Hamilton Company offers one of the most comprehensive selections of chromatography columns in the industry.

• LC/MS Applications, Synthesized DNA, and Small Molecules
• pH Stable from 1 - 13
• Excellent Durability (Stable to any Concentration of Water or Organic Solvent)
• Half the Operating Pressure of other Polymer Columns
• Unique Bonding of C18 to a Polymer Support
• Custom Hardware Dimensions Available
• Buffer strength 0.0 - 0.5N

Each column is manufactured under rigorous criteria and tested for resolution and retention time accuracy.

Hamilton PRP-h1 reversed phase columns are ideal for applications that require a high degree of column-to-column and batch to batch consistency (e.g., quality assurance, clinical trials). Because of the unique polymer bonding of the C18 to the PS-DVB support, PRP-h1 columns maintain their performance characteristics longer than many C8 or C18 columns. While many column manufacturers rely on other sources for their raw silica support, Hamilton manufactures its PRP-h1 support, thus assuring a consistent supply of PRP-h1 columns.

PRP-h1 columns are packed with a poly(styrene-divinylbenzene) material. This support is pressure stable up to 5000 psi, and highly cross-linked to prevent shrinkage or swelling (common in other polymeric columns). Since the support is polymeric, column lifetime is longer for PRP-h1 than C4, C8, or C18 columns. Regardless of whether you use ion-pair reagents or high percentage aqueous buffers (80 to 100%) for your separation, PRP-h1 columns outlast silica-based columns under most conditions. PRP-h1 columns will last approximately one year, while C8 and C18 columns will last only 3 to 4 months.

Hamilton PRP-h1, 100 Å C18 bonded to a polymeric support for oligonucleotides, NSAIDs and many other HPLC applications.

Guard columns are modular and cartridge replacement is easy and tool-free. Guard column cartridge holders are available in stainless steel and PEEK materials, depending on the column. Both designs are optimized to reduce dead volume and prevent extra column band broadening.

Holders for the cartridges are reusable indefinitely. As with all guard columns these should be installed before the analytical column and after the injection valve.

Housing Material: Anodized Aluminum
Connecting Tubing Size/Material: ¹/₁₆" Out.Ø., 0.28 mm Int.Ø/316 Stainless Steel
Cartridge Materials,
Barrel: CTFE
Frits: 316 Stainless Steel
Sleeve: 304 Stainless Steel
Frit Porosity: 2 µm
Cartridge Dimension: 20×2.3 mm Int.Ø.
Cartridge Bed Volume: 80 µl
Chemical Compatibility: Recommended for use with virtually all solvents except high concentrations of sodium chloride.