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Specifications
- Antibody type:Primary
- Antigen name:Beta-casein
- Clonality:Polyclonal
- Gene ID:CSN2
- Host:Rabbit
- Isotype:IgG
- Reactivity:Bovine
- Antigen symbol:CASB
- Conjugation:Unconjugated
- ELISA:Yes
- Size:100 µg
- Western blot:Yes
- Form:Lyophilized
- Shipping temperature:Room (ambient) temperature
- Immunogen:Bovine beta-casein peptides
- Purification:Affinity purified
- Cat. no.:76334-034
Specifications
About this item
Beta-casein has an important role in determination of the surface properties of the casein micelles. it is cleaved into 3 chains (casoparan, casohypotensin and antioxidant peptide). Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide. Casohypotensin acts as a bradykinin-potentiating peptide and induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A. Antioxidant peptide has antioxidant activity (ref: uniprot.org.).
Bovine milk contains two types of beta-casein protein, A2 or A1. Recent studies have shown that milk containing the A1 beta casein protein can contribute to issues including gastrointestinal discomfort after ingestion. There is some evidence of a link between ingestion of A1 beta casein protein and the development of Type 1 diabetes.
Applications: ELISA and western blotting (1:5,000 - 1: 20,000). Do not use skim milk for blocking and dilution of assay reagents, BSA is recommended (3-5% in blocking and 1-3% in dilution buffer). Biosensis recommends that optimal working dilutions should be determined by the end user.
Type: Primary
Antigen: CASB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Bovine