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Specifications
- Antibody type:Primary
- Antigen name:CD31 / PECAM-1
- Clonality:Monoclonal
- Clone:C31.3 C31.7 C31.10
- Gene ID:Unigene ID: 376675 , 514412
- Host:Mouse
- Isotype:IgGs
- Reactivity:Rabbit,Cynomolgus monkey,Human,Rat
- Antigen symbol:PECAM1
- Conjugation:CF® 647
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:100 μL
- Western blot:Yes
- Storage buffer:PBS/0.1% BSA/0.05% azide
- Concentration:0.1 mg/mL
- Supplier No.:BNC471099-100
Specifications
About this item
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Type: Primary
Antigen: PECAM1
Clonality: Monoclonal
Clone: Clone C31.3 C31.7 C31.10
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Cynomolgus monkey, Human, Rabbit, Rat