Tris(hydroxymethyl)aminomethane (TRIS, Trometamol), EMPROVE® ESSENTIAL Ph. Eur., BP, JPC, USP, SAFC®
Supplier: MilliporeSigma
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About this item
Synonyms: Tromethamine,Tris(hydroxymethyl)methylamine,2-Amino-2-(hydroxymethyl)propane-1,3-diol,2-Amino-2-(hydroxymethyl)-1,3-propanediol,Trizma(R) base,TRIS base
Formula:NH₂C(CH₂OH)₃
MW:121.14 g/mol
Boiling Pt:357 °C (1013 hPa)
Melting Pt:169…172 °C
Density:1.328 g/cm³ (20 °C)
MDL Number:MFCD00004679
CAS Number:77-86-1
Merck Index:12,09902
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:Boiling Pt:
:Boiling Pt: 357 °C (1013 hPa)
:Melting Pt:
:Melting Pt: 169 to 172 °C|Melting Pt: 169…172 °C
:Flash Pt:
:Flash Pt:
:M.W. 121.14 g/mol
:Tris(hydroxymethyl)aminomethane (TRIS, Trometamol)
Storage Temperature:Ambient
EINECS:201-064-4
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Specification Test Results
- Assay (acidimetric; calculated on dried substance):99.0-100.5%
- Appearance of solution (5%, water):Passes test
- Arsenic (As):0.00002% max
- Chloride (Cl):0.001% max
- Colony count, aerobic bacteria:100CFU/g max
- Colony count, yeast and mold:100CFU/g max
- Endotoxins:0.03I.U./mg max
- Escherichia coli:Absent in 10 g
- Filtration test (0.45 µm):Conforms
- Heavy metals (as Pb):0.0010% max
- Identification A:Passes test
- Identification B:Passes test
- Identification C:Passes test
- Iron (Fe):0.0010% max
- Loss on drying (105°C):0.5% max
- Melting point:168-172°C
- Organic volatile impurities (USP/NF):Conforms
- Other Residual Solvents (Ph.Eur./ICH):Excluded by production process
- pH (5%, water):10.0-11.5
- pH of a 1% aqueous solution:10.3-10.7
- Pseudomonas Aeruginosa:Absent in 10 g
- Related substances (TLC):Conforms
- Residual solvents (Ph.Eur./ICH) class 3:0.5% max
- Salmonella:Absent in 10 g
- Staphylococcus Aureus:Absent in 10 g
- Sulfate (SO4):0.005% max
- Sulfated ash:0.1% max
Specification Test Results
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