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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:4B3.B5.F3.B7
- Host:Mouse
- Isotype:IgG1 kappa
- Antigen symbol:HbG
- ELISA:Yes
- Size:25 µL
- Western blot:Yes
- Shipping temperature:Dry Ice
- Purification:Protein A purified
- Cat. no.:76234-988
Specifications
About this item
HbF antibodies detect the hemoglobin gamma isoform subunit. Functional alternate hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 gamma subunits (alpha-2 gamma-2). Hemoglobin F is elevated in newborns, reaching adult levels by 12 months. HbF levels are increased to as much as 5% to 10% in normal pregnancy. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Hemoglobin variants arise from mutations in the globin genes and sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. HbF antibody does not react other forms of Hb. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.
Anti-Hemoglobin beta F (MOUSE) antibody is suitable for use in Western Blotting. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 16 kDa.
Type: Primary
Antigen: HbG
Clonality: Monoclonal
Clone: 4B3.B5.F3.B7
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: