21010 Results for: "(11bS)-2,6-Bis[bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl]-3,5-dihydrospiro[4H-dinaphtho[2,1-c"

Supplier: Thermo Scientific

This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology. This gene belongs to a group of vacuolar protein sorting genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Supplier: PARALLAX INC.

8-core Propeller microcontroller pre-wired to a host of popular peripherals for fast and fun experiments.

Supplier: Mortech Manufacturing

The Qlicksmart® Blade Removal System is a medical safety device specially designed, engineered and manufactured to comply with recently revised OSHA Bloodborne Pathogens Standards. Qlicksmart® offers single-handed removal and immediate containment of contaminated scalpel blades which dramatically reduces the risk and cost of injury to the user.

Supplier: LONZA PHARMA - BIOSCIENCE CA

The SE Cell Line 4D-Nucleofector® X Kit L is one of our three 4D-Nucleofector® Kits that is suited for transfecting difficult-to-transfect cell lines in the 100 µl Nucleocuvette® Vessel format when working with the 4D-Nucleofector® X Unit.

Supplier: Biotium

P21 / WAF1, Monoclonal antibody, Clone: CIP1/823 + DCS-60.2, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF405S, Immunogen: Recombinant full-length human CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2), Application: IF, Size: 100uL

Supplier: Hamilton

Hamilton Company offers the most comprehensive selection of standard and custom syringes in the industry

Supplier: Vileda Professional - FHP

The easiest, most effective way to clean floors, walls, and ceilings within controlled environments.

Supplier: GRANT USA INC.

Built to the highest standard and specifications, and incorporating the latest technology, the SUB Aqua Pro advanced unstirred water bath range supports even the most demanding applications requiring accurate temperature control

Supplier: Biotium

CD63 Monoclonal antibody, Clone: NKI-C3, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Smooth plasma membrane fraction of MeWo cells, Application: IF, Immunohistology (formalin), Western, FC, Size: 500 uL

Supplier: Prosci

ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting.ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting (Samyn-Petit et al., 2000 [PubMed 10742600]).

Supplier: Prosci

TMX2 is a single-pass type I membrane protein and contains 1 thioredoxin domain. Thioredoxin plays an important role in various cellular processes through redox regulation. The molecular cloning and characterization of one member of the thioredoxin superfamily, designated as TMX2.The TMX2 cDNA consists of 1644 nucleotides and contains an open reading frame encoding a protein of 372 amino acids with a predicted molecular mass of 42.5 kDa and an isoelectric point of 8.94. The TMX2 protein may possess an N-terminal signal peptide, a potential transmembrane domain, an Myb DNA-binding domain repeat signature, a thioredoxin consensus pattern, an endoplasmic reticulum (ER) membrane retention signal (KKXX-like motif), and a dileucine motif in the tail.

Supplier: VWR International

Economical, disposable tools for transferring, collecting, and handling chemical and biological materials.

Supplier: NABERTHERM INC.

With their maximum working temperature of up to 300 °C and air circulation, the ovens achieve nearly perfect temperature uniformity.

Supplier: HITACHI HIGH-TECH AMERICA, INC.

The LA8080 amino acid analyzer by Hitachi combines the robustness and quality of Hitachi LC products with the performance of a post-column ninhydrin application. These instruments are used for a wide range of purposes - from measuring umami components of foodstuffs or the active ingredients in health supplements, to quality control for biopharmaceutical products. Based on components of Hitachi HPLC instruments the new bench top design enables gives scientists new possibilities in their analysis workflow. Moreover, the new design occupies 30% less surface area than its predecessors.

Supplier: Labconco

Chairs feature a durable, scratch-resistant seat mold, a welded frame with an elevated 25” chair height, and an ergonomically designed padded arm specifically contoured and angled at 10° to support the patient’s arm in a fully extended position for easier venipuncture

Supplier: DuPont

DuPont™ Tychem® 10000 FR NFPA 1991 (2016 edition) certified suits were one of the first limited-use garments to be certified to NFPA 1991 (2016 edition) in a single-skin construction.

Supplier: Thermo Fisher Scientific

Thermo Scientific™ TSX Series high-performance blood bank refrigerators offer a sustainable choice for whole blood and blood components refrigeration.

Supplier: Prosci

Exodus 2 is one of several CC cytokine genes clustered on the p arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterised by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils.

Supplier: Electron Microscopy Sciences

The EasyDip™ Slide Staining System has two components: a square staining jar and a 12-position vertical slide staining rack. Jars can be loosely joined to each other laterally using the stainless steel holder making sure they are kept in the same order when moved around on the lab counter. The jars are available in five different colors to help better identity contents or applications.

Supplier: Thermo Scientific

This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology. The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Supplier: Metropolitan Wire

Standard shelves up to 121.9 cm (48") in length can support up to 363 kg (800 lbs.) per level. Standard shelves longer than 121.9 cm (48") and all super wide shelves can support up to 272 kg (600 lbs.) per level.

Supplier: Prosci

TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.

Supplier: Prosci

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several death receptors including DR3, DR4, DR5, and DR6 have been identified. Like TNF-R1, DR6 (also known as TNFRSF21) interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-B and JNK. DR6 is widely expressed in human tissues and cell lines (2). Recently, DR6 was found to interact with an amino-terminal fragment of the Beta-amyloid protein (APP) in neurons, activating a caspase 6-dependent apoptotic event leading to axonal degeneration and pruning (3).

Supplier: ONSET COMPUTER CORPORATION

The InTemp CX402 VFCxxx is a bluetooth temperature data logger with a glycol bottle that monitors temperatures in refrigerators and freezers for clinics participating in the CDC vaccines for children program as well as hospitals, clinics, and WHO sites.

Supplier: Proteintech

DX21 protein belongs to DEAD box protein family which is characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). As a putative RNA helicase, DDX21 unwinds double-stranded RNA, folds single-stranded RNA and is involved in process including ribosomal RNA biogeneis, RNA editing and general transcription. Interaction of DDX21 and c-Jun was reported in ribosomal RNA processing. DDX21 exists as two isoforms, molecular weight of modified isoform one is about 87 -100 kDa, and the post-modified isoform is about 75-85 kDa. Catalog# 10528-1-AP is a rabbit polyclonal antibody raised against N-terminal of human DDX21.

Supplier: Prosci

TBX21 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.

Supplier: Saint Gobain Life Sciences

PharMed® BPT is designed to maintain fluid integrity during fluid transport. Transporting biocompatible fluids through a peristaltic pump limits the risk of fluid contact with any portion of the pump itself. PharMed® BPT tubing has been formulated to withstand the rigors of peristaltic pumping action while providing the biocompatible fluid surface required in sensitive applications.

Supplier: PHC Corporation

These ULT freezers are purpose-built for reliable, long-term sample storage and designed to achieve and maintain temperature uniformity and stability. The VIP ECO SMART series combine next generation engineering with SMART control technology to provide ULT freezers with excellent energy efficiency and enhanced security and operation. Proven frost mitigation technology lowers the total cost of ownership.

Supplier: Justrite

This Single Cylinder Hand Truck with Hoist Ring provides safety when moving and storing of gas cylinders.

Supplier: Cytiva

Cytiva's Whatman Grade 540 is a high-purity, acid-treated cellulose lab filter paper. Mechanically strong Grade 540 is well suited for quantitative or gravimetric analysis of strongly acidic or alkaline samples.