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Specifications
- Antibody type:Primary
- Antigen name:Glyceraldehyde 3-Phosphate Dehydrogenase
- ChIP:Yes
- Clonality:Monoclonal
- Host:Mouse
- Isotype:IgG1
- Reactivity:Cat
- Antigen symbol:GAPDH
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Western blot:Yes
- Antigen synonyms:GAPDH|G3PD|CDABP0047|GAPD|Glyceraldehyde-3-phosphate dehydrogenase|Peptidyl-cysteine S-nitrosylase GAPDH|HEL-S-162eP|OK/SW-cl.12
- Storage buffer:Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide
- Storage temperature:Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. We recommend to parafilm vials during storage to prevent evaporation of buffer.
- Immunogen:Rabbit muscle GAPDH.
- Tested applications:Affinity Purification, Control, Purification
- Purification:Protein A purified
- Cat. no.:89352-354
- Supplier No.:GTX28245
Specifications
About this item
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age-related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is constitutively expressed in almost all tissues at high levels, therefore becoming the marker of choice when a loading control in Western blotting is required. Some physiological factors, such as hypoxia and diabetes, increase GAPDH expression in certain cell types.
Type: Primary
Antigen: GAPDH
Clonality: Monoclonal
Clone:
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Cat