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Specifications
- Antigen name:Pertuzumab
- Clonality:Monoclonal
- Clone:11H4
- Host:Mouse
- Isotype:IgG1 kappa
- Conjugation:Unconjugated
- ELISA:Yes
- Size:40 μg
- Cross adsorption:No
- Form:Lyophilized
- Storage buffer:This product is lyophilized with PBS, pH 7.2, containing 0.02% sodium azide
- Storage temperature:The lyophilized product remains stable up to 1 year at −20 °C from date of receipt. Upon reconstitution, it can be stored for 2 - 3 weeks at 2 - 8 °C or for up to 12 months at −20 °C or below. Avoid repeated freezing and thawing cycles
- Concentration:Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml
- Immunogen:Pertuzumab
- Cat. no.:77007-500
- Packaging:Vial
Specifications
About this item
Pertuzumab (also called 2C4, trade name Perjeta) is a monoclonal antibody used in combination with trastuzumab and docetaxel for the treatment of metastatic HER2-positive breast cancer; it also used in the same combination as a neoadjuvant in early HER2-positive breast cancer. The epitope for pertuzumab is the domain of HER2 where it binds to HER3, and pertuzumab prevents the HER2/HER3 dimer from forming, which blocks signalling by the dimer to prevent HER2 from functioning. Anti-Pertuzumab antibody (11H4), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Pertuzumab.
- High specificity
- High affinity
- High stability
GenScript has developed a broad range of off-the-shelf anti-idiotype antibodies against blockbuster drugs to help accelerate your research of biosimilars.
Type:
Antigen: Pertuzumab
Clonality: Monoclonal
Clone: 11H4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: