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Specifications
- Antibody type:Primary
- Antigen name:Glucosidase, Beta, Acid 3 (Gene/Pseudogene)
- Clonality:Polyclonal
- Gene ID:57733
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:GBA3
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:100 μl
- Western blot:Yes
- Antigen synonyms:CBGL1|KLRP|GLUC|CBG
- Storage buffer:0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
- Molecular weight:18 kDa
- Storage temperature:Keep as concentrated solution. Aliquot and store at –20 °C or below. Avoid multiple freeze-thaw cycles.
- Concentration:0.55 mg/ml
- Immunogen:Recombinant protein encompassing a sequence within the center region of human GBA3. The exact sequence is proprietary.
- Tested applications:IHC-P
- Purification:Purified by antigen-affinity chromatography.
- Cat. no.:89358-686
- Supplier No.:GTX116696
Specifications
About this item
GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM]
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Type: Primary
Antigen: GBA3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human