About this item
Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. It binds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. It induces interleukin 6 (IL-6) and tumor necrosis factor alpha (TNFα) expression in monocytes, and promotes type 2 T helper (Th2) cell-mediated immune responses. Its production is upregulated in resting monocytes following granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS) stimulation.
- Animal-free
- US-made recombinant proteins
- Strict quality standards
- Low manufacturer pricing
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