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Specifications
- Animal-free:Y
- Gene ID:10673
- Protein Function:Cytokines and Growth Factors
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Conjugation:Unconjugated
- Size:50 µg
- Biological activity:Determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0 ug/ml.
- Protein synonyms:THANK|ZNTF4|TALL-1|TNFSF20|BLyS|TNFSF13B|B cell Activating Factor belonging to the TNF family
- Protein/peptide name:BAFF
- Purity:95%
- Molecular weight:17 kDa
- Sequence:AVQGPEETVT QDCLQLIADS ETPTIQKGSY TFVPWLLSFK RGSALEEKEN KILVKETGYF FIYGQVLYTD KTYAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PRENAQISLD GDVTFFGALK LL
- Endotoxin level:low
- Formulation:Lyophilized
- Shipping temperature:Ambient
- Cat. no.:76303-908
Specifications
About this item
BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors, TACI, BCMA and BAFFR. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant Human soluble BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.