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Specifications
- Antibody type:Primary
- Antigen name:Kirsten Rat Sarcoma Viral Oncogene Homolog
- Clonality:Monoclonal
- Clone:F132-62
- Gene ID:3845
- Host:Mouse
- Isotype:IgG2b
- Reactivity:Human
- Antigen symbol:P21 RAS
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:50 μg
- Antigen synonyms:KI-RAS|KRAS2|KRAS1|K-RAS2B|NS3|K-RAS4B|NS|RASK2|C-K-RAS|K-RAS4A|K-RAS2A|RALD|CFC2
- Storage buffer:0.05 M sodium phosphate buffer, 0.2% gelatin with =0.1% sodium azide
- Storage temperature:Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
- Concentration:0.1 mg/ml
- Immunogen:Recombinant full length protein (Human).
- Tested applications:ICC/IF, IHC-P, IHC-Fr, IP
- Purification:Protein A purified
- Cat. no.:89351-288
- Supplier No.:GTX16907
Specifications
About this item
The human ras gene family consists of three identified members which encode proteins of 21 kDa. Human c-H-ras and c-K-ras are the cellular homologs of v-Hand v-K-ras originally isolated from Harvey and Kirsten strains of rat sarcoma viruses. The third family member is designated c-N-ras. Normal cellular ras genes are referred to as protooncogenes and have the potential for activation to oncogenes by mutations occurring in codons 12, 13 and 61. Such mutated, activated and transforming ras genes have been identified and isolated from human tumors and cultured tumor cells. Although the expression patterns of ras proto-oncogene proteins in normal human tissues are known, similar information for activated ras oncogene encoded p21s and their relevance to human disease diagnosis and prognosis remains to be determined.
For IF: Use at a concentration of 1.5 - 2.5 ?g/ml. For IHC-P: Use at a concentration of 4 - 6?g/ml. For IHC-Fr: Use at a concentration of 4 - 6?g/ml. For IP: Use at a concentration of 3 - 5?g/ml. Not suitable for use in Western Blot. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Type: Primary
Antigen: P21 RAS
Clonality: Monoclonal
Clone: F132-62
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Human