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Specifications
- Gene ID:Q8K3I6
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Mouse
- Size:10 µg
- Storage conditions:Store vial at 4 °C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL) . For best results aliquot contents and freeze at –20 °C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
- Endotoxin content:Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein.
- Biological activity:Mouse p28 biological activity was measured via dose-dependent inhibition of TGFß and IL-6-induced IL-17A expression in mouse CD4 splenocytes. 50ng/ml of Mouse p28 is capable of inhibiting >25% of IL-17A expression in this assay. no acceptance criteria limits established.
- Reconstitution instructions:10µl (10-100µl)
- Protein synonyms:IL-27 subunit alpha|Interleukin-27 subunit alpha|IL-27-A cytokine|IL27-A|p28|IL-30
- Protein/peptide name:Il27
- Purity:>97%
- Formulation:Lyophilized
- Shipping temperature:Ambient
- Supplier No.:010-001-B54
Specifications
About this item
Mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions. Recombinant mouse p28 is a single-chain 207 amino acid peptide with a mass of approximately 23,697 Daltons.