To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Description:QuantiFluo™ Urokinase inhibitor screening assay kit
- Size:100 tests
- Cat. no.:77441-672
Specifications
About this item
For evaluation of drugs and screening potential inhibitors of urokinase.
- Safe
- Non-radioactive assay
- Fast
- Assay is completed within a 30 minutes reaction time
- Homogeneous 'mix-incubate-measure' type assay
- Can be readily automated to assay thousands of samples per day
UROKINASE PLASMINOGEN ACTIVATOR (urokinase, uPA) is a key serine protease involved in the degradation of the extracellular matrix that catalyzes the conversion of plasminogen to active plasmin. It acts as a thrombolytic agent to break up blood clots and when over-expressed, has been reported to influence the growth of certain malignant tumors (breast, prostate, etc.). BioAssay Systems’ DUKI-100 Kit provides a convenient fluorimetric means to screen for potential urokinase inhibitors. In this assay, the fluorimetric substrate reacts with urokinase and an inhibitor will decrease the fluorescence at λex/em = 380/450 nm.