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Specifications
- Antibody type:Primary
- Antigen name:A-Raf Proto-Oncogene, Serine/Threonine Kinase
- Antigen symbol:ARAF
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 555
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Size:100 µL
- Environmentally Preferable:
- Cross adsorption:No
- Form:liquid
- Gene ID:369
- Antigen synonyms:RP1-230G1.1|ARAF1|RAFA1|PKS2|A-RAF
- Modification:phospho-Tyr301/Tyr302
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10368-788
- Supplier No.:BS-3421R-A555
Specifications
About this item
The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: ARAF
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Supplier: VWR International
Supplier: BDH
Supplier: VWR International
Supplier: Corning
Supplier: VWR International
Supplier: VWR International