About this item
This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Type: Primary
Antigen: EGFR
Clonality: Monoclonal
Clone: Clone GFR1195 31G7
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human
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Specifications
- Catalog No:
- 75925-616
- 75924-546
- Antigen name:
- EGFR
- EGFR
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Clone:
- GFR1195 31G7
- GFR1195 31G7
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 488293
- Unigene ID: 488293
- Isotype:
- IgG2a kappa
- IgG2a kappa