240 Results for: "1,2,3,4-tetraphenylcyclopentadienone"

Supplier: Genetex

Binding of scatter factor (SF)/hepatocyte growth factor (HGF) to the c Met receptor tyrosine kinase (RTK) triggers receptor dimerization and phosphorylation on multiple residues within the juxtamembrane, catalytic core and cytoplasmic tail domains, thereby regulating receptor internalization, catalytic activity and multisubstrate docking. c Met contains three tyrosines (Tyrx- x-x-Tyr-Tyr motif) within the activation loop of the catalytic domain, for which phosphorylation of all three (tyrosines 1230, 1234, and 1235) is required for full activation. Activation of the c Met/HGF receptor results in binding and/or phosphorylation of many intracellular signaling proteins including multiple adaptor proteins (e.g., Grb2, Shc, Cbl, Crk, cortactin, paxillin, and GAB1), and a variety of other signal transducers (e.g., PI 3-kinase, FAK, Src, ERK1&2, JNK1&2, PLC gamma, and STAT3). Tyr1349 of c Met is one of the primary docking sites for PI 3-kinase and GAB1. The phosphorylation of tyrosines 1349 and 1356 serves as a priming mechanism for protein binding.

Supplier: Spectrum Chemicals

Xylitol, FCC is used as nutritive sweetener as a sugar substitute to produce “sugar-free” foods and is commonly used in the production of chewing gums, mints and other candies. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage, nutritional supplements and personal care applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Supplier: Thermo Scientific Chemicals

D-(+)-Arabitol 99%

Supplier: Thermo Scientific Chemicals

Pentamethylbenzene 99%

Supplier: Thermo Scientific Chemicals

Xylitol 99%

Supplier: Thermo Scientific Chemicals

Inhibitor of protein kinase A

Supplier: Enzo Life Sciences

Key reagent for generating luminescence

Supplier: Thermo Scientific Chemicals

5-(3-Chlorophenyl)-1H-tetrazole 98+%

Supplier: Thermo Scientific Chemicals

5-Hydroxy-1-tetralone 99%

Supplier: Thermo Scientific Chemicals

Supplier: Spectrum Chemicals

XYLITOL, NF is a naturally occurring 5-carbon sugar alcohol found in many fruits and vegetables. Xylitol is used as nutritive sweetener as a sugar substitute to produce “sugar-free” foods and is commonly used in the production of chewing gums, mints and other candies. It is healthier than sugar (75% fewer carbohydrates and 40% fewer calories) and just as sweet. Is often used in tooth care products and has proven to be healthier for teeth than sugar. Although its main use is as a food additive, it is also used medicinally to prevent middle ear infections in young children. The NF grade indicates it is graded suitable for personal care, cosmetic and pharmaceutical applications. All Spectrum Chemical NF grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Supplier: Prosci

eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. Interacts with eIF3, mutually exclusive with EIF4A1 or EIFA2, EIF4E and through its N-terminus with PAPBC1. Interacts through its C-terminus with the serine/threonine kinases MKNK1, and with MKNK2. Appears to act as a scaffold protein, holding these enzymes in place to phosphorylate EIF4E. Non-phosphorylated EIF4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E; insulin stimulated MAP-kinase (MAPK1 and MAPK3) phosphorylation of EIF4EBP1 causes dissociation of the complex allowing EIF4G1/EIF4G3 to bind and consequent initiation of translation. EIF4G1/EIF4G3 interacts with PABPC1 to bring about circularization of the mRNA. Rapamycin can attenuate insulin stimulation mediated by FKBPs. Interacts with EIF4E3. Interacts with MIF4GD. Interacts with rotavirus A NSP3; in this interaction, NSP3 takes the place of PABPC1 thereby inducing shutoff of host protein synthesis

Supplier: Thermo Scientific Chemicals

Powder, packaged under argon

Supplier: Thermo Scientific Chemicals

Angiotensin-converting enzyme inhibitor

Supplier: Thermo Scientific Chemicals

Potent, selective kainate/quisqualate (non-NMDA) receptor antagonist

Supplier: TCI America

CAS Number: 6836-19-7
MDL Number: MFCD00001696
Molecular Formula: C11H12O2
Molecular Weight: 176.22
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 62

Supplier: TCI America

CAS Number: 3470-50-6
MDL Number: MFCD00156670
Molecular Formula: C10H10O2
Molecular Weight: 162.19
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 155

Supplier: TCI America

CAS Number: 33892-75-0
MDL Number: MFCD00001692
Molecular Formula: C11H12O2
Molecular Weight: 176.22
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 162
Melting point (°C): 90

Supplier: TCI America

CAS Number: 32940-15-1
MDL Number: MFCD00064958
Molecular Formula: C11H12O2
Molecular Weight: 176.22
Purity/Analysis Method: >95.0% (GC)
Form: Crystal
Boiling point (°C): 165
Melting point (°C): 37

Supplier: TCI America

CAS Number: 2472-22-2
MDL Number: MFCD00001729
Molecular Formula: C11H12O2
Molecular Weight: 176.22
Purity/Analysis Method: >95.0% (GC)
Form: Crystal
Flash Point (°C): 110
Freezing point (°C): 28
Storage Temperature: 0-10°C

Supplier: TCI America

[Chemiluminescence reagent]
CAS Number: 3682-14-2
MDL Number: MFCD00010560
Molecular Formula: C8H7N3O2
Molecular Weight: 177.16
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 300

Supplier: TCI America

[Chemiluminescence Reagent]
CAS Number: 521-31-3
MDL Number: MFCD00006890
Molecular Formula: C8H7N3O2
Molecular Weight: 177.16
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 320

Supplier: Enzo Life Sciences

ROS dye

Supplier: Enzo Life Sciences

Argatroban is a synthetic peptidomimetic thrombin inhibitor which is in clinical use. It presents significant advantages as an anticoagulant in deep vein thrombosis, stroke prevention in atrial fibrillation and thromboembolic disease and especially in patients with coronary artery disease and heparin-induced thrombocytopenia.

Supplier: TCI America

CAS Number: 22246-18-0
MDL Number: MFCD06410891
Molecular Formula: C9H9NO2
Molecular Weight: 163.18
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 236

Supplier: TCI America

CAS Number: 488-81-3
MDL Number: MFCD00064291
Molecular Formula: C5H12O5
Molecular Weight: 152.15
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Melting point (°C): 102

Supplier: TCI America

CAS Number: 604-69-3
MDL Number: MFCD00006597
Molecular Formula: C16H22O11
Molecular Weight: 390.34
Purity/Analysis Method: >99.0% (GC)
Form: Crystal
Melting point (°C): 132
Specific rotation [a]20/D: 4.5 deg (C=5, CHCl3)

Supplier: TCI America

CAS Number: 604-68-2
MDL Number: MFCD00064071
Molecular Formula: C16H22O11
Molecular Weight: 390.34
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Melting point (°C): 113
Flash Point (°C): 150
Specific rotation [a]20/D: 106 deg (C=1.5, MeOH)

Supplier: TCI America

6-Methoxy-1,2,3,4-tetrahydroisoquinoline, Purity: >96.0%(GC)(T), CAS Number: 42923-77-3, Molecular Formula: C10H13NO, Molecular Weight: 163.22, Synonyms: Longimammatine, Size: 1G

Supplier: TCI America

1,2,3,4-Tetrahydroquinoxaline, Purity: >98.0%(GC)(T), Cas number: 3476-89-9, Molecular Formula: C8H10N2, Molecular Weight: 134.18, Appearance: White - Deep yellow red solid crystal powder, Size: 5G