refrigeration bath circulators are suitable for controlling the temperature of externally connected applications and thermoregulation of objects directly in the thermostat bath

Supplier: Bioss

May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-kB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.

Supplier: Biotium

Calgranulin B / MRP-8/-14 Monoclonal antibody, Clone: MAC387, Host: Mouse, Species reactivity: Monkey, Goat, Baboon, Pig, Dog, Cow, Cat, Rat, Human, Isotype: IgG1, K, Conjugate: CF488A, Synonyms: MAC 387 / S100A8/A9 / Macrophage Ag, Size: 500 uL

Supplier: Greiner Bio-One

Leucosep™ tubes have been developed for the optimal separation of lymphocytes and peripheral mononuclear cells from human whole blood and bone marrow by means of density gradient centrifugation.

Supplier: Prosci

ACADM Is the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Clinical phenotypes are associated with ACADM hereditary deficiency.This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Supplier: Thermo Fisher Scientific

The Barnstead GenPure Pro water purification systems provide up to 200L/day of Type 1, ultrapure (18.2 megohm) water from pre-treated feed water

Supplier: Prosci

ATG101 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG101 is a recently discovered protein that stabilizes ATG13, another autophagy protein that forms a complex with the mammalian homologs of ATG1, ULK1 and ULK2, and with FIP200. This complex is a target of TOR phosphorylation under normal conditions; inhibition of TOR by rapamycin or leucine deprivation leads to dephosphorylation of ATG13, ULK1 and ULK2, which then leads to autophagy. ATG101 also interacts with ULK1 and is essential for autophagy.

Supplier: ROEMER INDUSTRIES, INC.

PharmaRoam3 is a medical-grade, countertop refrigerator or freezer that has optional accessories such as battery power and data management. Designed to transport vaccines and pharmaceuticals, units function as refrigerators or freezers down to 1 °C (optional −20 °C with refrigerant change) and run on a battery while on the move. These units can be secured with a padlock, have a handle on the top and can be stacked with stacking corners. Excellent for disaster preparedness to store temperature sensitive products when the electrical power supply is not reliable or dependable.