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Specifications
- Antibody type:Primary
- Antigen name:HDAC5 Ser498
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG (H, L)
- Reactivity:Human,Bovine,Rat,Mouse
- Conjugation:Unconjugated
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:100 µl
- Western blot:Yes
- Storage buffer:0.01 M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol
- Storage temperature:Store at –20 °C for 12 months.
- Concentration:1 µg/µl
- Purification:Purified by Protein A
- Packaging:Vial
Specifications
About this item
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Type: Primary
Antigen: HDAC5 Ser498
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG (H, L)
Reactivity: Human, Mouse, Rat, Bovine