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Specifications
- Antibody type:Primary
- Antigen name:Rac GTPase activating Protein 1
- Clonality:Polyclonal
- Gene ID:29127
- Host:Goat
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:RACGAP1
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:50 μg
- Western blot:Yes
- Antigen synonyms:GTPase activating protein|RAC GTPase-activating protein|RACGAP1|RAC GTPase- activating protein 1|GTPase activating protein ID-GAP
- Storage buffer:Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
- Storage temperature:Upon receipt - Keep as concentrated solution. Aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:0.5 mg/ml
- Immunogen:Peptide with sequence GRQGNFFASPMLK, from C Terminus of the protein sequence according to NP_037409
- Tested applications:WB
- Purification:IgG fraction
- Cat. no.:89361-204
- Supplier No.:GTX22270
Specifications
About this item
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM]
Western Blot - Approx 60kDa band seen in Human Testis lysate. Recommended for use at 0.2-1.0?g/ml. Please note that we observe a 60kDa band as suggested in the literature (for example, see Toure et al., [J Biol Chem 1998 Mar 13;273(11):6019-23]), which is different to the predicted MW of approx. 70kDa.
Type: Primary
Antigen: RACGAP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Goat
Isotype: IgG
Reactivity: Human