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Specifications
- Antibody type:Primary
- Antigen name:Rac Gtpase Activating Protein 1
- Clonality:Monoclonal
- Clone:23A8
- Gene ID:29127
- Host:Mouse
- Isotype:IgG2b
- Reactivity:Human
- Antigen symbol:RAC
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Size:50 μg
- Western blot:Yes
- Antigen synonyms:MgcRacGAP|HsCYK-4|ID-GAP|CYK4
- Storage buffer:Preservative: 0.05% Sodium Azide; Constituents: 0.15M Sodium Chloride, 0.1M Tris-glycine. pH 7.4
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:1 mg/ml
- Immunogen:Recombinant full length protein (Human).
- Tested applications:IHC-Fr, IP, WB
- Purification:Protein G purified
- Cat. no.:89359-564
- Supplier No.:GTX13048
Specifications
About this item
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
IHC-Fr: Use at a concentration of 10 ?g/ml. This concentration is recommended to detect RAC in rat brain fixed with 4% paraformaldehyde, 2% acetic acid. IP: Use 4 ?g to precipitate RAC from a rat brain microsomal protein preparation. WB: Use at a concentration of 0.5 - 2 ?g/ml. Detects a band of approximately 21 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: RAC
Clonality: Monoclonal
Clone: 23A8
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Human